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108 Cards in this Set
- Front
- Back
Similar cells with common function come together to form |
Tissues |
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Histology |
Study of tissues |
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Tissues classified into 4 catagories |
1. Epithelial 2. connective 3. muscle 4. nervous |
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Extracellular matrix (ECM) |
produced by cells, water, protein fibers, dissolved molecules found in all tissues but at varying degrees. |
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Epithelial tissues |
1. covers body surfaces 2. lines the body cavities 3. forms most of the glands
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Characteristics of epithelial tissues |
cellularity, polarity, basement membrane, avascularity, extensive innervation, and high regeneration capacity |
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Cellularity Characteristics of Epithelial tissue |
epithelial tissue composed of tightly packed cells, minimal amount of ECM
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polarity Characteristics of Epithelial tissue |
epithelial tissues exhibits polarity, cells have an apical surface (exposed surface to open space) and a basal surface (surface attached to underlying connective tissue) additionally the lateral surface of cells are attached via junctions |
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Basement membrane Characteristics of Epithelial tissue |
epithelium is bound to basement membrane at its basal surface, consists of 3 layers: lamina lucida, lamina densa, reticular lamina, forms a selective barrier between epithelial tissue and underlying connective tissue |
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Avascularity Characteristics of Epithelial tissue |
epithelial tissue lack blood vessals, nutrients to epithelial tissue are provided directly via apical surface or by diffusion across the basal surface from the connective tissue |
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Extensive innervation Characteristics of Epithelial tissue |
richly innervated, must have the ability to detect environmental changes |
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High regeneration capacity Characteristics of Epithelial tissue |
ability to regenerate achieved by the stem cells of epithelial tissue located adjancent to the basement membrane |
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Function of epithelial tissue |
Physical protection, selective permeability, secretions, sensations |
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Physical protection Functions of Epithelial Tissue |
protection of external and internal surfaces of dehydration, abrasion, and destruction by physical, chemical or biological agents |
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Selective permeability Functions of Epithelial Tissue |
any substance that enters or leaves the body must pass through epithelium serve as "gatekeepers", epithelium permeable to some substances and could be impermeable to others |
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Secretions Functions of Epithelial Tissue |
specialized epithelial cells have the ability to produce secretions and therefore can function as a unicellular gland or multicellular gland |
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Sensation Functions of Epithelial Tissue |
epithelium is highly innervated and has the ability to detect changes and convey this information via nervous system (touch, pressure, temp, and pain) |
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Can epithelial tissue be classified by number of cells layers or cell shapes |
yes |
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Simple epithelium Cell layers |
one cell layer thick all cells are attached to basement membrane, found in areas where there is minimal stress and where filtration, absorption or secretion is primary function (lining of air sacs of lung, intestines, blood vessels |
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Stratified epithelium Cell layers
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two or more layers of epithelial cells, only deep layer in direct contact with basement membrane, found in areas exposed to abrasion, mechanical stress, cells in basal layer continuously regenerate as apical surface cells are damaged (skin, internal lining of pharynx, esophagus) |
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Pseudostratified epithelium Cell layers
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looks stratified because cells nuclei are distributed at different levels, all cells are attached to basement membrane therefore can be classified into simple epithelium |
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Squamous cell shape |
flat, wide, irregular shape, nucleus flattened |
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Cuboidal Cell shape |
Cube-like round edges, nucleus spherical and located in center of cell
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Columnar cell shape |
slender and taller than wider, oval nucleus and located in basal side of cell |
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Transitional cell shape |
have the ability to change shape depending on how stretched the epithelium is if relaxed will have polyhedrant appearance and distended flattened cells
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Simple squamous |
single layer of flattened cells , extremely delicate and highly specialized to allow rapid movement of molecules via diffusion, osmosis, filtration, found in air sacs of lungs, lining of lymph and blood vessels (endothelium), serous membrane of body cavities (mesothelium) |
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Simple cuboidal |
single layer of cells about as tall as they are wide, absorb fluids and other materials across its apical surface to secret substances, found in kidney tubules, ducts and secretory regions of glands, surface of ovary, thyroid gland follicles |
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Simple columnar |
single layer of cells taller than wide, ideal for secretory and absorptive functions |
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Nonciliated simple columnar |
absorption and secretion, often contains microvilli and unicellular glands termed goblet cells (secrete mucin) (digestive tract stomach to anal canal) |
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Ciliated simple columnar |
secretion of mucin and movement of mucus, goblet cells present, oocyte movement through uterine tube, found in larger bronchioles of respiratory tract and lining of uterine tubes |
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Pseudostratified columnar |
appears as multiple layers but not truly stratified because all cells are in direct contact to basement membrane, |
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Pseudostratified ciliated columnar |
have cilia on apical surface and can be found in larger air passageways of respiratory system, larynx, pharynx, trachea and bronchi |
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Psedostratified nonciliated columnar |
