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18 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Glycolysis
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Phosphofructokinase-1
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cytoplasm
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Gluconeogenesis
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Fructose-1,6-bisphosphatase
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cytoplasm/mitochondria
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TCA cycle
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Isocitrate dehydrogenase
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mitochondria
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Glycogen synthesis
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Glycogen synthase
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Glycogenolysis
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Glycogen phosphorylase
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cytoplasm
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HMP shunt
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Glucose-6-phosphate dehydrogenase
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cytoplasm
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De novo pyrimidine synthesis
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Carbamoyl phosphate synthetase II
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De novo purine synthesis
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Glutamine-PRPP amidotransferase
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Urea cycle
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Caramoyl phosphate synthetase I
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mitochondria/cytoplasm
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Fatty acid synthesis
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Acetyl-CoA carboxylase
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cytoplasm
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Fatty acid oxidation
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Carnitine acyltransferase I
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mitochondria
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Ketogenesis
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HMG-CoA synthase
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Cholesterol synthesis
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HMG-CoA reductase
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Hexokinase
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High affinity low Km
Low capacity Vmax Ubiquitous uninduced by insulin |
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Glucokinase
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Liver and B cells of pancreas
Low affinity high Km high capacity high Vmax induced by insulin |
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TCA cycle
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Citrate synthase
Isocitrate dehydrogenase ( isocitrate to a-KG) a-KG dehydrogenase (a-KG to succinyl CoA) |
a-KG dehydrogenase and PYRUVATE DEHYDROGENASE require:
Pyrophostate (B1) FAD (B2 riboflavin) NAD (B3 niacin) CoA (B5, pantothenate) Lipoic acid |
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Gluconeogenesis irreversible enzymes
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Pyruvate carboxylase - mitochondria (pyruvate to oxaloacetate)
PEP carboxykinase - cytosol (oxaloacetate to PEP) Fructose-1,6-bisphosphatase - cytosol (Fructose-1,6-bp to fructose-6-P) Glucose-6-phosphatase |
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Myeloperoxidase
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Generates hydrochloric acid
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