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92 Cards in this Set

  • Front
  • Back
eye movement abnormaliities localize to ___ (2) of cerebellum
vermis
flocculonodular lobe
2 lobes of cerebellum
they are separated by ___
anterior
posterior
primary fissure
___ fissure is visible only on ventral surface of cerebellum
posterolateral
posterolateral fissure separates ___ from ___
flocculonodular lobes
posterior lobe
flocculus is medial/lateral to nodulus
the 2 are connected via ___
lateral
pedicles
tonsillar herniation is bad because of ___
compression of medulla, compromising respiratory centers
superior cerebellar peduncle decussates at level of ___
it primarily carries ___
it is aka ___
inferior colliculi
cerebellar outputs
brachium conjunctivum
middle cerebellar peduncle primarily carries ___
it is aka ___
cerebellar inputs
brachium pontis
inferior cerebellar peduncle primarily carries ___
it is aka ___
cerebellar inputs
restiform body
3 functional regions of cerebellum
lateral hemispheres
intermediate hemispheres
vermis/flocculonodular lobe
lateral hemispheres do ___
motor planning for extremities
intermediate hemispheres do ___
appendicular coordination
vermis/flocculonodular lobes do ___ (2)
axial coordination
vestibulo-ocular coordination
deep cerebellar nuclei from lateral to medial
___ are largest
dentate
emboliform
globose
fastigial
dentate
___ comprise the interposed nuclei
emboliform
globose
___ is active before voluntary movements
___ is active during voluntary movements
dentate
interposed
dentate nuclei receive inputs from ___
lateral cerebellar hemispheres
interposed nuclei receive inputs from ___
intermediate cerebellar hemispheres
fastigial nuclei receive inputs from ___
vermis
flocculonodular lobe
cerebellar cortex has ___ layers
3
3 layers of cerebellar cortex from deep to superficial
granule cell layer
purkinje cell layer
molecular layer
molecular layer contains ___ (3)
granule cell axons
purkinje cell dendrites
interneurons
2 kinds of cerebellar input fiber types
mossy fibers
climbing fibers
mossy fibers synapse on ___s
granule cells
granule cell axons give off ___s in the molecular layer
parallel fibers
parallel fibers run in plane of ___ and perpendicular to ___, with which they synapse
surface of folium
dendrites of purkinje cells
synapses from parallel fibers to purkinje cells are excitatory/inhibitory
excitatory
purkinje cells synapse on ___s
deep nuclei
synapses from purkinje cells on deep nuclei are excitatory/inhibitory
inhibitory
climbing fibers start in ___
contralateral inferior olivary nucleus
climbing fibers grow along axon of ___
purkinje cell
climbing fibers synapse on approximately ___ purkinje cells
10
synapse from climbing fiber on purkinje cell is excitatory/inhibitory
excitatory
each purkinje cells receives synapses from ___ climbing fibers
1
3 kinds of cerebellar interneurons
stellate
Golgi
basket
stellate cells are located in ___ layer
Golgi cells are located in ___ layer
basket cells are located in ___ layer
molecular
granule cell
molecular
basket fibers have dendrites oriented ___ly
their axons terminate on ___
this does ___
perpendicular to parallel fibers of molecular layer
purkinje cells
lateral inhibition of purkinje cells
golgi cells receive inputs from ___
their axons terminate on ___
this does ___
parallel fibers of molecular layer
granule cells
feedback inhibition on granule cells
cerebellar glomeruli are located in ___ layer
granule cell
cerebellar glomeruli have ___ (2) as inputs and ___ as terminus
mossy fiber
golgi cell axon
granule cell dendrite
on microscopy, cerebellar glomeruli look like ___s
clearings among granule cells
lesions of ___ cerebellum cause ipsilateral deficit because of ___
lateral and intermediate
both input and output pathways involve double decussation
all cerebellar output pathways project to ___ (2)
cortex
medulla
cerebellar outputs project to cortex through ___
contralateral VL pars caudalis of thalamus
VL projects to ___ (5) cortices
motor
premotor
SMA
parietal lobe
PFC
lateral and intermediate cerebellar output projects to medulla through ___
contralateral red nucleus
lateral cerebellar outputs all project through ___
dentate nucleus
lateral cerebellar outputs project from dentate nucleus to medulla through ___
parvocellular red nucleus
parvocellular red nucleus is the ___ part
