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38 Cards in this Set
- Front
- Back
purines
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large membranes, adenine and guanine
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pyrimidine
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smaler, cytosine thymine and uracil
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dna
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provides for own replication, directs rna synthesis, and through rna controls proten synthesis
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rna
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controls protein synthesis, nucleic acid, mRNA= messanger, interacts with cell's protein-synthesizing machinery to direct production of polypeptide
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somatic cells
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46 chromosomes (all other cells)
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gametes
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reproductive cells, 23 chrom
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mitosis
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produce somatic cells, division of nucleus followed by cytokeneisis
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meiosis
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produce gametes (daughter cells) in ovaries or testies
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S-phase
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replicate DNA
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pleiotropy
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ability of gene to affect on organism in many ways
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epistasis
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gene alters phenotype exxpression from 1st locus to 2nd
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polygenic inheritance
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quantitative variation, an addictive effect of 2 or more genes on single phenotype charactr
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cystic fibrosis
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mucus buildup, hard to breath, children die before 5, recessive disease have to be homozygous recessive to be carrier
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sickel cell
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oxygen content decreases in red blood cells to hcange its form
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aneuploidy
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abnormal number of chrom (1-2 diff--> 45 instead of 46)
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hemophelia
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sexlinked recessive trait, absense of 1 or more protiens required for blood clotting, prolonged bleeding
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muscular dystrophy
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sexlinked, males, barely live past 20. weakening of muscles and loss of coordination
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Hershey and Chase
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DNA is genetic material of phage (t2) which infect EColi. nucleic acides, not proteins, are hereditary material, for at least viruses
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Chargaff
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adenine=thymine guanine=cytosine
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Watson and Crick
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DNA is helical shape with 2 strands (double helix) found which enzymes paired together (a-t, c-g)
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Roasalind Frankin
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x-ray diffraction photo of DNA that helped waston and crick
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Meselson and Stahl
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semiconservative model (parent molecule emerges from replication process intact)
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DNA polymerase
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elongation of new DNA replicatoin fork is catalyzed by enzyme (mechanisM)
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priming in replication
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primase
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elongation in replication
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dna polymerase
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replacement of RNA primer by dna in replication
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dna polymerase
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synthesis of lagging strand starts by priming for okazaki fragment in replication
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primase
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elongation of fragment in replication
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dna polymerase
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relication of RNA primer by DNA and joining of fragments
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dna polymerase and ligase
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differences in meiosis and mitosis
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theres 2 divisions in meiosis, chromosomes line up differently
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autosomal
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not sex chromosome (44 autosomes, 2 sex chrom)
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polyploidy
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extra SET of chromosomes (instead of 46, you have teiploid-69, or tetraploid-92)
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letters and sugar of DNA
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A,G,C,T and deoxyribose
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letters and sugar of RNA
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A,G,C,U and ribose
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semiconservative
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each new molecule has one origional strand to determine template of new strand
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transcription
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dna-> rna
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translation
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rna-> polypeptide
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mutation
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change in gene
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