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91 Cards in this Set

  • Front
  • Back
Gene
A single trait such as tongue rolling, tongue folding, freckles etc...
Polygenic trait
brought about by several genes. Ex: hair color, eye color, height...
Independent Assortment
Giving traits an equal opportunity of occuring together
Allele
Variation or form of a gene.
Ex:
R = Tongue Rolling Allele,
r = non tongue rolling Allele
Genotype
An individuals allele combination.
EX.
RR Rr rr
Phenotype
An individuals physical expression of its genotype.
EX.
RR Rr rr
roller roller non roller <--- phenotype
Homozygous Dominant
RR - Has both dominant gene allele's
Heterozygous
Rr - Has both dominant and recessive allele, but dominant masks the recessive allele.

Homozygous recessive
rr - Both allele's are recessive.
Father of Genetics
Gregor Mendel
Allele Key
Allele Key
___________

R = Rolling
r = Non Rolling
Genotypic Ratio
1RR:2Rr:1rr <-----
3 Rollers : 1 Non Rollerr
Phenotypic Ratio
1RR:2Rr:1rr
3 Rollers : 1 Non Roller <-----
How many Gametes can be made with genotype RrTt?
RT, Rt, rT, rt
Incomplete Dominance
-One allele does not completely mask the other allele
-Blending in offspring
-Cannot use upper and lowercase letters
EX. Flowers -
R1= Red Flower Allele
R2= White Flower Allele
Offspring is Pink
Sex Linkage (x-linkage)
Genes found on X chromosomes of Father but not the Y.
EX.
XHXh vs. XHY
Sex Linkage trait examples?
Hemophila, color blindness, fragile x etc...
Blood Type Genotypes?
IAIA, IAi = Blood type A
IBIB, IBi = Blood type B
ii = Blood type O
IAIB = Blood type AB

IA and IB are dominant over ii
Which blood type is universal?
Blood Type O because it has no glycoprotein
Non-sexed linked Autosomal Recessive human genetic disorder examples...
Tay Sacks, Sickle Cell disease
Autosomal Dominant Genentic Disorder
Huntingtons Disease
Why is a disease caused by a recessive allele more common?
Because the allele is hidden in carriers
Nondisjunction
Failure of chromosomes to separate properly during Meiosis
DNA
-Has genetic information
-Composed of deoxyribose nucleotides (sugar)

What are the DNA bases?
Adenine
Guanine
Cytosine
Thymine

AGCT
What are the DNA complimentary base pairs?
A - T
G - C
DNA bases (strands) are held together by...
Hydrogen Bonds
Backbone of DNA is composed of...
Sugar/Phosephate groups
_________________
/S\ /S\
P/ \P/ \P.....
__________________
DNA Replication
Occurs in nucleus during S phase of Interphase
DNA Replication STEPS
1. DNA strands seperate
2. Both strands act as a pattern
3. Need free deoxyribose nucleotides
4. Need an enzyme, DNA plymerase
5. DNA will bring in and hook together the complimentary bases
6. Result: The double helix!
Where does DNA store its information?
Its in sequence of nucleotides
Mutations
Change in the nucleotide sequence in DNA.
In some cases, there is no effect because the
genetic code is redundant -- several codons code for the same amino acids
RNA
-Decodes the DNA and is composed of Ribose Nucleotides
-Found in nucleus and cytoplasm
-Ribose-Sugar
-Single stranded
-Bases AGC and U (Uracil)
-There is no T (Thymine) in RNA
Central Dogma of DNA function
DNA ---> RNA ------> Protein
Transcription
-Uses DNA as a template to form RNA
-Occurs in DNA during Interphase
Transcription Process
1. DNA strands seperate
2. Only 1 strand acts as a template called a "Template Strand" or "Sense Strand"
3. Need Ribose Nucleotides
4. Need enzyme, RNA polymerase
5. Bring polymerase and hook together complimentary bases.
6. Goes to cytoplasm, DNA unchanged
Result: RNA strand, released.
Ribosomal RNA
rRNA - combines with certain proteins to form Ribosomes
Transfer RNA
tRNA - acts as a carrier of amino acids; Each
specific for specific amino acids
Messenger RNA
mRNA - Has the information for making a
specific protein. Sequence of nucleotides
determined by the DNA
Central Dogma for mRNA
Transcription Translation
| |
DNA ------------> mRNA ---------------> Protein
| | |
Sequence SoN Sequence
of Nucleotides | of Amino Acids
V
Need tRNA with
Amino Acids
Genetic Code
Given in terms of mRNA and every 3 nucleotides in the RNA is called a codon and codes for Amino Acids.
Anticodon
3 special nucleotides that will base pair with the appropriate codon of mRNA and bring the correct amino acid
Causes of Mutation
Radiation (Xrays), UV light, chemicals,
spontaneous (chance)
Types of Mutations -
Point Mutation - base substitution, change in one nucleotide pair in the DNA. EX> UV light
Frameshift Mutation - Addition or deletion of a nucleotide pair. Reading of mRNA has shifted. Bigger effect.

