Blood Components And Component Therapy

Front 1

component making should be w/in how many hours?

Back 1

8 hours

Front 2

How do you make a platelet concentrate from a whole blood?

Back 2

light spin then hard spin

Front 3

In how many hours should an FFP be made?

Back 3

8 hours

Front 4

How do you create cryosupernate and cryoprecipitate from FFP?

Back 4

Thaw at 1-6C and centrifuge

Front 5

How do you prepare usage of FFP?

Back 5

Thaw at in a 37 celsius waterbath

Front 6

How many hours should platelets be allowed to rest before placing in agitator?

Back 6

1-2 hours

Front 7

pH needed in platelet preservation

Back 7

6.2

Front 8

the 2 types of platelet concentrate

Back 8

Random donor platelet concentrate and single donor platelet concentrate

Front 9

how many units of random donor platelet concentrate is needed to have a therapeutic effect?

Back 9

4-6

Front 10

plt refractoriness

Back 10

no increase in platelet count

Front 11

quality control in single donor platelet concentrate

Back 11

3.0x10^11 platelets/unit

Front 12

QC in RDPC

Back 12

5.5x10^10 platelets/unit

Front 13

expiration date of pooled products

Back 13

4 hours

Front 14

After thawing FFP, within how many hours must you use it?

Back 14

24 hours

Front 15

After thawing cyroprecipitate, within how many hours must you use it?

Back 15

6 hours

Front 16

Leukocyte concentration expiry date

Back 16

24 hours

Front 17

1 unit of RBC can increase hemoglobin and hematocrit by?

Back 17

1 g/dL and by 3-5%

Front 18

contains all coagulation factors

Back 18

Fresh Frozen Plasma

Front 19

QC for Factor 8 in Cryoprecipitate

Back 19

80IU

Front 20

QC For Fibrinogen in Cryoprecipitate

Back 20

250mg

Front 21

PRBC should be transfused within how many hours/minutes after obtaining?

Back 21

4 hours

Front 22

Plasma products should be transfused within how many hours/minutes after obtaining?

Back 22

20 minutes

Front 23

Storage temperature and expiry: Whole Blood

Back 23

1-6C for 35 days

Front 24

Storage temperature and expiry: PRBC irradiated unit

Back 24

1-6C for 28 days from date of irradiation

Front 25

Storage temperature and expiry: RBC

Back 25

1-6C for at most 42 days

Front 26

Storage temperature and expiry: Leukocyte poor red blood cells

Back 26

1-6C

Closed system: same for RBC

open system: 24 hours

Front 27

Storage temperature and expiry: washed RBC

Back 27

1-6C for 24 hours (open system)

Front 28

Storage temperature and expiry: frozen RBC

Back 28

-65C or -120C for 10 years

Front 29

Storage temperature and expiry: deglycerolized RBC

Back 29

for 24 hours

Front 30

Storage temperature and expiry: platelets random donor

Back 30

20-24C with continuous agitation for 3-5 days

Front 31

Storage temperature and expiry: platlets single donor

Back 31

20-24C with continuos agitation for 3-5 days

Front 32

Storage temperature and expiry: FFP

Back 32

-18C for 1 year or -65C for 7 years

Front 33

Storage temperature and expiry: Single Donor Plasma

Back 33

1-6C for up to 5 days beyond whole blood expiration date

Front 34

Storage temperature and expiry: cryoprecipitate

Back 34

-18C for 1 year

Front 35

Storage temperature and expiry: Granulocyte Concentrate

Back 35

20-24C for 24 hours

Front 36

QC for granulocyte concentrate

Back 36

1x10^10

Front 37

Blood component used: To restore oxygen carrying capacity

Back 37

whole blood or packed rbc

Front 38

Blood component used: to prevent TA-GVHD

Back 38

RBC irradiated unit

Front 39

Blood component used: washed RBC

Back 39

patients who have a history of plasma protein antibodies, diagnosis of PNH, history of frebrile reactions owing to luekoagglutinins

Front 40

Blood component used: leukocyte poor RBC

Back 40

history of reoccurring febrile reactions due to white cell antibodies

Front 41

Blood component used: platelets random donor

Back 41

to correct thrombocytopenia

Front 42

Blood component used: platelets single donor

Back 42

to correct thrombocytopenia from refractoriness

Front 43

Blood component used: FFP

Back 43

treatment of multiple coagulation factor deficiencies

Front 44

Blood component used: Single Donor Plasma

Back 44

treatment of stable clotting factor deficiency

Front 45

Blood component used: Cryoprecipitate

Back 45

Correction of Factor 8 and fibrinogen deficiency

Front 46

Blood component used: Granulocyte concentrate

Back 46

correct severe neutropenia, fever unresponsive to antibiotic therapy, and myeloid hypoplasia of the bone marrow

Front 47

High Glycerol technique freezing temperature

Back 47

-80 Celsius

Front 48

High glycerol RBC is stored at what temperature and where?

