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34 Cards in this Set

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Events of Prophase

chromatin --> chromosomes




centrioles separate --> spindle pole formation (MTs)




nuclear membrane degraded

Events of Metaphase

Spindles are on opposite ends of cell




metaphase ends when chromosomes are on equatorial plate

Events of anaphase

centromeres split = sister chromatids separate




(MTs shorten)

Events of telophase

spindle poles disappear




nuclear membrane reforms




chromosomes --> chromatin




cytokinesis

When does recombination occur in meiosis?

Prophase I




crossing over happens at the chiasma

When does disjunction occur in meiosis?

segregation




Anaphase I = 2n --> n

What are the functional components of the testes?

1. seminiferous tubules = produce sperm




2. interstitial cells of Leydig = secrete androgens including testosterone

What nourishes sperm cells once they are produced?

Sperm are produced in the seminiferous tubules




Sperm are nourished in Sertoli cells

Where is seminal fluid produced and what is its purpose?

1. seminal vesicles = fructose for nourishment, alkalinity




2. prostate = alkalinity




3. bulbourethral glands = clear stuff to lubricate urethra

Pathway of sperm through male reproductive system

Seve(n) Up




Seminiferous tubules


Epedidymis


Vas deferens


Ejaculatory duct




Urethra


Penis

Steps in Spermatogenesis

Spermatogonia (2n)


Development


Primary spermatocytes (2n)


Meiosis I


Secondary spermatocytes (n)


Meiosis II


Spermatids (n)


Maturation


Spermatozoa (n)



What component of sperm allows it to enter the ovum?

Acrosome = covers head and derived from golgi

How is the ability to reproduce controled?

1. Puberty = hypothalamus releases GnRH




2. GnRH = stimualtes anterior pituitary to produce LH and FSH




3. FSH + LH = sex hormone activation and develops reproductive system

Hormone role in male sexual development

FSH = stimulates Sertoli cells to trigger sperm maturation




LH = stimulates interstitial cells to produce (more) testosterone and androgens




T = secondary male sex characteristics

What are the effects of androgen insensitivity syndrome?

AIS




XY male has absend or deffective androgen receptors




genetic male has female secondary sex characterisitcs

Role of hormones in female sexual development

FSH = promote estrogen secretion




LH = stimulate corpus luteum to secrete progesterone




E = Establishes endometrium




P = Protects endometrium

Follicular phase

1. begins when menstral flow sheds old endometrium


2. GnRH secreted by hypothalamus. increases because [E] and [P] are low


3. GnRH = increase LH and increase FSH (FSH>LH)


4. E slowly rises and regrows endometrium stimulating vascularization


5. ends with ovulation

Ovulation

E levels increase to threshold causing positive feedback



LH surge --> follicle rupture --> egg release into uterus




LH surge = primary oocyte to complete meiosis I

Luteal Phase

Ovulation = ruptured follicle becomes corpus luteum




corpus luteum = P produced




P = negative feedback. decrease GnRH,LH, FSH

Menstration

no implantation = corpus luteum atrophies into albicans




no corpus luteum = no E or P




No E or P = high GnRH and endometrium sloughed off

How is pregnancy established?

1. Blastocyst secretes human chorionic gonadoatropin (hCG)




2. hCG = LH analog - maintains corpus luteum




3. Corpus luteum = P + E for maintaining uterine lining




4. 2nd trimester placenta takes over and hCG declines

From zygote to gastrula, what are the stages of development?

Zygote




2,4,8,16 embryo




morula




blastula




gastrula

During what stage of development does implantation occur?

Blastula stage

What is induction?

The process by which cells influence differentiation of adjacent cells




Allows organs/tissues to form

What is the fate of neural crest cells

Will develop into PNS cells




Sensory ganglia


Autonomic ganglia


Adrenal ganglia


Schwann cells

What organs originate from the ectoderm?

1. Integument = epidermis, hair, nails, epithelia of nose, mouth, and anal canala




2. Lens of eye


3. Nervous system


4. Adrenal medulla


5. inner ear

What organs originate from the mesoderm?

Muscoskeletal system


circualtory system


excretory system


gonads




Muscular + connective tissue of digestive + respiratory sysytem




Adrenal cortex

What organs originate from the endoderm?

epithelial linings of the digestive + respiratory tract




liver


pancreas


thyroid


bladder




digestive, urinary, and reproductive tracts

1. define determination




2. define differentiation

1. commitment of a cell to have a particular function (cell lineage) in the future




2. changing of structure and function of a cell to match cell type. Due to selective transcription

Describe methods of determination

1. during cleavage, existing mRNA or protein is systemically packaged into daughter cells




2. morphogens can be secreted by neighboring cells

Types of cell-cell communication

autocrine = same cell




paracrine = nearby cells




juxtacrine = through direct contact




endocrine = through bloodstream

Role of veins + arteries in umbilical cord

2 veins = oxygenated blood mother --> fetus




1 artery = deoxygenated blood fetus -->mother

Name the shunts that reroute blood from lungs of a baby

1. foramen ovale = RA --> LA




2. ductus arterious = extra blood from PA --> Aorta

Name the shunts that reroute blood away from liver in fetus/baby

ductus venosus = umbilical vein --> vena cava