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15 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Most abundant protein in the body |
Collagen |
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Most common form of collagen |
Type I |
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Collagen is rich in? |
Glycine Proline |
GP |
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Types of Collagen |
Type I -bONE, skin, tendon II - cartwolage III - Re3culin IV- BM "floor type 4" VII: beneath stratified squamous epithelium |
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Ehlers Danlos |
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3 Types of Ehlers Danlos |
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AD abnormal collagen type I |
Osteogenesis Imperfecta |
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Osteogenesis Imperfecta Manifestations |
Brittle Bones Blue Sclerae Dental Imprefections Hearing loss -conductive bc of the ossicles |
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Defect in Type IV collagen - the major collagen found in BM of glomeruli |
Alport Syndrome (AlFOURTH) |
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Alport Syndrome Manifestations |
Sensorineural hearing loss Ocular lesions Hematuria (main presenting sign) May develop into ESRD |
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Alport syndrome |
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DX? |
Epidermolysis Bullosa -defect in Collagen 7: anchors basal lamina to.collagen fibrils -Minor trauma: skin breaks and blisters |
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Vitamin C deficiency |
Scurvy vit C def - decreased cross linking of collagen fibers |
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Scurvy Manifestations |
Spongy Gums Poor wound healing Loose teeth Petechiae on skin and mucous membrane common in sailors |
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Dx? |
Scurvy |
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