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38 Cards in this Set

  • Front
  • Back
purines
large membranes, adenine and guanine
pyrimidine
smaler, cytosine thymine and uracil
dna
provides for own replication, directs rna synthesis, and through rna controls proten synthesis
rna
controls protein synthesis, nucleic acid, mRNA= messanger, interacts with cell's protein-synthesizing machinery to direct production of polypeptide
somatic cells
46 chromosomes (all other cells)
gametes
reproductive cells, 23 chrom
mitosis
produce somatic cells, division of nucleus followed by cytokeneisis
meiosis
produce gametes (daughter cells) in ovaries or testies
S-phase
replicate DNA
pleiotropy
ability of gene to affect on organism in many ways
epistasis
gene alters phenotype exxpression from 1st locus to 2nd
polygenic inheritance
quantitative variation, an addictive effect of 2 or more genes on single phenotype charactr
cystic fibrosis
mucus buildup, hard to breath, children die before 5, recessive disease have to be homozygous recessive to be carrier
sickel cell
oxygen content decreases in red blood cells to hcange its form
aneuploidy
abnormal number of chrom (1-2 diff--> 45 instead of 46)
hemophelia
sexlinked recessive trait, absense of 1 or more protiens required for blood clotting, prolonged bleeding
muscular dystrophy
sexlinked, males, barely live past 20. weakening of muscles and loss of coordination
Hershey and Chase
DNA is genetic material of phage (t2) which infect EColi. nucleic acides, not proteins, are hereditary material, for at least viruses
Chargaff
adenine=thymine guanine=cytosine
Watson and Crick
DNA is helical shape with 2 strands (double helix) found which enzymes paired together (a-t, c-g)
Roasalind Frankin
x-ray diffraction photo of DNA that helped waston and crick
Meselson and Stahl
semiconservative model (parent molecule emerges from replication process intact)
DNA polymerase
elongation of new DNA replicatoin fork is catalyzed by enzyme (mechanisM)
priming in replication
primase
elongation in replication
dna polymerase
replacement of RNA primer by dna in replication
dna polymerase
synthesis of lagging strand starts by priming for okazaki fragment in replication
primase
elongation of fragment in replication
dna polymerase
relication of RNA primer by DNA and joining of fragments
dna polymerase and ligase
differences in meiosis and mitosis
theres 2 divisions in meiosis, chromosomes line up differently
autosomal
not sex chromosome (44 autosomes, 2 sex chrom)
polyploidy
extra SET of chromosomes (instead of 46, you have teiploid-69, or tetraploid-92)
letters and sugar of DNA
A,G,C,T and deoxyribose
letters and sugar of RNA
A,G,C,U and ribose
semiconservative
each new molecule has one origional strand to determine template of new strand
transcription
dna-> rna
translation
rna-> polypeptide
mutation
change in gene