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92 Cards in this Set
- Front
- Back
eye movement abnormaliities localize to ___ (2) of cerebellum
|
vermis
flocculonodular lobe |
|
2 lobes of cerebellum
they are separated by ___ |
anterior
posterior primary fissure |
|
___ fissure is visible only on ventral surface of cerebellum
|
posterolateral
|
|
posterolateral fissure separates ___ from ___
|
flocculonodular lobes
posterior lobe |
|
flocculus is medial/lateral to nodulus
the 2 are connected via ___ |
lateral
pedicles |
|
tonsillar herniation is bad because of ___
|
compression of medulla, compromising respiratory centers
|
|
superior cerebellar peduncle decussates at level of ___
it primarily carries ___ it is aka ___ |
inferior colliculi
cerebellar outputs brachium conjunctivum |
|
middle cerebellar peduncle primarily carries ___
it is aka ___ |
cerebellar inputs
brachium pontis |
|
inferior cerebellar peduncle primarily carries ___
it is aka ___ |
cerebellar inputs
restiform body |
|
3 functional regions of cerebellum
|
lateral hemispheres
intermediate hemispheres vermis/flocculonodular lobe |
|
lateral hemispheres do ___
|
motor planning for extremities
|
|
intermediate hemispheres do ___
|
appendicular coordination
|
|
vermis/flocculonodular lobes do ___ (2)
|
axial coordination
vestibulo-ocular coordination |
|
deep cerebellar nuclei from lateral to medial
___ are largest |
dentate
emboliform globose fastigial dentate |
|
___ comprise the interposed nuclei
|
emboliform
globose |
|
___ is active before voluntary movements
___ is active during voluntary movements |
dentate
interposed |
|
dentate nuclei receive inputs from ___
|
lateral cerebellar hemispheres
|
|
interposed nuclei receive inputs from ___
|
intermediate cerebellar hemispheres
|
|
fastigial nuclei receive inputs from ___
|
vermis
flocculonodular lobe |
|
cerebellar cortex has ___ layers
|
3
|
|
3 layers of cerebellar cortex from deep to superficial
|
granule cell layer
purkinje cell layer molecular layer |
|
molecular layer contains ___ (3)
|
granule cell axons
purkinje cell dendrites interneurons |
|
2 kinds of cerebellar input fiber types
|
mossy fibers
climbing fibers |
|
mossy fibers synapse on ___s
|
granule cells
|
|
granule cell axons give off ___s in the molecular layer
|
parallel fibers
|
|
parallel fibers run in plane of ___ and perpendicular to ___, with which they synapse
|
surface of folium
dendrites of purkinje cells |
|
synapses from parallel fibers to purkinje cells are excitatory/inhibitory
|
excitatory
|
|
purkinje cells synapse on ___s
|
deep nuclei
|
|
synapses from purkinje cells on deep nuclei are excitatory/inhibitory
|
inhibitory
|
|
climbing fibers start in ___
|
contralateral inferior olivary nucleus
|
|
climbing fibers grow along axon of ___
|
purkinje cell
|
|
climbing fibers synapse on approximately ___ purkinje cells
|
10
|
|
synapse from climbing fiber on purkinje cell is excitatory/inhibitory
|
excitatory
|
|
each purkinje cells receives synapses from ___ climbing fibers
|
1
|
|
3 kinds of cerebellar interneurons
|
stellate
Golgi basket |
|
stellate cells are located in ___ layer
Golgi cells are located in ___ layer basket cells are located in ___ layer |
molecular
granule cell molecular |
|
basket fibers have dendrites oriented ___ly
their axons terminate on ___ this does ___ |
perpendicular to parallel fibers of molecular layer
purkinje cells lateral inhibition of purkinje cells |
|
golgi cells receive inputs from ___
their axons terminate on ___ this does ___ |
parallel fibers of molecular layer
granule cells feedback inhibition on granule cells |
|
cerebellar glomeruli are located in ___ layer
|
granule cell
|
|
cerebellar glomeruli have ___ (2) as inputs and ___ as terminus
|
mossy fiber
golgi cell axon granule cell dendrite |
|
on microscopy, cerebellar glomeruli look like ___s
|
clearings among granule cells
|
|
lesions of ___ cerebellum cause ipsilateral deficit because of ___
|
lateral and intermediate
both input and output pathways involve double decussation |
|
all cerebellar output pathways project to ___ (2)
|
cortex
medulla |
|
cerebellar outputs project to cortex through ___
|
contralateral VL pars caudalis of thalamus
|
|
VL projects to ___ (5) cortices
|
motor
premotor SMA parietal lobe PFC |
|
lateral and intermediate cerebellar output projects to medulla through ___
|
contralateral red nucleus
|
|
lateral cerebellar outputs all project through ___
|
dentate nucleus
|
|
lateral cerebellar outputs project from dentate nucleus to medulla through ___
|
parvocellular red nucleus
|
|
parvocellular red nucleus is the ___ part
