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109 Cards in this Set
- Front
- Back
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This direct cholinergic agonist is good for postoperative and neurogenic ileus AND urinary retention
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Bethanechol
"Bethan Call me if you want to activate your Bowels and Bladder" |
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This direct cholinergic agonist is good for:
Glaucoma, To induce pupillary contraction, To decrease intraocular pressure |
Carbachol
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This direct cholinergic agonist is used as a challenge test for dx of asthma?
Which receptors in particular does it stimulate? |
Methacholine
M3 |
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This INDIRECT cholinergic agonist can be used for:
Postoperative and neurogenic ileus, Urinary Retention, Myasthenia Gravis, Reversal of Post-op NMJ blockade 1 Unique thing about this drug? |
Neostigmine
DOES NOT cross CNS |
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This drug can be used to Tx Myasthenia Gravis LONG TERM!
This drug does NOT do what? |
Pyridostigmine
(My Pyramids will last a LONG time) Does not penetrate CNS |
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This Indirect Cholinergic Agonist (ACHesterase Inhib) has very short FX in myasthenia gravis, and TF can be used to Dx Myasthenia gravis?
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Edrophonium
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This indirect cholinergic agonist (ACHesterase inhib) can be used to tx:
Glaucoma, Atropine Overdose Another Indirect Cholinergic agonist that ONLY Tx glaucoma? |
Physostigmine
Echothiophate |
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This indirect cholinergic agonist can be used to tx Alzheimer's
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Donepezil
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Which 2 direct cholinergic agonists are resistant to AChesterase?
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Bethanechol;
Pilocarpine |
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3 Muscarinic (PNS) Antags that cause mydriasis and cycloplegia of the eye?
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Atropine,
Homatropine, Tropicamide |
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1 Muscarinic Antag that can be used to tx parkinson's dz?
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Benztropine
"PARK my BENZ" |
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Bethanechol
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Direct Cholinergic Agonist
"i'll be DIRECT, BETHANy CARbone's PILlow has seen all the METS" |
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Carbachol
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Direct Cholinergic Agonist
"i'll be DIRECT, BETHANy CARbone's PILlow has seen all the METS" |
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Pilocarpine
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Direct Cholinergic Agonist
"i'll be DIRECT, BETHANy CARbone's PILlow has seen all the METS" |
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Methacholine
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Direct Cholinergic Agonist
"i'll be DIRECT, BETHANy CARbone's PILlow has seen all the METS" |
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All direct cholinergic agonists
Direct Cholinergic Agonist "i'll be DIRECT, BETHANy CARbone's PILlow has seen all the METS" |
Bethanechol
Carbachol Pilocarpine Methacholine |
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Neostigmine
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Indirect Cholinergic Agonists
(AChesterase Inhibs) "INDIRECTLY, NEO PrEferred PEDs" |
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Pyridostigmine
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Indirect Cholinergic Agonists
(AChesterase Inhibs) "INDIRECTLY, NEO PrEferred PEDs" |
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Edrophonium
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Indirect Cholinergic Agonists
(AChesterase Inhibs) "INDIRECTLY, NEO PrEferred PEDs" |
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Physostigmine
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Indirect Cholinergic Agonists
(AChesterase Inhibs) "INDIRECTLY, NEO PrEferred PEDs" |
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Echothiophate
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Indirect Cholinergic Agonists
(AChesterase Inhibs) "INDIRECTLY, NEO PrEferred PEDs" |
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Donepezil
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Indirect Cholinergic Agonists
(AChesterase Inhibs) "INDIRECTLY, NEO PrEferred PEDs" |
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Name the Indirect Cholinergic Agonists
(AChesterase Inhibs) |
"INDIRECTLY, NEO PrEferred PEDs"
Neostigmine Pyridostigmine Edrophonium Physostigmine Echothiophate Donepezil |
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Insectisides -->
Organophosphate Poisoning (ACHesterase Inhibs)--> what sx? Antidote? MOA of Pralidoxine? |
DUMBBELSS
Diarrhea Urination Miosis Bronchospasm Bradycardia Excitation of skeletal muscle & CNS Lacrimation Sweating Salivation Atropine + Pralidoxine Increases amt ACHesterase |
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Atropine
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Muscarinic (PNS) Antag
EYE |
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Homatropine
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Muscarinic (PNS) Antag
EYE |
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Tropicamide
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Muscarinic (PNS) Antag
EYE |
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Benztropine
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Muscarinic (PNS) Antag
CNS |
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Scopolamine
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Muscarinic (PNS) Antag
CNS |
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Ipratroprium
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Muscarinic (PNS) Antag
Resp |
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Oxybutynin
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Muscarinic (PNS) Antag
GU |
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Glycopyrrolate
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GU
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Methscopoloamine
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Muscarinic (PNS) Antag
GI |
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Pirenzepine
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Muscarinic (PNS) Antag
GI |
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Propantheline
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Muscarinic (PNS) Antag
GI |
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Too much atropine -->
Too much antag of PNS --> Too much SNS --> What sx? |
Hot as a hare- hyperthermia
Dry as a bone- dry mouth, urinary ret Red as a beet- flushing Blind as a bat- cycloplegia Mad as a hatter- delirium |
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11 Direct Adrenregic Agonists
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"ENI Doctors Doing Phree directing and acting. the MAST seems Right"
