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42 Cards in this Set
- Front
- Back
Cellular membranes are fluid mosaics of _________ and _________. |
Cellular membranes are fluid mosaics of lipids and proteins. |
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The ______ of a phospholipid is polar but the _______ is nonpolar, making it a(n) __________ molecule. |
The head of a phospholipid is polar but the tail is nonpolar, making it an amphipathic molecule. |
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In the fluid mosaic model, the membrane is a mosaic of _________ molecules bobbing in a fluid bilayer of _______________. |
In the fluid mosaic model, the membrane is a mosaic of protein molecules bobbing in a fluid bilayer of phospholipids. |
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At relatively (high/low) temperatures, cholesterol molecules in plasma membranes restrict phospholipid movement, increasing the rigidity of the membrane. |
At relatively high temperatures, cholesterol molecules in plasma membranes restrict phospholipid movement, increasing the reigidity of the membrane. |
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A membrane remains fluid to a lower temperature if it is rich in phospholipids with (saturated/unsaturated) hydrocarbon tails. |
A membrane remains fluid to a lower temperature is it is rich in phospholipids with unsaturated hydrocarbon tails. |
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Cholesterol (raises/lowers) the temperature required for a membrane to solidify. |
Cholesterol lowers the temperature requires for a membrane to solidify. |
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Integral Proteins |
proteins which penetrate the hydrophobic interior of the lipid bilayer |
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Peripheral Proteins |
proteins loosely bound to surface of lipid bilayer, often to exposed parts of integral proteins |
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List six functions of membrane proteins. |
1. Transport 2. Enzymatic activity 3. Signal Transduction 4. Cell-Cell Recognition 5. Intercellular Joining 6. Attachment to cytoskeleton and ECM |
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___________ are carbohydrates that bond to lipids while __________ are carbohydrates that bond to proteins. |
Glycolipids are carbohydrates that bond to lipids while glycoproteins are carbohydrates that bond to proteins. |
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(Polar/Nonpolar) molecules are (hydrophilic/hydrophobic) and therefore can easily cross the bilayer without the help of membrane proteins. |
Nonpolar molecules are hydrophobic and therefore can easily cross the bilayer without the help of membrane proteins. |
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__________ transport is diffusion of a substance across a membrane with no energy investment. |
Passive transport is diffusion of a substance across a membrane with no energy investment. |
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Channel proteins have a (hydrophobic/hydrophilic) channel through which certain molecules or ions can travel to get into the cell. One example is the transport of water molecules through ____________. |
Channel proteins have a hydrophilic channel through which certain molecules or ions can travel to get into the cell. One example is the transport of water molecules through aquaporins. |
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____________ proteins hold onto molecules and change shape in order to transport them through the membrane. |
Carrier proteins hold onto molecules and change shape in order to transport them through the membrane. |
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Concentration Gradient |
the region along which the density of a chemical substance changes |
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Any substance will diffuse (down/up) its concentration gradient. |
Any substance will diffuse down its concentration gradient. |
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Osmosis |
the diffusion of free water across a selectively permeable membrane |
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Tonicity |
the ability of a surrounding solution to cause a cell to gain or lose water |
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In a (hypertonic/hypotonic) solution, a cell will lose water to its surroundings and become ________ if an animal cell or _________ if a plant cell. |
In a hypertonic solution, a cell will lose water to the surrounding solution and become shriveled if an animal cell or plasmolyzed if a plant cell. |
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In a (hypertonic/hypotonic) solution, a cell will gain water from its surroundings and become ______ if an animal cell or __________ if a plant cell. |
In a hypotonic solution, a cell will gain water from its surroundings and become lysed if an animal cell or turgid if a plant cell. |
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Osmoregulation |
the control of solute concentrations and water balance |
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In an isotonic solution, plant cells become __________. |
In an isotonic solution, plant cells become flaccid. |
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Plasmolysis |
the process by which plant cells shrivel and die when placed in hypertonic solutions; plasma membrane pulls away from the cell wall in multiple places |
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Facilitated Diffusion |
process by which transport proteins help certain molecules/ions that cannot passively diffuse through a membrane to cross the bilayer (throuhg channel or carrier proteins) |
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Channel proteins that transport ions are called _____ ____________. |
Channel proteins that transport ions are called ion channels. |
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______ channels open or close in response to a stimulus in order to facilitate passage through a membrane. |
Gated channels open or close in response to a stimulus in order to facilitate passage throuhg a membrane. |
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_______ transport uses energy to move solutes against their gradients. |
Active transport uses energy to move solutes against their gradients. |
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Sodium-Potassium Pump |
an active transport protein that moves two K+ ions into the cell and removes 3 NA+ ions out of the cell to maintain intercellular concentrations |
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The voltage across a membrane, which ranges from about ____ to ____ mV, is called the ________ __________. |
The voltage across a membrane, which ranges from about -50 to -200 mV, is called the membrane potential. |
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Because the inside of a cell is negative compared to the outside, the membrane potential favors the passive transport of (cations/anions) into the cell and of (anions/cations) out of the cell. |
Because the inside of a cell is negative compared to the outside, the membrane potential favors the passive transport of cations into the cell and of anions out of the cell. |
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Two forces drive the diffusion of ions across a membrane: _________ forces from the ion's concentration gradient and _________ forces from the membrane potential. Combined, they are called the __________ ____________. |
Two forces drive the diffusion of ions across a membrane: chemical forces from the ion's concentration gradient and electrical forces from the membrane potential. Combined, they are called the electrochemical gradient. |
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A transport protein that generates voltage across a membrane is called an _______ _________. |
A transport protein that generates voltage across a membrane is called an electrongenic pump. |
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The main electrogenic pump of plants, fungi, and bacteria is a(n) ________ ________. |
The main electrogenic pump of plants, fungi, and bacteria is a proton pump. |
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A ______________ protein can couple the "downhill" diffusion of a solute to the "uphill" transport of a second substance against its own concentration gradient. |
A cotransporter protein can couple the "downhill" diffusion of a solute to the "uphill" transport of a second substance against its own concentration gradient. |
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Bulk transport across the plasma membrane occurs by __________ and _________. |
Bulk transport across the plasma membrane occurs by exocytosis and endocytosis. |
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Exocytosis |
the process by which a cell excretes certain molecules (in bulk) by the fusion of vesicles with the plasma membrane |
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Endocytosis |
the process by which a cell takes in molecules and particulate matter by forming new vesicles from the plasma membrane |
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The three types of endocytosis are ____________, _______________, and __________. |
The three types of endocytosis are phagocytosis, pinocytosis, and receptor-mediated endocytosis. |
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Ligand |
any molecule that binds specifically to a receptor site on another molecule; examples include LDLs |
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Phagocytosis |
the process in which a cell engulfs a particle by extending pseudopodia around it and packaging it within a membranous sac called a food vacuole; the particle will be digested after the food vacuole fuses with a lysosome "cellular eating" |
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Pinocytosis |
the process in which a cell continually "gulps" droplets of extracellular fluid into tiny vesicles, formed by infoldings of the plasma membrane lined on the cytoplasmic side by coat proteins ("coated vesicle") "cellular drinking" |
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Receptor-mediated Endocytosis |
specialized type of pinocytosis that enables the cell to acquire bulk quantities of specific substances by grouping receptor proteins for those solutes on coated pits and then forming coated vesicles |