Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
5 Cards in this Set
- Front
- Back
|
ADA deficiency
|
Mechanism: genetic lack of working adenosine deaminase for purine salvage.
SCID: no T/B cell growth Frequent infections, v/b/f + resp. prob. Drugs for infection, bovine ADA + IgG injections, bone marrow transp., gene therapy |
|
|
Beriberi
|
Malnourished - low thiamin. TPP falls. Transketolase activity stops.
Neurological and muscular impairment. Paralysis and/or congestive heart failure. Vitamin replenishment |
|
|
Cancer/methotrexate
|
Meth. inhibits dihydrofolate reductase. THF not regenerated, nucleotide synthesis stops.
Effective against rapidly dividing cancer cells. |
|
|
Fabry's disease
|
Lack of alpha-galactosidase
Adolescent onset. Burning pain. Heart attacks, kidney disease, strokes with age. |
|
|
Familial Hypercholesterolemia
|
Genetic lack of working LDL receptor. Autosomal dominant.
Elevated LDL, atherosclerosis, early heart disease, tendon xanthomas. Diet/excercise, statins, sequestrans, plasmapharesis, liver transplant. |
