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6 Cards in this Set
- Front
- Back
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Albumin |
Smallest plasma protein, accounts for 50-60% of plasma proteins. Produced by the liver. Provide osmotic pressure |
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Globulins |
Three types: alpha, beta, and gamma. Alpha and beta are produced by the liver and transport lipids and fat-soluble vitamins. Gamma are antibodies produced by lymphoid tissues, part of the immune system |
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Fibrinogen |
6% of plasma proteins. A clotting factor produced by the liver |
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Erythrocytes |
Flattened biconcave cells 7 microns in diameter and 2.2 microns thick. Explanation given in class for this shape is that it increases surface area for oxygen diffusion, but more convincing arguments exist that this shape increases the rotational inertia, decreasing spin and preventing turbulence in blood. Full of hemoglobin molecules that carry oxygen. Contain no nucleus or mitochondria, allowing the collapsed shape. Only have a lifespan of 120 days, after which they are removed by phagocytic cells in the spleen. |
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Intrinsic Pathway |
Slower activation of clotting by exposure of blood to negatively charged surfaces such as collagen. A chain of protease activations causes parathrombin to be converted into thrombin, which converts fibrinogen to fibrin monomers. |
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Extrinsic Pathway |
Faster activation of clotting caused by tissue factor, which is found in blood vessel walls and surrounding tissues. Has a shorter pathway of protease activations before forming thrombin. |