What is PCR?
(DNA Technology)
Polymerase chain reaction - Can be used to make copies of a gene

What can be done using Restriction Enzymes and Recombinant DNA?
Used to cut bacteria is specific locations; sticky ends.

Recombinant DNA
Taking DNA from one source and placing it in another source.
USED FOR -
Crop modification, making new vaccines, insulin created this way, gene therapy
DNA Hybridization
Used for deciding how closely related organisms are to each other
Theory of Evolution
All existing organisms have arisen from
pre-existing organisms through a change in the ancestors genetic make up (change in allele
frequencies)
Micro Evolution
change in the genetic make up of a population over time. Population (group of interbreeding organisms in an area)
Natural Selection
Some organisms in a population reproduce and others do not due to environment factors
Environmental Factors
Temperature, food, nesting sites, natural disasters, elevation, predators, loss of habitat, pollution, water availability
Directional Selection
Selection for one phenotype and selection for the other phenotype extreme
Stabilizing Selection
Selection against both phenotype extremes and selection for the intermediate phenotype
Disruptive Selection
Selection against intermediate phenotype and selection for both phenotype extremes
Evolution Founders
Charles Darwin and Alfred Wallace
Evidence of Evolution?
-Earth has changed over time
-Variations in populations
-Organisms are well adapted to their environments
-Fossil Records
-Comparative anatomy
-DNA studies
Genetic Drift
(Evolution without Natural Selection)
Change in the genetic makeup of a small population due to chance events
Gene Flow
(Evolution without Natural Selection)
Migration to or from 1 population to another. Can lead to a change in allele frequencies.

EX. country mouse to city mouse population

What is a Species?

Group of interbreeding organisms reproductively isolated from organisms. (NOT BACTERIA!)


If they mate and they produce fertile offspring they are the same species.

Geographical Isolation

Stops gene flow.


Ex = Continental drift, oceans, rivers, island, mountain range, wall/freeway.

Permanent Reproductive Isolation Mechanism

Genetically based.

Behavior/Appearances Isolation Mechanism

Bird call/Song


Frog calls

Season Isolation

Mate at different times of the year.

Chemical Isolation

Pharomones

Mechanical Isolation

Part dont fit

Gamete Incompatibility

Gametes will not fuse

Habitat Isolation

Live and get food in different habitats

Hybrid Weakness

2 different species mate but the offspring are too weak to reproduce.

Hybrid Infertility

Two species mate but the offspring are sterile. Male Donkey and Female horse = mule (non fertile)

Transition of plants from water to land

1/2 billion years ago, land plants arose from ancestrial green alge

Plant Adaptations

Cuticle, Development of Vascular tissue, Dev of true roots, pollon does not depend on water for sperm to swim, evolution of seeds

Vascular Tissue

Xylem and Phloem. Allows to get bigger.

Seeds

Can stay dormant until good conditions

Water Transport

Plants get longer at their tips

Cohesion Tension Theory of water Transport

Cohesion, Tension, Adhesion

Cohesion

Water sticks together due to hydrogen bonds

Tension

Negative pressure (like a vacuum)

Adhesion

Water sticks to other molecules (like blood)

Transportation of Water

Loss of water as vapor from leaves

Capillary Action

Attraction of water to sides of the tube and the rest of the water follows due to cohesion.

Ancient Bacteria

Often live in extreme enviroments

True Bacteria

Everywhere, hetetrophic or autotrphic.


(Phototrophic)

Eukaryotes

Portists, Fungi, plants and animals

Protists

Eukarotic, can be hetertrophic or Phototrophic,

Plant- like Protist

Algae

Animal- like protists

Protozoans (heto)

Fungi-like protists

Slime mold (heto)

Fungi

Eukaryotic, multicellular mostly.


ex. Mushrooms, molds, mildews


Heto, absorb nutrients not ingest

Plants

Eukaryotic, phototrophic, multicellular,


ex. mosses, ferns, conifers, flowering plants

Animals

Eukaryotic, multicellular, heterotrophic, ingests food.




ex. worms, mammals, birds