Boards Microbio

Front 1

gram + rods (5)

Back 1

clostridium, cornybacterium, bacillus, listeria, mycobacterium

Front 2

gram - coccus (1)

Back 2

Neisseria

Front 3

spirochetes (3)

Back 3

leptospiria, borrelia, treponema

Front 4

don't stain well (6)

Back 4

treponema (too thin), ricketsiae (intracellular), chlamydia (intracellular), mycoplasma (no cell wall), mycobacterium (high lipid content), legionella pneumophilia (mostly intracellular)

Front 5

media for H flu

Back 5

chocolate agar with factors 5 and 10

Front 6

media for N. gonorrhoeae

Back 6

thayer martin

Front 7

media for B. pertussis

Back 7

Bordet-Gengou (potato) agar

Front 8

media for C. diptheriae

Back 8

tellurite plate, Lofflers media

Front 9

media for TB

Back 9

Lowenstein jensen agar

Front 10

media for mycoplasma pneumoniae

Back 10

Eaton's agar

Front 11

media for E. Coli

Back 11

eosin methylene blue

Front 12

media for legionella

Back 12

charcoal yeast with Fe and cysteine

Front 13

media for fungi

Back 13

sabourauds agar

Front 14

obligate aerobes (4)

Back 14

pseudomonas, nocardia, TB, bacillus

Front 15

obligate anaerobes (3)

Back 15

clostridium, bacterioides, actinomyces (lack catalase or superoxide dismutase)

Front 16

obligate intracellular (2)

Back 16

ricketsiae and chlamydia

Front 17

facultative intracellular (8)

Back 17

legionella, TB, listeria, neiserria, salmonella, franciella, yersinia, brucella

Front 18

who secretes IgA protease

Back 18

h. flu, s. pneumo, neiserria

Front 19

cAMP inducers (4)

Back 19

pertussis (inactivates Gi), E. coli (activates Gs), cholera (activates Gs) and anthrax (toxin is an adenylate cyclase)

Front 20

lysogenic phage encoded toxins (5)

Back 20

Shiga A like toxin, botulinum toxin, cholera toxin, diptheria toxin, erythrogenic toxin of S. pyogenes

Front 21

staph aureus (5)

Back 21

catalase +, coagulase +, b (complete) hemolysis, ferments mannitol, common colonizer of the oropharynx

Front 22

staph epidermidis (4)

Back 22

catalase +, coagulase -, novobiacin sensitive, makes a biofilm

Front 23

staph saprophyticus (3)

Back 23

catalase +, coagulase -, novobiacin resistant

Front 24

strep pneumo (6)

Back 24

catalase -, a (partial) hemolysis, optochin sensitive, bile soluble, lancet shaped diplococcus, rusty sputum

Front 25

strep viridans (4)

Back 25

catalase -, a (partial) hemolytic, optichin resistant, not bile soluble

Front 26

group A strep (3)

Back 26

pyogenes; catalase -, b (complete) hemolysis, bactitracin sensitive

Front 27

group B strep (4)

Back 27

agalactiae; catalase -, b (complete) hemolysis, bactitracin resistant, +CAMP test

Front 28

enterococcus (2+4)

Back 28

catalase -, variable hemolysis, can grow on 6.5% NaCl, cause UTI and subacute endocarditis, vanco-resistant are important cause of nosocomial infection

Front 29

strep pneumo is most common cause of what (4)

Back 29

meningitis, otitis media (in kids), pneumonia, sinusitis

Front 30

treatment for C. difficile

Back 30

metronidazole

Front 31

only bacteria with protein capsule, structure on culture

Back 31

b. anthracis, forms serpantine strands on culture

Front 32

only gram + with an endotoxin

Back 32

listeria monocytogenes

Front 33

location for primary TB

Back 33

granulomas in the lower part of middle lobes, near the periphery (Gohn focus), also hilar LNs (together are complex)

Front 34

location for secondary TB

Back 34

upper lobes, form cavitary lesions due to cytokine release

Front 35

what does the diptheria vaccine induce

Back 35

IgG against the toxin

Front 36

E Coli toxins stimulate what

Back 36

Labile toxin: stimulates adenylate cyclase; Stable: stmulates guanylate cyclase; labile like the Air, stable like the Ground

Front 37

shiga toxin

Back 37

cleaves host cell rRNA (inactivates 60s); also enhances cytokine release causing HUS (E.Coli has same property)

