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26 Cards in this Set
- Front
- Back
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Where does Glycolysis occur?
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All cells (but for different reasons)
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When does glycolysis occur?
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Depends on the location
1) Liver 2) Brain 3) Skeletal Muscle |
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When does glycolysis occur in the Liver?
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-in a well-fed state
-to maintain safe and stable blood sugar level |
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When not in a well-fed state, what does the Liver use as its principle fuel?
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Fatty acids (released in lipolysis)
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How does the liver get the fatty acid to use for fuel when not in the well-fed state?
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ALBUMIN binds & transports fatty acids released from adipocytes in lipolysis
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What is the main fatty acid used by the liver?
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Palmitic Acid
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What is the structure of Palmitic Acid?
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C-16 Saturated Fatty Acid
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Palmitic Acid is integral to what?
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Myelin
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How often does glycolysis run in the brain?
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Always
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What does the brain use for energy?
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1) products of glycolysis
2) ketones |
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During exercise, what do your muscles use for energy?
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Glycogen
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Describe what happens with glycolysis in muscle during a well fed state?
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Glycolysis is INHIBITED
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Other than in the brain, how often does glycolysis run?
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22 out of 24 hours
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What happens with glycolysis in the well fed state of skeletal muscle?
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Glycolysis is INHIBITED
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Why is glycolysis inhibited in the well fed state of skeletal muscle?
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To form glycogen
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_____________ is highly active in maximal power output (maximum contraction) of skeletal muscle.
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Glycolysis
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In skeletal muscle, where is calcium released from?
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Sarcoplasm
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In a skeletal muscle contraction, what does calcium bind to?
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Calmodulin
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What turns OFF glycogenesis?
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Glycogen synthase
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What turns ON glycogenesis?
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Glycogen phosphorylase
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When insulin is in the well-fed state, there is net dephosphorylation of which 2 enzymes?
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1) glycogen synthase
2) glycogen phosphorylase |
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When insulin is in the well fed state, glycogen synthase is __________.
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ACTIVE
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When insulin is in the well fed state, glycogen phosphorylase is _______________.
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INHIBITED
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When there is high blood glucose what will activate glycogen phosphorylase?
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Calcium
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When there is high blood glucose, what will activate glycogen synthate?
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ATP
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In hyperglycemia, what is inhibited in this state?
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PFK-1
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