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25 Cards in this Set

  • Front
  • Back

During contraction, the parallel thick and thin filaments of the myofibrils are connected by __________ that span the space between the parallel thick and thin filaments.

crossbridges

Caveolae are important because they contain

voltage-regulated Ca2+ channels which allow Ca2+ entry into the muscle cell.

A contraction that generates force and moves a load is known as __________,

isotonic

Whereas one that generates force without movement is known as __________.

isometric

A motor unit consists of

one neuron and the muscle fibers it controls

After death, when metabolism stops, in which step of the contractile cycle will skeletal muscles remain stuck if they have been contracting, for most of the first day or so?

the rigor state

An important difference between single-unit and multiunit smooth muscle is

numerous gap junctions in single-unit smooth muscle, which allow many cells to work together as a sheet.

As ATP binds to the myosin head at the beginning of a muscle contraction cycle,

the myosin head detaches from actin.

At the conclusion of the power stroke,

inorganic phosphate has been released from the myosin.


actin has been moved toward the M line.


ADP is released from the myosin head.


the myosin head is tightly bound to actin.

Compared to skeletal muscle, smooth muscle in a latch state

is slower to contract in response to a stimulus and sustains contractions longer without fatigue

For striated muscle, each myosin head (leaflet) has

a binding site for an ATP molecule, a binding site for an actin molecule, and the ability to swivel (rachet) when powered by ATP

Excitation-contraction coupling refers to

the chemical and electrical events form the neuron inwards that trigger the contractile events in a muscle fiber.

In smooth muscle, what is the small protein chain that regulates contraction and relaxation?

myosin light chain kinase (MLCK)

Complete the following sentence to describe the state of relaxed muscle fibers: myosin heads are

not bound to actin, and contain ADP and Pi.

One of the major differences among skeletal muscle fiber types is in their resistance to fatigue. The fibers with the most endurance rely on __________ for energy.

oxidative phosphorylation

Regulation of cross-bridge formation in striated muscle is accomplished by

tropomyosin, troponin, and calcium ions

Smooth muscle cells lack which protein(s)?

troponin

Striated muscles are so-called because of a repeating pattern of light and dark bands. One repeating unit of the banding pattern is called a

sarcomere

The H zone contains

thick filaments

The I band contains

thin filaments

For both striated and smooth muscle the contraction cycle is triggered by the rise in __________ in intracellular fluid.

Ca2+

The period of time during which the sarcomeres return to their resting length is referred to as

the relaxation phase

When the membrane potential of a cell is resting which of the following ions are at equilibrium?

Cl-

The resting membrane potential of cells appears to have resulted as a solution to what problem?

The need to have the same quantity of solute on either side of the membrane.

A pharmacomechanical coupling in smooth muscle results in no change in the membrane potential.

true