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List 4 Carbapenems.

Imipenem


Meropenem


Ertapenem


Doripenem

أربعة أصدقاء : ايمي ، ميرو، ارتا، دوري

What is the route of administration of Carbapenems?

Parenteral

which drug you should always administer with Imipenem? & why?

Cilastatin (inhibitor of renal dehydropeptidase I).


To decrease inactivation in renal tubules.

Carbapenems are used to fight what types of bacteria?

Gram + cocci, Gram - rods, & anaerobes.

What side effects are associated with carbapenems?

GI distress, Skin rash, CNS toxicity (Seizures) at high plasma levels.

Carbapenems belong to which class?

Beta- lactams