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18 Cards in this Set
- Front
- Back
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how do you get TG out of the liver?
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VLDL
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What is the equation for de novo synthesis of FA
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8AcetylCoa + 14NADPH + 7ATP + water-->
palmitic + 8HSCOA |
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where does de novo FA synthesis happen?
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in the cytoplasm of the liver
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how do you get acetylcoa out of the mitochondria and into the cytoplasm
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citrate shuttle
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how much ATP does the citrate shuttle cost
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2 ATP
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what catalyzes acetycoa to citrate?
citrate to acetyl Coa? |
citrate synthase
ATP citrate lyase |
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where do you get the NADPH from in the citrate shuttle
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malate to pyruvate
NADP+ dep malate DH |
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how do you get from pyruvate to OAA
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pyruvate carboxylase
use 1 aTP |
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how do you get from acetylcoa to malonylCoa
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acetylcoa carboxylase
biotin ATP |
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what does the fatty acid synthase look like
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1 acetylCOA + 7 malonylCoA + 14 NADPH + H2o --> palmitic acid + 7CO2 + 8HSCOA + 7H2O
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describe the mechanism of fatty acid synthase
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synthase and acacenzyme sites
two reductions NADPH in both and FADH2 in second ketoneketone --> alcohol ketone --> ene --> ane |
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how do you make TG from fatty acids?
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DHAP to glycerol 3P
OR glycerol to glycerol3P L phosphatidic acid all fatty As TG |
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what will process you VLDL TG
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lipoprotein lipase
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what enzyme does adpiose lack to deal with glycerol
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glycerol kinase
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what is the key site of regulation for fatty acid biosynthesis
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acetycoa carboxlase
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does insulin promote TG storage or break down in adipose?
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storage
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does insulin promote TG storage or break down in adipose?
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storage
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does insulin promote TG storage or break down in adipose?
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storage
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