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13 Cards in this Set

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What is the rate limiting enzyme for:

Glycolysis?
Phosphofructokinase-1 (PFK-1)

Fructose-6-phosphate + ATP --> Fructose-1,6-bisphosphate + ADP
What is the rate limiting enzyme for:

Gluconeogenesis?
Fructose-1,6-bisphosphatase

Fructose-1,6-bisphosphate --> Fructose-6-phosphate
What is the rate limiting enzyme for:

TCA Cycle?
Isocitrate dehydrogenase (CITRIC acid cycle --> isoCITRATE)

Isocitrate (6C) --> alpha-ketoglutarate (5C) + CO2 + NADH
What is the rate limiting enzyme for:

Glycogen Synthesis?
Glycogen synthase
What is the rate limiting enzyme for:

Glycogenolysis?
Glycogen phosphorylase
What is the rate limiting enzyme for:

HMP shunt?
Glucose-6-phosphate dehydrogenase (G6PD)
What is the rate limiting enzyme for:

De novo pyrimidine synthesis?
Carbamoyl phosphate synthetase II
(aka Aspartate transcarbamoylase, ATCase)
What is the rate limiting enzyme for:

De novo purine synthesis?
Glutamine-PRPP amidotransferase
What is the rate limiting enzyme for:

Urea cycle?
Carbamoyl phosphate synthetase I
What is the rate limiting enzyme for:

Fatty acid synthesis?
Acetyl-CoA carboxylase (ACC)
What is the rate limiting enzyme for:

Fatty acid oxidation?
Carnitine acyltransferase I
What is the rate limiting enzyme for:

Ketogenesis?
HMG-CoA synthase
What is the rate limiting enzyme for:

Cholesterol synthesis?
HMG-CoA reductase