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58 Cards in this Set

  • Front
  • Back

What does blood do?

1. transportation - oxygen, nutrients, waste


2. regulation - temperature, acid-base, fluid (electrolyte balance)


3. protection - against infection and bleeding

whole blood

3-5 times thicker than water

Blood PH

7.35 - 7.45

plasma

-mostly water


-clear yellowish liquid

formed elements

RBC - erythrocytes


WBC - leukocytes


platelets - thrombocytes

where are blood cells made?

stem cell - parent of all blood cells

3 cell making processes

erythropoiesis


leukopoiesis


thrombopoiesis

-poiesis

makes

where does cell developing occur?

bone marrow

bone marrow depression

occurs if bone marrow cannot produce enough blood cells


-aka myelosuppression

myelosuppression results:

1. aplastic anemia


2. leukopenia


3. thrombocytopenia


4. pancytopenia

aplastic anemia

RBC defiecency

Leukopenia

WBC deficiency

Thrombocytopenia

platelet deficiency

pancytopenia

depression of all blood

polycythemia

too many RBC

RBC:


1. function


2. aka


3. immature


4. #


5. Conatins

1. carry oxygen


2. erythrocytes


3. retics


4. 4.5-6.0 million


5. contains: hemoglobin

heme

carries iron

globin

shames RBC


protein

hematocrit

- measures RBC and checks for anemia


- fluid effects amount


- increased fluid = less hct


- decreased fluid = more hct

hct

hematocrit

oxyhemoglobin

- oxygen binds loosely with iron


- makes blood bright red

lack of oxygen

makes blood bluish red

sign of hypoxemia

cyanosis

Negative feedback

enough is a enough


reached homeostasis

RBC production:


Low oxygen...

-sends signal to kidney


-kidney signals bone marrow to make more RBC


-RBC # increase


-oxygen level increases

hemolysis

bursting of RBC

RBC hemolysis

-RBC is broken down into hemoglobin


-hemoglobin broken down into heme & globin


-recycled

Hemolytic Jaundice

-rapid breakdown of RBCs


-hyperbillirubinemia (too much billirubin)


-yellow stained tissue

WBC


1. #


2. aka


3. function

1. 5,000-10,000 microliter


2. leukocytes


3. protect the body against infection and inflammation

What can WBC do that RBC's can't?

leave the blood vessels to be able to go to site of infection or inflammation

sign of infection

increased WBC

how does WBC's get rid of infection?

destroy and removed bacteria

leukopenia

deficency in WBC

leukocytosis

increase amount with infection

leukemia

uncontrolled leukocyte production (too many)

Neutrophils


&


role

-most common granulocyte


-phagocytosis


-1st one on scene of injury- quickly move to the site of infection, where they phagocytose and remove tissue debris

WBCs:


Naughty Little Monkeys Eat Bananas says GRANpa BEN

1. neutrophils


2. lymphocytes


3. monocytes


4. eosinophils


5. basophils


6. GRANulocytes


7. Basophils


8. eosinophils


9. neutrophils

Plateltes


1. #


2. Function


3. aka

1. 150,000 - 450,000


2. prevent blood loss


3. thrombocytes

thrombocytopenia

decrease platelets - causing excess bleeding

Blood Counts: CBC

- provides information about blood composition


- shows percentage of the different types of WBCs

Blood Counts: Differential counts

shows percentage of each WBC type

Hemostasis:


Function


&


Steps

- prevention of blood loss


1. Spasm


2. Platelet plug


3. Clot

Formation of a Blood Clot

- injury produces prothrombin activator (PTA)


- PTA activates prothrombin to form thrombin


- thrombin activates fibrinogen to form fibrin fibers (clot)

Things needed to make blood clot

PTA, Calcium, prothrombin, thrombin, fibrinogen

anticoagulants

prevent coagulation

4 types of blood

A, B, AB, O

Universal recipident

AB

Universal Donor

O

Antigen-Antibody Interaction

blood clumps in response to interactions between antigens and antibodies

agglutination

blood clumps

prevent agglutination?

donor and recipient blood typed and cross-matched

Rh+

people with Rh factor

Rh-

those without Rh factor

Why is being Rh- bad?

- after first exposure to Rh factor, body creates antibody


- Rh- mother baby is Rh+


- first child is ok


- second child (due to first child exposing mother) mother's blood attacks baby's Rh+ blood

true universal donor

O-

true univeral recipient

AB+

erythroblastosis fetalis

mother is Rh- and baby is Rh+ and mother's blood attacks baby