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31 Cards in this Set
- Front
- Back
anabolism
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building molecules
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catabolism
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breaking down molecules
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metabolic reations
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often organized into pathways (don't go directly from starting molecule to product)
need enzyme for each reaction in the process |
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energy
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the capacity to do work
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potential energy
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energy stored in a system due to its location or spacial arrangement
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free energy
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G
energy that is available to do work more energy in complexity than randomness |
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first law of thermodynamics
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energy cannot be created or destroyed but converted from one form to another
*heat energy not available to do work "lost to the environment" |
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second law of thermodynamics
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every energy transfer or transformation increases entropy
more random, more entropy, less potential energy organisms use energy from the sun to build complex structures |
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exergonic
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reactants have more free energy than products
spontaneous -G |
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endergonic
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reactants have less free energy than products
require input of energy to complete +G energy can be harnessed by coupling |
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open systems
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constant input
do not reach equilibrium |
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enzymes
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protein catalysts that lower activation energy requirements
-ase=enzyme not used up or affected during reaction substrate specific some require cofactors to function inhibitors can prevent from functioning (competitive, noncompetitive) |
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ATP
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cell energy currency
harvest it from the food we eat ADP + Pi (add third phosphate) |
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allosteric enzymes
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alternate between active and inactive forms
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negative feedback loops
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somewhere near the beginning of the pathway, an enzyme is inhibited
if the end product is accumulating, pathway might be turned off |
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respiration
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glucose + o2 --> co2 + h2o + ATP
exergonic glycolysis, citric acid cycle, oxidative phosphorylation releases 30-32 ATP |
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glycolysis
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first step of respiration
takes place in cytosol splits glucose into 2 pyruvic acids (pyruvate) +2 net ATP, 2 NADH (most energy) ATP formed through substrate-level phosphorylation controlled through feedback inhibition of phosphofructokinase |
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acetyl coA formation
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pyruvate moves to mitochondrial matrix, loses co2 in the process and remaining 2 carbons (acetate) attach to a coenzyme A to become acetyl coA
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citric acid/krebs/TCA cycle
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4 C molecule + 2 C (from coA) --> 6 C citrate
goes in circle to reform 4 C molecule products at this point: 4 ATP, 10 NADH, 2 FADH2 |
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oxidative phosphorylation
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electrons and H+ from NADH and FADH2 transfer to o2 from water
energy released in steps electrons drop in energy as they go down electron transport chain towards o2 energy released along chain used to pump H+ ions across innermitochondrial membrane and through chemiosmosis--ATP synthase as they move through channel |
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anaerobic respiration (fermentation)
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without o2, oxygen transport shuts down
in cytosol converts NADH to NAD+ yields only 2 ATP/glucose molecule only glycolysis happens w/o o2 |
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NAD+ needed by
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glycolysis
citric acid cycle pyruvate -> acetyl coA (not electron transport or chemiosmosis) |
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autotrophs
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produce their own food
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heterotrophs
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eat other things
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photosynthesis
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happens in chloroplasts
6co2 + 6h2o --> glucose + 6o2 light reactions & calvin cycle violet & red light most useful |
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light reactions
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photosystem II --> photosystem I
II produces NADPH provide ATP and NADH to the calvin cycle |
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calvin cycle
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5 carbon RuBO + C = 6 C molecule
falls apart into 2 G3P must do 6x |
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stages of cell signaling
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reception
transduction response |
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reception
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ligand can be any size & solubility
membrane bound receptors-water soluble ligands ligands that are small and hydrophobic diffuse through membrane to bind to receptors inside cell |
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transduction
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signal transduction pathway (amplifies response)
second messengers & enzyme cascades protein kinases stick phosphate to proteins from ATP |
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response
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not all cells that bind the same ligand respond the same way
apoptosis: programmed cell death |