Front 38

MRSA

Back 38

resistant to B-lactams due to altered PBP

Front 39

what makes Viridins pathogenic

Back 39

produce an insoluble EC polysaccaharide (dextrans) from sucrose, which allows them to tightly adhere to fibrin-platelet aggregates, this is why people often get these infections after dental procedures

Front 40

what makes mutans pathogenic

Back 40

produces acid which destroys enamel and causes cavities

Front 41

scarlet fever

Back 41

caused by Strep pyogenes; pharyngitis, tonsilitis, glossitis, rash on skin and tongue; due to pyogenic exotoxin which is encoded for on lysogenic phage

Front 42

M protein

Back 42

produced by Pyogenes, helps prevent phagocytosis and is cytotoxic to PMNs; immune response to this can lead to rheumatic fever

Front 43

diptheria (3)

Back 43

exotoxin via prophage, inhibits protein synthesis via ADP ribo of EF-2, contain granules, club shaped

Front 44

component of spores

Back 44

dipicolonic acid

Front 45

tetanus vaccine

Back 45

leads to production of Ab's which neutralize the toxin

Front 46

C perfringes

Back 46

produceds a-toxin (lecithinase, splits lipids) that can cause myonecrosis (gas gangrene)

Front 47

treatment for listeria

Back 47

ampicillin, not susceptiple to cephalosporins

Front 48

what is in the PPD

Back 48

tuberculin (outer surface protein) plus mycolic acids

Front 49

Leprosy

Back 49

granuloma formation (incl multinuc giant cells), likes cool temps (infects skin and superficial nerves); lepromatous is worse (failed cell mediated, Th1, immunity),causes loss of eyebrows, nasal colapse, lumpy earlobe; tuberculoid is self limited

Front 50

Neisseria fermenters and catalase

Back 50

Meningitidis: maltose and glucose; gonorrhea: glucose only; are catalase +

Front 51

lactose fermenters

Back 51

grow pink on MacConkey's; Klebsiella, E. Coli, Enterobacter, Serratia

Front 52

what does H. influenzae cause (4)

Back 52

pneumonia, meningitis, otitis media, epiglottitis

Front 53

H. flu vaccine

Back 53

contains polysaccharide capsule (polyribotol-P) conjugated to diptheria toxoid or other protein (to allow for class switching)

Front 54

Legionnaires dz

Back 54

caused by Legionella pneumo, severe pneumonia (high fever, diarrhea, cough, confusion, often in smoker)

Front 55

what do you get Legionella infections from

Back 55

water source

Front 56

what does P. aeurginosa cause (7)

Back 56

wound and burn infections, pneumonia (esp in CF), septicemia, external otitis (swimmers ear), UTI (esp in pts with in dwelling catheters), diabetic osteomyelitis, hot tub folliculitis

Front 57

id of P. aeurginosa

Back 57

gram -, non-lactose fermenter, oxidase+, blue-green pigment, grapelike odor

Front 58

treatment of P. aeurginosa

Back 58

aminoglycoside plus extended spectrum penicillin (pipercillin)

Front 59

ecthyma gangrenosum

Back 59

characteristic lesions in septicemia, black necrotic center and raised hemorrhagic outside, due to production of elastase

Front 60

what does EAEC make

Back 60

biofilm

Front 61

pathogenesis of E. Coli cause of neonatal septicemia vs. UTI

Back 61

neonatal septicemia: K1 capsule; UTI: pili

Front 62

enterobacteriaceae (7)

Back 62

Shigella, Salmonella, E. Coli, enterobacter, klebsiella, proteus, serratia; are all gram-, oxidase-, ferment glucose; also have O Ag (polysaccharide of endotoxin), K Ag (related to virulence), H flagellar Ag in motile species

Front 63

klebsiella

Back 63

gram-, lactose fermenter, has thick capsule and so produces a mucoid sputum, cavitate in upper lobes, current jelly sputum, pneumo in alcoholics and diabetics

Front 64

Salmonella

Back 64

gram-, oxidase-, non-lactose fermenter, capsule, produce H2S, have flagella; invade intestinal mucosa and cause blood diarrhea, most have animal resevoir

Front 65

salmonella typhi

Back 65

thyphoid fever; diarrhea, HA, rose spots on abdomen, hepatosplenomegaly; can remain in gallbladder chronically

Front 66

shigella

Back 66

gram-, non-lactose fermenter, oxidase-, very virulent (adapted to survive in acidic stomach), propel themselves within a cell by actin polymerization

Front 67

spirochetes

Back 67

borrelia, leptospira, treponema