no cilia and can be found in male urethra and epididymis |
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Stratified squamous |
multiple cell layers only the deepest layer in contact with basement membrane, protection of underlying tissue |
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Nonkeratinized stratified squamous |
superficial cells are alive and kept moist, lining of oral cavity, part of pharynx, esophagus lining of vagina, and anus |
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. Keratinzed stratified squamous |
apical cells are dead and filled with keratin, epidermis of skin |
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Stratified cuboidal |
rare, two or more cell layers, cells of apical surface are columnar, protects and secretes, salivary glands, membranous part of male urethra |
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Stratified columnar |
rare, two or more cell layers, cells of apical surface are columnar, protects and secretes, salivary glands, membranous part of male urethra |
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Transitional |
different appearances depending on whether it is in a relaxed or distended state, important for distension and relaxation to accommodate urine volume, found in urinary bladder, ureters, and part of urethra |
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Glands |
unicellular or multicellular organs composed of epithelial tissue important for secreting substances for use elsewhere or for elimination, secretions include mucin, electrolytes, hormones, enzymes, urea |
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Exocrine glands |
originate form an invagination of epithelium that burrows into deeper connective tissue, connection with epithelium via duct a hollow tube into which gland secretes ( mammary glands, sweat glands, salivary glands |
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Unicellular glands |
one cell and can be found in simple columnar and pseudostratified ciliated columnar goblet cells |
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Multicellular glands |
numerous cells that work together to produce secretion |
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Simple glands |
single unbranched duct |
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Compound glands |
branched ducts |
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Merocrine |
pack secretions into vesicles and secrete via exocytosis (lacrimal, salivary, sweat, pancreas and gastric glands |
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Apocrine |
pinching off of apical portion of secretory cells and that becomes secretion (mammary glands, sweat glands (in axillary and pubic regions)) |
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Holocrine |
cells accumulate the product then the entire cells disintegrates and becomes secretion viscous mixture of cells products and product (sebaceous (oil) glands) |
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Connective Tissue |
Most diverse, abundant, and widely distrib |
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Functions of connective tissue |
o Support o Protection o Bind organs storage transport immune protection |
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Resident cells |
stationary cells permanently housed help support maintain and repair |
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Fibroblasts |
most abundant, produce fibers and ground substance components of ECM |
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Adipocytes |
fat cells collection of adipocytes= adipose tisse |
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Mesenchymal cells |
embryonic stem cell upon damage these cells will divide and give rise to a mesenchymal cell and the differentiated damaged cell |
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Fixed macrophages |
derived from monocytes, dispersed throughout and engulf damaged cells or pathogens upon encountering foreign material they secret chemicals that trigger the immune system |
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Wandering cells |
components of immune system and are continuously moving throughout connective tissue (leukocytes) |
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Mast cells |
small, mobile cells close to blood vessels, secret heparin (stop blood clotting) and histamine (dilate blood vessels) |
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Plasma cells |
B lymphocytes, produce antibodies (proteins that immobilize a foreign material) |
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Free macrophages |
mobile phagocytic that wander through the connective tissue (like fixed macrophages but are mobile) |
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Other leukocytes |
migrate through the blood vessel to connective tissue (neutrophils, lymphocyte |
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Protein fibers |
strengthen and support the tissue o Viscous- thick in blood o Semisolid- cartilage o Solid- bone |
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Collagen fibers |
unbranched, long fibers, strong, flexible, resistant to stretching, form 25% of body's protein appear white (white fibers) abundant in tendons and ligaments |
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Reticular fbers |
thinner than collagen, same proteins as in collagen except that are coated with glycoproteins, branched, tough but flexible found in stroma of organs such as lymph nodes, spleen, and liver |
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Elastic fibers |
made of protein of elastin, fibers branch and rejoin, important for stretch and recoil found in skin, lungs, arteries |
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Ground substance |
nonliving material produced by the connective tissue cells, connective tissue cells and fibers reside in ground substance made of glycosaminoglycans, water, preoteoglycan, adherent glycoproteins, ground substance and fibers collectively make the ECM |
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Physical protection
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bones of skull and thoracic cage protect vital organs |
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Support and structural framework
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bones serve as framework for our body, cartilage keeps air tubes like trachea open |
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Binding of structures
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ligaments bind bone to bone, tendons bind muscle to bone, dense connective tissue anchors skim to muscle and bone |
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Storage
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adipose connective tissue- major energy reserve, bone- reserve for calcium and phosphorus |
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Transport
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blood carries nutrients, gases, and wastes |
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Immune protection
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leukocytes are abundant within connective tissue they protect the body against disease |
