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11 Cards in this Set
- Front
- Back
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What does orlistat do?
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Inhibits pancreatic and gastric lipase, results in 30% blockage of dietary fats.
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Which lipoprotein particle has the highest concentration of cholesterol and its esters?
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LDL
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VLDL appear particularly when?
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After a carby meal.
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What is the composition of HDL?
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Unesterified cholesterol, phospholipid, apoA, apoE, apoC.
Initially disc shaped but as they fill up w/cholesterol they are spherical. |
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What is PCAT?
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phosphatidylcholine:cholesterol acyltransferase.
This converts cholesterol to esterified cholesterol in the HDL particle to trap it in there. |
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What does ApoA do for HDL?
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Activates PCAT. (phosphatidyl:cholesterol acyltransferase protein)
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What is the purpose of hormone sensitive lipase?
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Mobilization of stored fat.
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How many ATPs are yielded from each cycle of Fatty acyl metabolism?
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14 ATP
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What happens in Zellwegger Syndrome?
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Accumulation of very long FA's due to a malformed peroxisome.
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What happens in adrenoleukodystrophy?
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Accumulation of very long fatty acid chains because they cannot be transported into the peroxisomes.
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What causes Acetyl CoA go towards to formation of ketone bodies?
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Lack of oxaloacetate in the TCA cycle. Therefore shunted towards ketone body synthesis.
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