rostral
intermediate cerebellar outputs all project through ___
interposed nuclei
intermediate cerebellar outputs project to medulla through ___
magnocellular red nucleus
magnocellular red nucleus gives rise to ___
rubrospinal tract
parvocellular red nucleus projects to ___ in medulla via ___
inferior olivary nucleus
central tegmental tract
first neuron in triangle of Guillain-Mollaret has soma in ___ and projects to ___
lateral cerebellum
dentate nucleus
2nd neuron in triangle of Guillain-Mollaret has soma in ___ and projects vis ___ to ___
dentate nucleus
superior cerebellar peduncle
contralateral parvocellular red nucleus
3rd neuron in triangle of Guillain-Mollaret has soma in ___ and projects via ___ to ___
parvocellular red nucleus
central tegmental tract
inferior olivary nucleus
4th neuron in triangle of Guillain-Mollaret has soma in ___ and projects via ___ to ___
inferior olivary nucleus
inferior cerebellar peduncle (climbing fibers)
contralateral lateral cerebellum
triangle of Guillain-Mollaret is aka ___
myoclonic triangle
lesion of triangle of Guillain-Mollaret can cause ___ which presents with ___
hypertrophic olivary degeneration
palatal myoclonus
T/F: projections from lateral and intermediate cerebellum go to distinct parts of VL
true
2 kinds of medial cerebellar outputs
superior vermis
inferior vermis + flocculonodular lobe
cerebellar outputs from superior vermis all project through ___
fastigial nuclei
cerebellar outputs from superior vermis project to ipsilateral medulla via ___ and contralateral medulla via ___
juxtarestiform body
uncinate fasciculus
superior vermis projects to ___ in ipsilateral medulla
vestibular nuclei
reticular formation
superior vermis projects to ___ in contralateral medulla
vestibular nuclei
juxtarestiform body is visible at ___
lateral wall of 4th ventricle
inferior cerebellum and flocculonodular lobe all project via ___ to ___
juxtarestiform body
ipsilateral vestibular nuclei
T/F: no cerebellar outputs project to lower motor neurons
false: some fastigial projection to upper C cord
all cerebellar inputs except those from ___ are via ___
inferior olivary nuclei
mossy fibers
cerebellar inputs from inferior olivary nucleus are carried via ___
climibing fibers
cortical inputs to cerebellum project first to ___
ipsilateral pontine nuclei
pontine nuclei project to contralateral cerebellum via ___
middle cerebellar peduncle
spinal inputs to cerebellum travel via ___
spinocerebellar tracts
4 spinocerebellar tracts
dorsal SCT
cuneocerebellar tract
ventral SCT
rostral SCT
dorsal SCT carries inputs from ___
leg proprioceptors
ventral SCT carries inputs from ___
leg interneurons
rostral SCT carries inputs from ___
arm interneurons
cuneocerebellar tract carries inputs from ___
arm proprioceptors
soma of 1st neuron in dorsal SCT is in ___
it projects to ___ (2)
leg DRG proprioceptor
fasciculus gracilis
nucleus dorsalis of clark
nucleus dorsalis of clark is located at ___ (on axial slice)
its rostro-caudal extent is from ___ to ___
antero-medial aspect of posterior grey horn
C8
L2 or L3
soma of 2nd neuron in dorsal SCT is in ___
it projects via ___ to ___
nucleus dorsalis of clark
inferior cerebellar peduncle
ipsilateral cerebellar cortex
in spinal cord, dorsal SCT runs in the ___
dorsolateral funiculus
soma of 1st neuron in cuneocerebellar tract is in ___
it projects via ___ to ___
arm DRG proprioceptor
fasciculus cuneatus
external nucleus cuneatus
soma of 2nd neuron in cuneocerebellar tract is in ___
it projects via ___ to ___
external nucleus cuneatus
inferior cerebellar peduncle
ipsilateral cerebellar cortex
soma of 1st neuron in ventral SCT tract is in ___ (2)
it projects via ___ to ___
spinal border cells
intermediate zone
superior cerebellar peduncle
ipsilateral cerebellar cortex
spinal border cells are located in ___
outer edge of central grey
ventral SCT decussates at ___
AWC and after entering cerebellum via superior peduncle
anterior aspect of cerebellum is primarily perfused by ___
AICA
posterior cerebellum is primarily perfused by ___
SCA and PICA
cerebellar infarcts occur primarily in ___ (2) territories
SCA
PICA
cerebellar infarcts sparing the brainstem are primarily in ___ territory
SCA
5 extra-cerebellar lesions which cause ataxia (or similar symptoms)
pons
PFC
lacunar ataxia hemiparesis
dorsal column (sensory ataxia)
other SC