Epi NE Isoproterenol Dopamine Dobutamine Phenylephrine Metaproterenol Albuterol Salmeterol Terbutaline |
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Epi
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Direct Adrenergic Ag
a1, a2, b1, b2 |
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NE
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Direct Adrenergic Ag
a1, a2, b1 |
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Isoproterenol
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Direct Adrenergic Ag
b1, b2 |
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Dopamine
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Direct Adrenergic Ag
a1 (HD), a2 (HD), b1 (MD), b2 (MD), D1 (LD) |
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Dobutamine
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Direct Adrenergic Ag
a1, a2, MOSTLY b1, b2 |
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Phenylephrine
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Direct Adrenergic Ag
a1, a2 |
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Metaproterenol
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Direct Adrenergic Ag
b1, b2 |
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Albuterol
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Direct Adrenergic Ag
b1, b2 |
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Salmeterol
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Direct Adrenergic Ag
b1, b2 |
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Terbutaline
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Direct Adrenergic Ag
b1, b2 |
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Ritrodine
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Direct Adrenergic Ag
b2 |
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3 Indirect adrenergic ags
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"otm: i can ACE indirect"
Amphetamine Ephedrine Cocaine |
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Amphetamine
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Indirect adrenergic ag
Release stored catecholamines |
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Name 2 Sympathoplegics (Inhib SNS)
& how they work |
Clonidine
a-methyldopa a2 agonist |
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Clonidine
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Sympathoplegic a2 agonist
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a-methyldopa
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Sympathoplegic a2 agonist
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Phenoxybenzamine
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Irreversible non-selective alpha receptor blocker
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Phentolamine
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Reversible non-selective alpha receptor blocker
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2 non-selective alpha receptor blockers
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Phenoxybenzamine (irreversible)
Phentolamine (Reversible) |
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Three a1 selective alpha receptor blockers?
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Prazosin
Terazosin Doxazosin |
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Prazosin
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a1 selective alpha receptor blocker
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Terazosin
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a1 selective alpha receptor blocker
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Doxazosin
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a1 selective alpha receptor blocker
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Mirtazapine
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a2 receptor blocker
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5 b1 selective receptor blockers?
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A BEAM of beta-1 blockers
Acebutolol Betaxolol Esmolol Atenolol Metoprolol |
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Acebutolol
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b1 receptor blocker
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Betaxolol
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b1 receptor blocker
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Esmolol
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b1 receptor blocker
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Atenolol
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b1 receptor blocker
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Metoprolol
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b1 receptor blocker
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4 Non-selective beta blockers?
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Please Try NOT being Picky
Propranolol Timolol Nadolol Pindolol |
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Propranolol
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Non-selective beta blocker
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Timolol
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Non-selective beta blocker
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Nadolol
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Non-selective beta blocker
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Pindolol
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Non-selective beta blocker
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2 Non-selective vasodilatory alpha & beta receptor blockers?
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Carvedilol
Labetalol |
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Carvedilol
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Non-selective vasodilatory alpha & beta receptor blocker
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Labetalol
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Non-selective vasodilatory alpha & beta receptor blocker
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2 Partial beta blockers?
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PAPA
Pindolol Acebutolol |
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Pindolol
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Partial beta blockers
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Acebutolol
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Partial beta blockers
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ANS Pharm
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ANS Pharm
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This direct cholinergic agonist is a potent stimulator of sweat, tears and saliva?
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Pilocarpine
"You cry drool and sweat on your PILow" |
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1 Muscarinic Antag that can be used for motion sickness?
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Scopolamine
(Scallop Fishing Boat) |
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1 Muscarinic Antag that can be used for Asthma & COPD?
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Ipratroprium
"I PRAY i can breathe soon) |
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2 Muscarinic Antags that will reduce bladder spasm and urgency in mild cystitis?
