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11 Cards in this Set
- Front
- Back
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is cholesterol in structural component esterified or not? When stored is chol E or not?
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unesterified free is structural
stored as CE |
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the majority of cholesterol is synthesized from _______ via ______.
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acetylcoa via hmgcoa
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where is the primary synthesis of cholesterol
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liver
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what catalyzes the bommitted step in cholesterol biosynthesis
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HMGCOA red
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what is the major metabolic product of cholesterol
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biole acids
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what is the major route of cholesterol excretion from the body
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bile components that are not reabsorbed in the small intestine
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As TG are removed fro the hydrophobic core of chylomicrons and VLDL via the action of _____ _____
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lipoprotein lipase
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what enzyme turns cholesterol transferred to HDL and esterified
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LCAT which locks in the cholesterol
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what are the three functions of HDL
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sufrace lipid acceptor TG to VLDL
promote exchange of essential apoproteins reverse cholesterol transport |
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what activates SREBP? what inhibits it?
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chol = inhibition
insulin activates SREBP |
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what happens to plasma cholesterol if you increase saturated fats
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increase it!
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