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20 Cards in this Set
- Front
- Back
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What is the embryologic origin of the thyroid gland?
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downgrowth of first and second pharyngeal pouches
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From which pharyngeal pouches are the inferior parathyroid glands derived
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third
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what is the arterial blood supply to the thyroid
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superior thyroid brance of external carotid
inferior thyroid branch of thyrocervical trunk |
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Venous drainage of the thyroid
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superior and middle thyroid V->anterior facial, IJ
inferior thyroid V->innominate V |
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What is the predominant glycoprotein found in colloid
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thyroglobulin
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Function of pendrin
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mediates exchange of iodide from thyrocyte to the colloid
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What is the NIS
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Na/I symporter that serves to concentrate I- into cells
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What are the three plasma proteins that bind thyroid hormones
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albumin
transthyretin thyroxine binding globulin |
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What is the fxn of parathyroid hormone
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-stimulates osteolysis and release of calcium and phosphorus from the bone.
-increase reabsorption of calcium and magnesium |
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What percent of the population has >4 parathyroid
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10%
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what percent of the population has <4 parathyroid
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3%
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what percent of parathyoid glands are located in the mediastinum
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2%
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T/F: The inferior glands vary more in location than the superior glands
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True
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Where are the inferior parathyroids typically located
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inferior and anterior to the inferior thyroid artery
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Where are the superior parathyroids typically located
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superior and posterior to the inferior thyroid artery
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what is the primary blood supply of the parathyroids
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superior and inferior parathyroid arteries (branches of inferior thyroid a)
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What are the 3 cell types comprising the parathyroid gland
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chief cells
clear cells oxyphil cells |
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Which cells produce PTH
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chief cells
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what percent of the parathyroid is composed of fat
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20-30%
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which terminal of PTH is active
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N-terminal
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