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29 Cards in this Set

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What are the different types of hormones?

1-amino acid derivatives 2-peptides 3-Amino acid derivatives

Peptide hormones

-composed are made up of amino acids


they could be short or long.


-they are charged, must bind to a receptor on cell memb.


- it is considered a primary messenger.



what are some common second messengers?

1- Cyclin Adenosine monophosphate. (cAMP).




2-inositol triphosphate. (IP3).





give an example of how might a peptide hormone (first messenger work).

1- first messenger/hormone binds to receptor


2- receptor activates/deactivates adenylate cyclase.


3- adenylate cyclase lowers or higher cAMP (second messenger).


4- cAMP binds to protein kinase.


5-Protein kinase phosphorylates CREB. ( cyclinc response element binding).

Do peptide hormones need carriers in the blood stream?

No they don't because they are water soluble

Do steroid hormones need carriers in the blood stream?

Yes they do, because they are not water soluble.


They must be carried by proteins in the bloodstream

What is the mechanism of function for the steroid hormones?

1- they are nonpolar so they diffuse through the membrane to bind to their intracellular receptors.


2- they bind to the intracellular receptors go through conformational change and bind to DNA


3-they can increase or decrease transcription factors of gene.

amino acid-derivative hormones

like epinephrine and norepinepherine, triiodothryronine, and thyroxine.




notice the ending with "ine"

Direct hormones vs. Tropic hormones

direct: secreted then directly act on a target tissue.




Tropic: require and intermediary to act. They stimulate the production of another hormone by another endocrine gland.

Adrenal cortex is a gland that produces hormones. what kind of hormones does it produce?

steroid hormones

what are the endocrine glands?

1-pancreas


2- gondas (testes and ovaries).


3-pineal gland


4-pituitary gland


5-thyroid gland


6-hypothalamus.


7-PARATHYROID glands


8-Adrenal glands

Hypothalamus (gland)

-Located in the forebrain.


-produces tropic hormones to regulate the pituitary gland (paracrine, aka local hormones that affect the pituitary).



What role does the hypothalamus play in body functions

1- superachiasmatic nucleus recevies some of the light input from retina and controls sleep.


2-Blood osmolarity, appetite and satiety.


3-emotional experience and aggression.


what kind of regulation does the hypothalamus have?

negative feedback.

How does the thalamus communicate with the anterior pituitary?

by producing its tropic hormones in the hypopheseal portal system.

what are the hormones produced in the pheseal portal system by the hypothalamus? and what do they do?

they go to the anterior pituitary.




1-Gonadotropin-releasing hormone(GnRH)-> Leutinizing hormone(LH) and Follicile stimulating hormone.(FSH).


2- Thyroid releasing hormone---> Thyroid hormone


3-Growth-releasing hormone--> growth hormone.


4- Corticotropin-releasing hormone hormone--> adrenocortitropic hormone


5-prolactin-inhibition factor (PIF) inhibits the production of prolactin.

HOW do Hypothalamus-posterior pituitary communicate?




And what are the post. Pituitary hormones produced?

BY Neurons NOT hormones released by the hypothalamus. They go to the post.Pituitary and release two diff hormones.




1-oxytocin=stimulates uteris contractions and milk production.


2-Anti-diuretic hormone (vasopressin).= Reabsorbs water in the ducts of kidneys.

what are the hormones produced by the anterior pituitary?

1- follicle stimulating Hormone


2-Leutinzing hormone


3-Adrenocortitropic hormone


4-Thyroid


5-Prolactin


6-Endorphin


7-Growth hormone.

FLAT PEG

in milk production and ejection, what are the two pathways followed to produce milk?

1- Hypothalamus causes oxytocin to be produced from the posterior pituitary.


2- Hypothalamus stops the (PIF) or dopamine that inhibits the production of prolactin in the anterior pituitary.

where is growth hormone produced?


what does it do? and How?

1- produced by anterior pituitary


2- Prevents uptake of glucose by tissue.


3- this prevention makes glucose more available for muscles and bone to use up for growth.

where is Antidiuretic hormone produced and what does it do?

it is produced in the posterior pituitary. It reabsorbs water from the filtirate in the nephron and increases the kidney ducts' permeability to water.

CAUSES HIGH BLOOD PRESSURE.

what kind of feedback does oxytocin have and why is it produced

it has a positive feedback, the more contractions the more it is produced. During lactation and uterus contractions

1-what hormone controls the thyroid and


2-what hormones are produced by the thyroid.

thyroid stimulating hormone( ant. pit) controls it.


-triiodothyronine and thyroxine.


-Calcitonin

WHAT ARE THE FUNCTIONS OF THE THYROID

1- setting the base for metabolic rate


2- Calcium homeostasis.

what functions do triiodothyronine and thyroxine preform

SETTING THE BASE OF METABOLIC RATE.

Where is calcitonin produced and what does it do?

produced in thyroid and calcium homeostasis.

T3 and T4 have a feedback on TSH and TRH, what is it

NEGATIVE FEEDBACK.

Parathyroid glands: location. And hormones

posterior to thyroid. They produce Parathyroid hormone, which has an opposite effect of calcium.

what are the effects of parathyroid production

increasing the calcium levels in the body.




RESPORTION from the bones (release). increased absorption by the gut. Decrease excretion by the kidnesy