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23 Cards in this Set
- Front
- Back
What are the parts and functions of the urinary system?
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Kidneys (2) – bean-shaped, fist-sized organ where urine is formed
Ureters (2) – small, muscular tubes that carry urine from the kidneys to the bladder Bladder (1) – expandable organ that stores urine until it is expelled from the body Urethra (1) – tube (longer in men than women) that carries urine from the bladder to the outside of the body |
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Functions of urinary system
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1.Excretion of metabolic wastes
2.Maintenance of water-salt balance 3.Maintenance of acid-base balance 4.Hormone secretion: renin and erythropoietin |
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Excretion
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Mostly of nitrogenous wastes:
Urea made by the breakdown of amino acids in the liver Uric acid made by the breakdown of nucleotides Creatinine made by muscle cells from the breakdown of creatine phosphate |
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Maintenance of water-salt and acid-base balance
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Both are homeostatic mechanisms
Water-salt balance helps to maintain blood pressure The kidneys by excreting hydrogen ions and reabsorbing the bicarbonate ions this acid-base balance helps maintain a blood pH of ~7.4 |
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Kidney structure
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Renal cortex – an outer granulated layer
Renal medulla – cone-shaped tissue masses called renal pyramids Renal pelvis – central cavity that is continuous with the ureter |
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nephrons
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Microscopic functional unit of the kidney that produces urine
> 1 million per kidney |
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Glomerulus
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a knot of capillaries inside the glomerular capsule where pores produce a blood filtrate
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Proximal convoluted tubule
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epithelial layer with a brush border of microvilli to allow reabsorption of filtrate components
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loop of nephron
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U-shaped structure that has a descending limb to allow water to leave and an ascending limb that pushes out salt
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distal convoluted tubule
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made of epithelial cells rich in mitochondria and thus is important for movement of
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Collecting ducts
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several nephrons share a collecting duct which serve to carry urine to the renal pelvis
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What are the 3 processes in the formation of urine?
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Glomerular filtration
Tubular reabsorption Tubular secretion |
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Glomerular filtration
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Water and small molecules move from the glomerulus to the glomerular capsule while large molecules and formed elements remain in the glomerular blood
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Tubular reabsorption and secretion
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Many molecules and ions are reabsorbed from the nephron into the blood
A second way to remove substances such as drugs, H+ and creatinine from the blood |
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Reabsorption of salt
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increases blood volume
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Atrial natriuretic hormone (ANH)
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secreted by the heart when blood volume increases and inhibits the secretion of aldosterone which promotes the excretion of Na+
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Establishment of solute gradient
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a greater concentration is towards the inner medulla
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Reabsorption of water
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due to the solute gradient water leaves the descending limb of the loop of the nephron then antidiuretic hormone (ADH) from the pituitary plays a role in water reabsorption at the collecting duct
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What role does alcohol play in this process?
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Alcohol inhibits ADH secretion and thus increases the amount of urine and dehydration
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How is the acid-base balance maintained?
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Buffers are a chemical or a combination of chemicals that can take up excess H+ or excess OH-
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Kidney function disorders
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Diabetes, hypertension and inherited conditions are the most common cause of renal disease and failure such as:
Urethritis – localized infection of the urethra Cystitis – infection in the bladder Pyelonephritis – infection of the kidneys Kidney stones – hard granules formed in the renal pelvis due to UTI’s, enlarged prostate, pH imbalances or intake of too much calcium Uremia – high levels of urea and other waste substances in the blood that causes a serious condition when water and salts are retained due to extensive nephron damage |
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how can Kidney failure be treated?
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Hemodialysis – uses an artificial kidney machine to subtract and add substances to the blood as needed
Continuous ambulatory peritoneal dialysis (CAPD) – used the peritoneal membrane to filter the blood and allows a person to go about their normal life without interruption Kidney replacement – single kidney transplant with a high success rate _____________________________________ |
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How do the kidneys maintain homeostasis?
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Excrete wastes
Urea, creatinine and uric acid Water-salt balance of blood Helps regulate blood volume and pressure Acid-base balance of blood Helps regulate pH Assistance to other systems Endocrine, cardiovascular, skeletal, muscular, nervous and digestive |