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42 Cards in this Set

  • Front
  • Back

Cellular membranes are fluid mosaics of _________ and _________.

Cellular membranes are fluid mosaics of lipids and proteins.

The ______ of a phospholipid is polar but the _______ is nonpolar, making it a(n) __________ molecule.

The head of a phospholipid is polar but the tail is nonpolar, making it an amphipathic molecule.

In the fluid mosaic model, the membrane is a mosaic of _________ molecules bobbing in a fluid bilayer of _______________.

In the fluid mosaic model, the membrane is a mosaic of protein molecules bobbing in a fluid bilayer of phospholipids.

At relatively (high/low) temperatures, cholesterol molecules in plasma membranes restrict phospholipid movement, increasing the rigidity of the membrane.

At relatively high temperatures, cholesterol molecules in plasma membranes restrict phospholipid movement, increasing the reigidity of the membrane.

A membrane remains fluid to a lower temperature if it is rich in phospholipids with (saturated/unsaturated) hydrocarbon tails.

A membrane remains fluid to a lower temperature is it is rich in phospholipids with unsaturated hydrocarbon tails.

Cholesterol (raises/lowers) the temperature required for a membrane to solidify.

Cholesterol lowers the temperature requires for a membrane to solidify.

Integral Proteins

proteins which penetrate the hydrophobic interior of the lipid bilayer

Peripheral Proteins

proteins loosely bound to surface of lipid bilayer, often to exposed parts of integral proteins

List six functions of membrane proteins.

1. Transport


2. Enzymatic activity


3. Signal Transduction


4. Cell-Cell Recognition


5. Intercellular Joining


6. Attachment to cytoskeleton and ECM

___________ are carbohydrates that bond to lipids while __________ are carbohydrates that bond to proteins.

Glycolipids are carbohydrates that bond to lipids while glycoproteins are carbohydrates that bond to proteins.

(Polar/Nonpolar) molecules are (hydrophilic/hydrophobic) and therefore can easily cross the bilayer without the help of membrane proteins.

Nonpolar molecules are hydrophobic and therefore can easily cross the bilayer without the help of membrane proteins.

__________ transport is diffusion of a substance across a membrane with no energy investment.

Passive transport is diffusion of a substance across a membrane with no energy investment.

Channel proteins have a (hydrophobic/hydrophilic) channel through which certain molecules or ions can travel to get into the cell. One example is the transport of water molecules through ____________.

Channel proteins have a hydrophilic channel through which certain molecules or ions can travel to get into the cell. One example is the transport of water molecules through aquaporins.

____________ proteins hold onto molecules and change shape in order to transport them through the membrane.

Carrier proteins hold onto molecules and change shape in order to transport them through the membrane.

Concentration Gradient

the region along which the density of a chemical substance changes

Any substance will diffuse (down/up) its concentration gradient.

Any substance will diffuse down its concentration gradient.

Osmosis

the diffusion of free water across a selectively permeable membrane

Tonicity

the ability of a surrounding solution to cause a cell to gain or lose water

In a (hypertonic/hypotonic) solution, a cell will lose water to its surroundings and become ________ if an animal cell or _________ if a plant cell.

In a hypertonic solution, a cell will lose water to the surrounding solution and become shriveled if an animal cell or plasmolyzed if a plant cell.

In a (hypertonic/hypotonic) solution, a cell will gain water from its surroundings and become ______ if an animal cell or __________ if a plant cell.

In a hypotonic solution, a cell will gain water from its surroundings and become lysed if an animal cell or turgid if a plant cell.

Osmoregulation

the control of solute concentrations and water balance

In an isotonic solution, plant cells become __________.

In an isotonic solution, plant cells become flaccid.

Plasmolysis

the process by which plant cells shrivel and die when placed in hypertonic solutions; plasma membrane pulls away from the cell wall in multiple places

Facilitated Diffusion

process by which transport proteins help certain molecules/ions that cannot passively diffuse through a membrane to cross the bilayer (throuhg channel or carrier proteins)

Channel proteins that transport ions are called _____ ____________.

Channel proteins that transport ions are called ion channels.

______ channels open or close in response to a stimulus in order to facilitate passage through a membrane.

Gated channels open or close in response to a stimulus in order to facilitate passage throuhg a membrane.

_______ transport uses energy to move solutes against their gradients.

Active transport uses energy to move solutes against their gradients.

Sodium-Potassium Pump

an active transport protein that moves two K+ ions into the cell and removes 3 NA+ ions out of the cell to maintain intercellular concentrations

The voltage across a membrane, which ranges from about ____ to ____ mV, is called the ________ __________.

The voltage across a membrane, which ranges from about -50 to -200 mV, is called the membrane potential.

Because the inside of a cell is negative compared to the outside, the membrane potential favors the passive transport of (cations/anions) into the cell and of (anions/cations) out of the cell.

Because the inside of a cell is negative compared to the outside, the membrane potential favors the passive transport of cations into the cell and of anions out of the cell.

Two forces drive the diffusion of ions across a membrane: _________ forces from the ion's concentration gradient and _________ forces from the membrane potential. Combined, they are called the __________ ____________.

Two forces drive the diffusion of ions across a membrane: chemical forces from the ion's concentration gradient and electrical forces from the membrane potential. Combined, they are called the electrochemical gradient.

A transport protein that generates voltage across a membrane is called an _______ _________.

A transport protein that generates voltage across a membrane is called an electrongenic pump.

The main electrogenic pump of plants, fungi, and bacteria is a(n) ________ ________.

The main electrogenic pump of plants, fungi, and bacteria is a proton pump.

A ______________ protein can couple the "downhill" diffusion of a solute to the "uphill" transport of a second substance against its own concentration gradient.

A cotransporter protein can couple the "downhill" diffusion of a solute to the "uphill" transport of a second substance against its own concentration gradient.

Bulk transport across the plasma membrane occurs by __________ and _________.

Bulk transport across the plasma membrane occurs by exocytosis and endocytosis.

Exocytosis

the process by which a cell excretes certain molecules (in bulk) by the fusion of vesicles with the plasma membrane

Endocytosis

the process by which a cell takes in molecules and particulate matter by forming new vesicles from the plasma membrane

The three types of endocytosis are ____________, _______________, and __________.

The three types of endocytosis are phagocytosis, pinocytosis, and receptor-mediated endocytosis.

Ligand

any molecule that binds specifically to a receptor site on another molecule; examples include LDLs

Phagocytosis

the process in which a cell engulfs a particle by extending pseudopodia around it and packaging it within a membranous sac called a food vacuole; the particle will be digested after the food vacuole fuses with a lysosome




"cellular eating"

Pinocytosis

the process in which a cell continually "gulps" droplets of extracellular fluid into tiny vesicles, formed by infoldings of the plasma membrane lined on the cytoplasmic side by coat proteins ("coated vesicle")




"cellular drinking"

Receptor-mediated Endocytosis

specialized type of pinocytosis that enables the cell to acquire bulk quantities of specific substances by grouping receptor proteins for those solutes on coated pits and then forming coated vesicles