Back 48

-65 Celsius in a mechanical freezer

Front 49

Low glycerol freezing temperature

Back 49

-196 Celsius

Front 50

Low glycerol RBC stored at what temperature and where?

Back 50

-120 Celsius in liquid nitrogen

Front 51

Concentration for High Glycerol

Back 51

40%

Front 52

Concentration for Low Glycerol

Back 52

20%

Front 53

Slow freezing method for Frozen RBC

Back 53

High Glycerol

Front 54

Fast freezing method for Frozen RBC

Back 54

Low glycerol

Front 55

When is RhoGam given?

Back 55

28th week of gestation and 72 hours after birth

Front 56

Rhogam storage temp and expiry date

Back 56

1-6C for 3 years

Front 57

Deglycerolization

Back 57

Wash RBC in a hypertonic solution to isotonic solution

Front 58

1st generation filters for WBC

Back 58

Pore size is 170um and it removes fibrin clot

Front 59

2nd generation filters for WBC

Back 59

Pore size is 20-40um and it removes microaggregates

Front 60

3rd generation filters for WBC

Back 60

removes 99.9% of WBC

Front 61

US standard for QC of Leukocyte Poor RBC

Back 61

5x10^6

Front 62

Choices for AB individuals from most preferred to least preferred

Back 62

AB, A, B, O

Front 63

Final check of ABO compatibility between donor and patient

Back 63

Crossmatching

Front 64

2 phases in crossmatching

Back 64

immediate spin and antiglobulin crossmatch

Front 65

Major crossmatching

Back 65

DR PS

Donor's Red Blood cells

Patient's Serum

Front 66

Minor Crossmatching

Back 66

DS PR

Donor's serum

Patient's red cells

Front 67

Sample for crossmatching

Back 67

Serum

Front 68

Sample for crossmatching should be obtained within?

Back 68

72 hours

Front 69

Donor and recipient serum must be stored at?

Back 69

1-6C for 7 days following transfusion

Front 70

Hemolyzed samples are allowed in Crossmatching. True or False?

Back 70

FALSE

Front 71

Unused units stored in the wrong temperature must be returned within how many hours or minutes?

Back 71

30 minutes

Front 72

Patients with fever cannot be given blood transfusion. True or false?

Back 72

true. fever is a sign of transfusion reaction

Front 73

Acute immunologic transfusion reactions

Back 73

hemolytic, febrile nonhemolytic, allergic, anaphylactic shock, and TRALI

Front 74

Acute nonimmunologic transfusion reactions

Back 74

bacterial contamination, circulatory overload, and physical/chemical hemolysis

Front 75

Delayed immunologic transfusion reactions

Back 75

hemolytic, TA-GVHD, posttransfusion purpura

Front 76

Delayed nonimmunologic transfusion reactions

Back 76

transfusion-induced hemosiderosis, disease transmission

Front 77

Anti-WBCs or anti-leukocytes are associated with what transfusion reaction?

Back 77

Febrile nonhemolytic reactionA

Front 78

ABO incompatibility is associated with what transfusion reaction?

Back 78

Acute hemolytic transfusion reaction

Front 79

High IgE levels are associated with what transfusion reaction?

Back 79

Allergic reaction

Front 80

Non-cardiogenic pulmonary edema and anti-WBC is associated with what transfusion reaction?

Back 80

TRALI

Front 81

Anaphylactic reactions are associated with what immunoglobulin?

Back 81

IgA

Front 82

Most common contaminants of platelet concentrate

Back 82

Bacillus, Streptococcus, Staphylococcus

Front 83

Iatrogenic transfusion reaction

Back 83

Circulatory overload or TACO

Front 84

Kidd blood group is associated with what transfusion reaction?

Back 84

Delayed hemolytic transfusion reaction

Front 85

Anti-platelet 1 is associated with what transfusion reaction?

Back 85

posttransfusion purpura

Front 86

Most suitable urine specimen for transfusion reaction investigation

Back 86

1st voided urine after transfusion

Front 87

What do you look for in urine in transfusion reactions?

Back 87

Hemoglobinuria

Front 88

Gel Technology advantage

Back 88

requires no washing, and there is standardization of result

Front 89

Solid Phase technology advantage

Back 89

can use hemolyzed, lipemic or icteric sample

Front 90

Means to separate or to remove

Back 90

apheresis

Front 91

2 methods of apheresis

Back 91

intermittent, and continuous

Front 92

Apheresis involving two puncture sites

Back 92

continuous

Front 93

Anticoagulant of choice for apheresis

Back 93

heparin

Front 94

Anticoagulant most commonly used in apheresis

Back 94

ACD

Front 95

Plasmapheresis donor should not have a protein below?

Back 95

6g/dL

Front 96

This is used to prevent hemosiderosis

Back 96

Plasmapheresis