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75 Cards in this Set

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Undernourished

- Diet is deficient in calories


- Glycogen in liver and muscles -> fat from adipose tissues [where excess calories stored] -> breakdown of own proteins


- -> Atrophy, consumption of brain proteins

Essential nutrients

- Chemicals an animal requires but cannot synthesize


- AA, FA, vitamins, minerals











Four aspects

Malnourished

- Unbalanced diet, including excessive eating

Essential amino acids

- human adults can only produce 12/20 amino acids needed to make proteins


- kwashiorkor: unbalanced diet -> deficiency, humans cannot store excess AA

Essnetial fatty acids

- unsaturated, e.g. linoleic acid -> phospholipids for membranes


- most diets include sufficient quantities

Vitamins

- req'd in much smaller quantities (0.01 to 100 mg/day)


- may serve catalytic function in coenzymes


- water-soluble: excess in urine


- fat-soluble ADEK: excess stored as fat

Minerals

- inorganic, may serve maintenance roles (Ca2+) or as parts of enzymes/other molecules (Cu, Fe)

Herbivores

- eat autotrophic organisms


- have teeth with broad, ridged surfaces for grinding vegetation

Carnivores

- eat other animals


- have pointed canines and incisors used to crush, shred, and tear away flesh

Omnivores

- eat other animals and autotroph


- have relatively unspecialized dentition

Ingestion

- first stage of food processing


- act of eating

Digestion

- second stage of food processing


- cleaves macromolecules into component monomers (polysacch -> simple sugars, proteins -> amino acids, fats + glycerol -> fatty acids)

Enzymatic hydrolysis

- Hydrolytic enzymes catalyze digestion of macromolecules by adding water


- Occurs in specialized compartment, preventing damage of animals' own cells

Absorption

- third stage of food processing


- uptake of small molecules

Elimination

- fourth stage of food processing


- undigested material passes out of digestive compartment

Suspension-feeders

- Sift food particles from water


- E.g. clams, oysters (trap food on gills), baleen whales (strain food from water)

Substrate-feeders

- Live on or in food source and eat through


- E.g. leaf miners

Deposit-feeders

- Type of substrate-feeder that ingests partially decayed organic materials along with substrate


- E.g. earthworms

Fluid-feeders

- Suck nutrient-rich fluids from a living host


- E.g. leeches; aphids ingest phloem from trees

Bulk-feeders

- Eat relatively large pieces of food


- Most animals -> kill prey or tear off vegetation

Intracellular digestion

- Food vacuole: simplest digestive compartment


- When hydrolytic enzymes are secreted into food vacuole and digestion occurs


- Sponges: all digestion intracellular

Extracellular digestion

- Occurs in continuous compartments


- After some hydrolysis

Gastrovascular cavity

- Digestive sac with a singular opening


- Functions in both digestion and nutrient distribution


- Possessed by most animals with a simple body plan

Complete digestive tract

- Combination of extracellular and intracellular digestion that allows animals to feed on larger prey items


- Phagocytosis: for microscopic foods


- Possessed by animals more complex than cnidarians and platyhelminthes

Alimentary canal

- Digestive tube running in between two openings: mouth and anus


- Can be organized into specialized regions -> stepwise digestion and absorption for efficiency


- Unidirectional

Peristalsis

- Rhythmic smooth muscle contraction


- Pushes food along tract

Sphincters

- Modifications of the muscle layer into ringlike valves


- Occur at some junctions between compartments


- Regulate passage of materials through system

Salivary gland

- Accessory gland

Pancreas

- Accessory gland


- Compound gland: exocrine produces hydrolytic enzymes and bicarbonate buffer to neutralize acid chyme


- Endocrine produces and secretes hormones (insulin, glucagon)

Liver

- Accessory gland


- Produces bile

Gallblader

- Accessory gland


- Stores bile

Oral cavity

- Where physical and chemical digestion begin


- Chewing -> makes food easier to swallow, increases surface area for enzymes


- Saliva: (1) mucin, protects mouth from abrasion and lubricates food (2) buffers that neutralize acids, (3) antibacterial agents (4) salivary amylase

Salivary amylase

- Enzyme that hydrolyzes starch and glycogen -> maltose, small polysaccharides

Bolus

- Formed by tongue as it tastes and manipulates food


- Pushed back into oral cavity and pharynx

Pharynx

- intersection of digestive and respiratory system

Epiglottis

- Swallowing moves it to block entrance of trachea (glottis)


- Directs food through pharynx, to esophagus

Esophagus

- Muscular tube that conducts food from pharynx to stomach through peristalsis

Stomach

- Large, saclike structure just below diaphragm that stores food and performs preliminary digestion


- Has elastic wall with rugae: folds that can expand to accommodate up to 2L of food


