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10 Cards in this Set
- Front
- Back
What is the normal concentration of albumin in the serum?
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4g/dL
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Name 4 F(x)'s of Albumin?
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translocate bilirubin, fatty acids, and other compounds bound non-specifically. Also penicillin, aspiring, sulfa-drugs, and steroid hormones
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Where is albumin synthesized?
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Liver`
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What class of plasma proteins is not synthesized in the liver?
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Gamma Globulins
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What is the most abundant plasma protein?
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Albumin
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Which PP binds iron?
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Alpha-2 globulins and beta globulin fraction involved in iron homeostasis
TRANSFERRIN |
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Which PP binds vitamin A derivatives?
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Alpha-1 globulin which contains retinol binding protein
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What happens to the free hemoglobin the serum?
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Fe2+, ferous iron, is usually lost through the kidneys, unless haptoglobulin binds to it.
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Name a blue protein and it's Fx
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Ceruloplasmin: copper-containing protein w/ Cu ions in 1+ and 2+ states used to oxidize any free Fe2+ to Fe3+ in the serum
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what is the most abundant alpha-1 globulin? fx? clinical result of it's absence or malfunction?
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Alpha-1 antiprotease (AKA antitrypsin) 90%.
inhibits elastase, an enzyme that breaks down connective tissue elastin PTs homozygeous for defect in elastin are at high risk for emphysema. |