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4 Cards in this Set
- Front
- Back
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Mtb with inactive catalase-peroxidase
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isoniazid requires activation by mtb catalase peroxidase before it can inhibit mycolic acid synth
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arabinsyl transferase
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inactivated by ethambutol
increased production of arabinsyl transferase confers ethambutol resistance to Mtb |
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Isoniazid resistance
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isoniazid requires activation by mtb catalase peroxidase before it can inhibit mycolic acid synth
(other?) resistence genes: katG, inhA, ndh |
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ethambutol resistence
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arabinsyl transferase inactivated by ethambutol
↑ production of arabinsyl transferase confers ethambutol resistance to Mtb embCAB gene (same/different?) |