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Oxybutynin
Glycopyrrolate "if you get OXY clean Glenn says you'll have so much sex that you'll get a GU infxn" |
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3 Muscarinic Antags that can be used for peptic ulcer tx?
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Methscopolamine,
Pirenzepine, Propantheline |
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What is the major drug for organophosphate poisoning and how does it work?
What is it given with? |
Pralidoxime
Regenerates ACHesterase Atropine |
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Atropine is a muscarinic antag that does not only produce mydriasis and cycloplegia, but also can tx what heart cond'n?
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Bradycardia
(Think of your ACLS!) |
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What is the FX of Atropine on:
1) Eye: 2) Airway: 3) Stomach: 4) Gut: 5) Bladder: |
1) Mydriasis, Cycloplegia
2) Dec secretions 3) Dec acid secretion 4) Dec motility 5) Dec Urgency in cystitis |
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Atropine OD --> block of PNS -->
Too much SNS --> what? |
Hot as a hare,
Dry as a bone, Red as a beet, Blind as a bat, Mad as a hatter Hyperthermia (no sweating!) Urinary retention, dry mouth Flushing Cycloplegia, Mydriasis Delirium |
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Atropine can be used to block too much PNS. Too much PNS --> what sx?
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DUMBBELSS
Diarrhea Urination Miosis Bronchospasm Bradycardia Excitation of Sk. Muscle and CNS Lacrimation Sweating Salivation |
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Which direct acting adrenergic agonist can be used for:
Anaphylaxis, Glaucoma (Open Angle), Asthma, HTN |
Epi
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Which direct adrenergic agonist can be used for HYPO-TN but will cause dec renal perfusion?
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NE
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Which direct adrenergic agonist will cause AV block?
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Isoproterenol
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Which adrenergic agonist will tx:
shock --> dec renal perfusion, heart failure bc of of its positive inotropic and chronotropic FX, and is D1> beta > alpha |
Dopamine
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Which direct adrenergic agonist can be used to tx Heart failure
AND can be used for cardiac stress testing AND has inotropic but NOT chronotropic FX |
Dobutamine
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Which direct adrenergic agonist is used for nasal decongestion (a1),
and causes vasoconstriction and mydriasis? |
Phenylephrine
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Which 2 direct adrenergic agonists can be use to tx acute asthma?
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Metaproterenol
Albuterol |
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Which direct adrenergic agonist can be used to tx long term asthma?
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Salmeterol
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Which direct adrenergic agonist will reduce premature uterine contractions
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Ritrodine
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What are 3 indirect adrenergic agonists?
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Amphetamine
Ephedrine Cocaine "OTM: i can ACE INDIRECT" |
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Which indirect adrenergic agonist can be used to tx Narcolepsy, Obesity, ADD?
MOA? |
Amphetamine
Releases stored catecholamines |
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Which indirect adrenergic agonist can be used to tx Nasal congestion, urinary incontinence and HYPO-TN?
MOA? |
Ephedrine
Release stored catecholamines |
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Which indirect adrenergic agonist can cause vasoconstriction AND TF act as a local anesthetic?
MOA? |
Cocaine
Dopamine reuptake inhibitor |
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What are 2 Sympathoplegic Rx that inhibit the SNS?
MOA? CU? |
Clonidine & a-methyldopa
Centrally acting alpha-agonists HTN, esp w/ renal dz bc |
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Which irreversible, non-selective alpha receptor blocker can be used to tx pheochromocytoma?
2 AE? |
Phenoxybenzamine
Orthostatic HYPO-TN & Reflex Tachy |
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Which reversible, non-selective alpha receptor blocker can be used for pts on MAOIs who eat too much tyramine-containing foods?
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Phentolamine
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Which 3 alpha-1 selective receptor blockers and be used to tx:
HTN, Urinary retention in BPH 3 AEs of these 3 drugs? |
Prazosin, Terazosin, Doxazosin
1st DOSE ORTHOSTATIC HYPO-TN, dizziness, HA |
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MOA of mirtazapine (alpha-2 selective receptor blocker)?
3 AEs? |
Mirtazapine
Sedation Inc Serum Cholesterol Inc Appetite |
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6 CU of the beta-blockers?
"HAM SandwiCh!? Gross! |
HTN
Angina Pectoris MI SVT (Propranolol, Esmolol) CHF Glaucoma |
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5 AEs of beta-blockers?
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Impotence,
Exacerbation of asthma, Cautious use in Diabetics, Adverse CV FX (brady, av block, CHF), Adverse CNS FX (Sedation, Sleep alteration) |
