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31 Cards in this Set

  • Front
  • Back
anabolism
building molecules
catabolism
breaking down molecules
metabolic reations
often organized into pathways (don't go directly from starting molecule to product)
need enzyme for each reaction in the process
energy
the capacity to do work
potential energy
energy stored in a system due to its location or spacial arrangement
free energy
G
energy that is available to do work
more energy in complexity than randomness
first law of thermodynamics
energy cannot be created or destroyed but converted from one form to another
*heat energy not available to do work "lost to the environment"
second law of thermodynamics
every energy transfer or transformation increases entropy
more random, more entropy, less potential energy
organisms use energy from the sun to build complex structures
exergonic
reactants have more free energy than products
spontaneous
-G
endergonic
reactants have less free energy than products
require input of energy to complete
+G
energy can be harnessed by coupling
open systems
constant input
do not reach equilibrium
enzymes
protein catalysts that lower activation energy requirements
-ase=enzyme
not used up or affected during reaction
substrate specific
some require cofactors to function
inhibitors can prevent from functioning (competitive, noncompetitive)
ATP
cell energy currency
harvest it from the food we eat
ADP + Pi (add third phosphate)
allosteric enzymes
alternate between active and inactive forms
negative feedback loops
somewhere near the beginning of the pathway, an enzyme is inhibited
if the end product is accumulating, pathway might be turned off
respiration
glucose + o2 --> co2 + h2o + ATP
exergonic
glycolysis, citric acid cycle, oxidative phosphorylation
releases 30-32 ATP
glycolysis
first step of respiration
takes place in cytosol
splits glucose into 2 pyruvic acids (pyruvate)
+2 net ATP, 2 NADH (most energy)
ATP formed through substrate-level phosphorylation
controlled through feedback inhibition of phosphofructokinase
acetyl coA formation
pyruvate moves to mitochondrial matrix, loses co2 in the process and remaining 2 carbons (acetate) attach to a coenzyme A to become acetyl coA
citric acid/krebs/TCA cycle
4 C molecule + 2 C (from coA) --> 6 C citrate
goes in circle to reform 4 C molecule
products at this point: 4 ATP, 10 NADH, 2 FADH2
oxidative phosphorylation
electrons and H+ from NADH and FADH2 transfer to o2 from water
energy released in steps
electrons drop in energy as they go down electron transport chain towards o2
energy released along chain used to pump H+ ions across innermitochondrial membrane and through chemiosmosis--ATP synthase as they move through channel
anaerobic respiration (fermentation)
without o2, oxygen transport shuts down
in cytosol
converts NADH to NAD+
yields only 2 ATP/glucose molecule
only glycolysis happens w/o o2
NAD+ needed by
glycolysis
citric acid cycle
pyruvate -> acetyl coA
(not electron transport or chemiosmosis)
autotrophs
produce their own food
heterotrophs
eat other things
photosynthesis
happens in chloroplasts
6co2 + 6h2o --> glucose + 6o2
light reactions & calvin cycle
violet & red light most useful
light reactions
photosystem II --> photosystem I
II produces NADPH
provide ATP and NADH to the calvin cycle
calvin cycle
5 carbon RuBO + C = 6 C molecule
falls apart into 2 G3P
must do 6x
stages of cell signaling
reception
transduction
response
reception
ligand can be any size & solubility
membrane bound receptors-water soluble ligands
ligands that are small and hydrophobic diffuse through membrane to bind to receptors inside cell
transduction
signal transduction pathway (amplifies response)
second messengers & enzyme cascades
protein kinases stick phosphate to proteins from ATP
response
not all cells that bind the same ligand respond the same way
apoptosis: programmed cell death