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Embryonic connective tissue |
2 type mesenchyme mucous connective tissue |
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mesenchyme |
origin of all connective types found throughout the body of embryo and fetus |
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mucous connective tissue |
support of structures in umbilical cord found in umbilical cord of fetus |
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Loose Connective Tissue |
fewer fibers, more ground substance |
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Loose Connective Tissue Areolar |
abundant, viscous ground substance, scattered fibroblasts, many blood vessels, protects tissues and organs, binds some epithelial to deep tissue, found in papillary layer of dermis, subcutaneous layer (deep skin), surrounds organs, nerves, and blood vessels |
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Loose Connective Tissue Adipose |
closely packed adipocytes, nucleus pushed to edge of cell by large fat droplet, stores energy insulates, cushions, and protects found in subcutaneous layer and surrounds and covers most organs |
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Loose Connective Tissue Reticular |
viscous ground substance, scattered arrangement of reticular fibers, fibroblasts and leukocytes, provides stroma to lymphatic organs therefore it is found in spleen, lymph nodes, thymus, and bone marrow |
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Dense Connective Tissue |
more fibers, less ground substance |
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Dense Connective Tissue Regular |
densely packed, parallel arrays of collagen fibers, fibroblasts squeezed between layers of fibers, scarce ground substance, greatly reduced blood supply, attaches bone to bone (ligament), muscle to bone (tendon), resists stress applied in one direction |
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Dense Connective Tissue Irregular |
collagen fibers randomly arranged and clumped together, fibroblasts in spaces among fibers, more ground substance than in dense regular, extensive blood supply can withstand stresses applied in all directions found in most of dermis of skin, periosteum covering bone, covers cartilage |
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Dense Connective Tissue Elastic |
predominantly composed of elastic fibers and fibroblasts occupy some spaces between fibers, allows for stretching and recoil, found in walls of elastic arteries (aorta), trachea, vocal cords |
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Supporting Connective Tissue Cartilage |
semisolid matrix |
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Supporting Connective Tissue Hyaline |
glassy appearing matrix, sparsely arranged chondrocytes in lacunae, forms most of fetal skeleton provides support found in tip of nose, trachea, larynx, costal cartilage, articular ends of bones |
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Supporting Connective Tissue Fibrocartilage |
readily visible, numerous parallel collagen fibers, large chondrocytes in lacunae, resists compression and acts as a shock absorber in some joints, found in intervertebral discs, pubic symphysis, and menisci of knee joints |
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Supporting Connective Tissue Elastic |
abundant elastic fibers that form weblike mesh, chondrocytes in lacunae, functions to maintain shape while permitting extensive flexibility found in external ear and epiglottis of larynx |
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Bone |
solid matrix (osseous |
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compact bone |
calcified ECM containing osteocytes trapped in lacunae, arranged in osteons, provides levers for body movement, support soft structures, protects organs, stores calcium and phosphorus, found in bones |
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Spongy bone |
different organization from compact bone, contains hemopoetic tissue and is the site of hemopoeisis found in bones |
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fluid connective tissue Blood |
composed of formed elements (erythrocytes, leukocytes, platelets) and plasma, important for transport of gases, nutrients, wastes, hormones, immune defense, found in blood vessels and heart |
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fluid connective tissue lymph |
derived from blood plasma and is |
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Muscle tissue |
Composed of specialized cells that contract when stimulated by nervous system and produces movement |
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skeletal muscle |
long cylindrical, striated fibers (cells) arranged in parallel and unbranched fibers are multinucleated under voluntary contraction, function in moving the skeleton, attaches to bones and sometimes to skin |
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Cardiac muscle |
short striated cells typically branching uninucleated or binucleated intercalated discs between cells under involuntary control, pumps blood through heart found in heart wall (myocardium) |
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Smooth muscle |
nonstriated cells that are short, uninucleated, move and propelling of material through the internal organs found in walls of hollow organs such as intestines, stomach, airways, stomach, urinary bladder, uterus and blood vessels |
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Nervous tissue |
located within brain, spinal cord, and nerves, composed of neurons that receive, transmit, and process nerve impulses, also contains glial cells (supporting cells) |
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Neurons |
contain cell body, cell processes, dendrites and axons |
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Tissues form organs which are composed of two or more tissue types that work together to perform specific, complex functions examples |
stomach-epithelium, areolar, dense, smooth muscle and nervous tissues |
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Body membranes |
composed of epithelial layer bound to connective tissue, designed to line body cavities |
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All tissue develops from the 3 primary germ layers |
endoderm, mesoderm, ectoderm |
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Endoderm |
epithelial linging of respiratory tract, GI tract liver gall bladder, pancreas, thyroid and parathyroid glands |
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Medoderm |
muscle, dermis of skin, epithelial lining of blood vessels, connective tissues, heart |
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ectoderm |
epidermis of skin, nervous tissues, pituitary gland, adrenal medulla |
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Metaplasia |
epithelium changing into mature epithelium |
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hypertrophy |
an increase in size of existing cells |
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hyperplasia |
an increase in number of cells in a tissue |
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necrosis |
tissue death |
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hee; |
hello |