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10 Cards in this Set
- Front
- Back
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Thiazide electrolytes excreted
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Na/Cl/Mg excretion
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Thiazide kidney
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more filtered than secreted. in tubule luman (renal insufficiency)
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Thiazide dosing
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12.5-50mg/day. slow in geriatrics
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Thiazide main drug
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hydrochlorothiazide (Diuril)
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Thiazide S/E
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renal insufficiency*, hypokalemia, hyperglycemia* if borderline may make DM
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Chlorthalidone (Hygroton)
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longer acting diuresis (24-72hr)
first line drug cheap |
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ALLHAT
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no difference in primary ep of chd mortality or nonfatal mi
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ACE-I Mech of action
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decreases vasoconstriction
decreases aldostron production and consequently na/h2o retention increases vasodilatory prostaglandin |
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ACE-I drugs
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Captopril
Enalapril fosinopril lisinopril ramipril |
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ACE-I dosing
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start slow and increase q 1-4wks til goal
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