|
rostral
|
|
intermediate cerebellar outputs all project through ___
|
interposed nuclei
|
|
intermediate cerebellar outputs project to medulla through ___
|
magnocellular red nucleus
|
|
magnocellular red nucleus gives rise to ___
|
rubrospinal tract
|
|
parvocellular red nucleus projects to ___ in medulla via ___
|
inferior olivary nucleus
central tegmental tract |
|
first neuron in triangle of Guillain-Mollaret has soma in ___ and projects to ___
|
lateral cerebellum
dentate nucleus |
|
2nd neuron in triangle of Guillain-Mollaret has soma in ___ and projects vis ___ to ___
|
dentate nucleus
superior cerebellar peduncle contralateral parvocellular red nucleus |
|
3rd neuron in triangle of Guillain-Mollaret has soma in ___ and projects via ___ to ___
|
parvocellular red nucleus
central tegmental tract inferior olivary nucleus |
|
4th neuron in triangle of Guillain-Mollaret has soma in ___ and projects via ___ to ___
|
inferior olivary nucleus
inferior cerebellar peduncle (climbing fibers) contralateral lateral cerebellum |
|
triangle of Guillain-Mollaret is aka ___
|
myoclonic triangle
|
|
lesion of triangle of Guillain-Mollaret can cause ___ which presents with ___
|
hypertrophic olivary degeneration
palatal myoclonus |
|
T/F: projections from lateral and intermediate cerebellum go to distinct parts of VL
|
true
|
|
2 kinds of medial cerebellar outputs
|
superior vermis
inferior vermis + flocculonodular lobe |
|
cerebellar outputs from superior vermis all project through ___
|
fastigial nuclei
|
|
cerebellar outputs from superior vermis project to ipsilateral medulla via ___ and contralateral medulla via ___
|
juxtarestiform body
uncinate fasciculus |
|
superior vermis projects to ___ in ipsilateral medulla
|
vestibular nuclei
reticular formation |
|
superior vermis projects to ___ in contralateral medulla
|
vestibular nuclei
|
|
juxtarestiform body is visible at ___
|
lateral wall of 4th ventricle
|
|
inferior cerebellum and flocculonodular lobe all project via ___ to ___
|
juxtarestiform body
ipsilateral vestibular nuclei |
|
T/F: no cerebellar outputs project to lower motor neurons
|
false: some fastigial projection to upper C cord
|
|
all cerebellar inputs except those from ___ are via ___
|
inferior olivary nuclei
mossy fibers |
|
cerebellar inputs from inferior olivary nucleus are carried via ___
|
climibing fibers
|
|
cortical inputs to cerebellum project first to ___
|
ipsilateral pontine nuclei
|
|
pontine nuclei project to contralateral cerebellum via ___
|
middle cerebellar peduncle
|
|
spinal inputs to cerebellum travel via ___
|
spinocerebellar tracts
|
|
4 spinocerebellar tracts
|
dorsal SCT
cuneocerebellar tract ventral SCT rostral SCT |
|
dorsal SCT carries inputs from ___
|
leg proprioceptors
|
|
ventral SCT carries inputs from ___
|
leg interneurons
|
|
rostral SCT carries inputs from ___
|
arm interneurons
|
|
cuneocerebellar tract carries inputs from ___
|
arm proprioceptors
|
|
soma of 1st neuron in dorsal SCT is in ___
it projects to ___ (2) |
leg DRG proprioceptor
fasciculus gracilis nucleus dorsalis of clark |
|
nucleus dorsalis of clark is located at ___ (on axial slice)
its rostro-caudal extent is from ___ to ___ |
antero-medial aspect of posterior grey horn
C8 L2 or L3 |
|
soma of 2nd neuron in dorsal SCT is in ___
it projects via ___ to ___ |
nucleus dorsalis of clark
inferior cerebellar peduncle ipsilateral cerebellar cortex |
|
in spinal cord, dorsal SCT runs in the ___
|
dorsolateral funiculus
|
|
soma of 1st neuron in cuneocerebellar tract is in ___
it projects via ___ to ___ |
arm DRG proprioceptor
fasciculus cuneatus external nucleus cuneatus |
|
soma of 2nd neuron in cuneocerebellar tract is in ___
it projects via ___ to ___ |
external nucleus cuneatus
inferior cerebellar peduncle ipsilateral cerebellar cortex |
|
soma of 1st neuron in ventral SCT tract is in ___ (2)
it projects via ___ to ___ |
spinal border cells
intermediate zone superior cerebellar peduncle ipsilateral cerebellar cortex |
|
spinal border cells are located in ___
|
outer edge of central grey
|
|
ventral SCT decussates at ___
|
AWC and after entering cerebellum via superior peduncle
|
|
anterior aspect of cerebellum is primarily perfused by ___
|
AICA
|
|
posterior cerebellum is primarily perfused by ___
|
SCA and PICA
|
|
cerebellar infarcts occur primarily in ___ (2) territories
|
SCA
PICA |
|
cerebellar infarcts sparing the brainstem are primarily in ___ territory
|
SCA
|
|
5 extra-cerebellar lesions which cause ataxia (or similar symptoms)
|
pons
PFC lacunar ataxia hemiparesis dorsal column (sensory ataxia) other SC |