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36 Cards in this Set
- Front
- Back
Selective permeability
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A property of biological membranes that allows some substances to cross more easily than others.
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Fluid mosaic model
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The currently accepted model of cell membrane structure, which envisions the membrane as a mosaic of individual protein molecules drifting laterally in a fluid bilayer of phospholipids.
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Peripheral proteins
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A protein appendage loosely bound to the surface of a membrane and not embedded in the lipid bilayer.
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Transport proteins
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A transmembrane protein that helps a certain substance or class of closely related substances to cross the membrane.
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Concentration gradient
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An increase or decrease in the density of a chemical substance in an area. Cells often maintain concentration gradients of ions across their membranes. When a gradient exists, the ions or other chemical substances involved tend to move from where they are more concentrated to where they are less concentrated.
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Osmosis
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The diffusion of water across a selectively permeable membrane from an area of low solute concentration to an area of high solute concentration
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Osmoregulation
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control of water balance when necessary for adaptation for life. ex paramecium has a contractile vacuole that acts as a pump
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Turgid
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Very firm. A walled cell become turgid if it has a greater solute concentration than its surroundings, resulting in entry of water.
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Plasmolysis
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plasmolysis
A phenomenon in walled cells in which the cytoplasm shrivels and the plasma membrane pulls away from the cell wall when the cell loses water to a hypertonic environment. |
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Facilitated diffusion
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The spontaneous passage of molecules and ions, bound to specific carrier proteins, across a biological membrane down their concentration gradients.
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Gated channels
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A protein channel in a cell membrane that opens or closes in response to a particular stimulus.
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Active transport
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The movement of a substance across a biological membrane against its concentration or electrochemical gradient with the help of energy input and specific transport proteins.
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Sodium-potassium pump
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an active transport protein in the plasma membrane of animal cells that transports sodium out of the cell and potassium into the cell against their concentration gradients.
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Membrane potential
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The charge of + and - ions between a cell’s cytoplasm and the extracellular fluid. Membrane potential affects the activity of excitable cells and the transmembrane movement of all charged substances.
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Electrochemical gradient
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The diffusion gradient of an ion, representing a type of potential energy that accounts for both the concentration difference of the ion across a membrane and its tendency to move relative to the membrane potential.
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Electrogenic pump
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An ion transport protein that generates voltage across a membrane.
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Proton pump
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main electrogenic pump of plants, fungi and bacteria; its a transport protein that generates a voltage across a membrane
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Cotransport
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The coupling of the downhilldiffusion of one substance to the uphilltransport of another against its own concentration gradient.
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HYPERTONIC
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high area of solute, low concentration of solvent; A is hypertonic to B; cell loses water and shrinks
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ISOTONIC
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mostly constant, equal solute to solvent; yet equilibrium is never truly reached
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HYPOTONIC
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low are of solute, high concentration of solvent; B is hypotonic to A; cell gains water and grows
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What are the staple ingredients of the plama membrane?
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- Lipids and proteins
- To a lesser extent, carbohydrates |
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What is the most abundant lipid in the plasma membrane?
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Phosopholipids
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What is AMPHIPATHIC?
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A phosopholipid is amphipatic in that it has both hydrophilic and hydrophobic regions.
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What is an INTEGRAL PROTEIN?
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A protein that pentrates th hydrophobic core of the lipid bilayer.
- Many can be transmembrane prtoein, which completely span the membane |
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EXOCYTOSIS vs ENDOCYTOSIS
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how large molecules exit and enter the cell; secretory cells use exo to export their products and cells take in macromolecules by forming vesicles in endo; uses opposing proteins; requires energy
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Types of endocytosis
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Pinocytosis (cellular drinking), phagocytosis (cellular eating) and receptor-mediated (use of protein)
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What is PASSIVE TRANSPORT?
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no ATP required, moves down concentration gradient from high to low; diffusion is a form if it
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Types of DIFFUSION?
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Simple - pass phospholipid through plasma membrane on own
Facilitated - need a transport protein. ex aquaporin - for water only |
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What is OSMOSIS?
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water diffusion only
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Fluidity of membranes
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phospholipids in the pm can move within the bilayer; most of the lipids, and proteins, drift laterally; rarely does a molecule flip flop, membrane must remain fluid to work properly
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6 major functions of membrane proteins
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transport, enxymatic actinity, signal transduction, cell-cell recognition, intercellular joining, attachment to the cytoskeleton and extracellular matrix
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cell to cell recognition
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by binding to surface molecules, often carbs, on pm. Membrane carbs bond to lipids and proteins forming glycolipids and glycoproteins
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permeability of lipid layer
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layer is hydrophobic (nonpolar) and only molecules that can dissolve can pass thru; polar (sugar) molecules cannot pass easily
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transport proteins
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(carrier proteins) allow passage of hydrophilic substances across membrane
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aquaporins
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channel proteins that facilitate the passage of water
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