- Storage capacity permits periodic feeding

Gastric juice

- Composed of HCl (secreted by parietal cells in stomach epithelium) and Pepsin


- HCl provides acidity, which kills bacteria, denatures protein, and starts conversion of pepsinogen to pepsin

Pepsin

- Splits peptide bonds next to some amino acids


- Endopeptidase: only splits peptide bonds located within polypeptide chain

Pepsinogen

- Secreted by chief cells in stonach epithelium


- A zymogen (inactive protease), precursor to pepsin

Acid chyme

- Nutrient broth


- Result of churning and enzyme action

Pyloric sphincter

- Regulates passive of acid chyme into small intestine


- Located at bottom of sromach


- Relaxes at intervals


- Permits small quantities of chyme to pass

Small intestine

- About 6m in length


- Site of most enzymatic hydrolysis of food and andorption of nutrients

Duodenum

- first 25 cm of small intestine


- Where carbohydrate (C) digestion begins again, pancreatic amylases hydrolyze starch and glycogen into disaccharides


- Each disaccharide has own disaccharidase


- Final breakdown of carbohydrates occurs where sugars will be absorbed

Bile

- Does not contain digestive enzymes


- Contains bile salts which emulsify fat


- Contains pigments that are byproducts of destroyed RBCs

Trypsin

- Endopeptidse that catalyzes conversion of more trypsinogen to trypsin


- Catalyzes conversion of other zymogens

Chymotrypsin

- Endopeptidase


- Digests large polysaccharides into shorter chains by breaking internal peptide bonds adjacent to certain amino acids


- Converted from chymotrypsinogen by trypsin

Carboxypeptidase

- Exopeptidase that splits amino acids, one at a time, off the end of a polypeptide with a free carboxyl group


- Production looped by trypsin

Amimopeptidase

- Protein-digesting enzyme secreted by lining of small intestine


- Begins at the end of a polypeptide that has a free amino group


- Splits off one amino acid at a time

Dipeptidase

- Protein-digesting enzyme secreted by lining of small intestine


- Splits small polypeptides

Enteropeptidase

- Converts trypsinogen to trypsin in small intestine protein digestion (C -> P -> NA -> F)


- Activates zymogens secreted by pancreas

Nucleases

- Hydrolyze DNA and RNA into nucleotides during nucleic acid digestion (N)


- Other hydrolytic enzymes (nucleotidases and nucleosidases) break nucleotides -> nucleosides, nitrogenous bases, sugars, phosphates

Emulsification

- Occurs during fat digestion (F), exclusive to small intestine


- Produces many small fat droplets that collectively have a large surface area exposed for digestion

Lipase

- Secreted by pancreas into duodenum


- During fat digestion (F), hydrolyzed gats into glucerol and fatty acids

Jejunum

- Specialized for nutrient absorption

Ileum

- Specialized for nutrient absorption

Villi

- Projections from large folds in the walls


- Increases surface area for absorption tk about 300m²

Microvilli

- Microscopic projections from villi

Brush border

- Microvillar surface


- Exposed to lumen of intestine

Lacteal

- Tiny lymph vessel


- Along with capillaries, penetrate hollow core of each villus

Chylomicrons

- Absorbed glycerol and fatty acids recombined in epithelial cells to form fats, that are coated with proteins


- Enter lacteals

Hepatic portal vessel

- Where capillaries and veins draining nutrients from villi converge


- Leads directly to liver


- Various organic molecules used, stored, or converted to different forms


- Blood flows at a rate of 1L/min

Gastrin

- Released from the stomach in response to presence of food


- Stimulates gastric juice (HCl and pepsin) release from stomach


- Stimulates mitosis and development of new mucosa cells

Secretin

- Released from duodenum in response to acid chyme entering from stomach


- Signals pancreas to release bicarbonate buffer to neutralize acid chyme

Cholecystokinin (CCK)

- Released from duodenum in response to acid chyme entering from stomach


- Signals gallbladder to release bile


- Signals pancreas to release pancreatic enzymes into duodenum


- May be involved with satiety reflex of brain

Enterogastrone

- Released from duodenum in response to presence of far in chyme


- Inhibits peristalsis in stomach


- Slows digestion

Large intestine

- Connects to small intestine at a T-shaped junction containing a sphincter

Colon

- Around 1.5 m long


- Inverted U


- Water reabsorption

Cecum

- Blind end of T in large intestine

Appendix

- Fingerlike extension of cecum composed of lymphoid tissue

Feces

- Wastes of digestive tract


- Moved through colon through peristalsis


- Intestinal bacteria live on organic material in feces, and some produce Vit. K absorbed by host


- May contain an abundance of salts

Rectum

- Stores feces


- Has involuntary sphincter

Ruminant

- Organism with elaborate alimentary canal structure


- Swallows food then brings it back up to keep chewing


- E.g. cow, sheep

Anus

- Has voluntary sphincter


- For feces elimination