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20 Cards in this Set
- Front
- Back
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What are some viruses that can cause oral blisters?
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Herpes Simplex Viruses (HHV1&2)
Herpers Caricella Zoster (HHV3) Coxsackie Viruses |
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What type of virus is Herpes Simples?
(DNA/RNA/mRNA/protein) |
DNA
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When and how do people get infected with herpes, and how many people who become infected get an oral lesion?
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Spread through saliva, usually early childhood.
Mostly infection is asymptomatic. In 1% there is an acute herpatic gingivo-stomatitis, with a fever, cervical lymphadenopathy, oral ulcers anywhere in the mouth |
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What does diagnosis involve and show?
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Exfoliative cytology or rarely biopsy, shows infected cells with multinucleation and ballooning degeneration.
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What is the tx of Primary Herpes?
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If identified in first 2-3 days, aciclovir may be helpful
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More on tx of herpes?
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Care is basically symptomatic. Analgesics, antipyretics, topical LA (so can eat/drink, avoid dehydration), ice blocks for peads. Care to not spread virus to other body sites or people
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What is the prognosis of herpes simplex?
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Good - usually only one episode that last 10-14 days without tx. 25% will have at least one episode of recurrent disease.
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Describe Recurrent Herpes Labialis
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Triggered by UV light or trauma, it effects the vermilion zone or perioral sink. Causes erythema, followed by cluster of vesicles. Vesicles rupture, form crust, heals in 7-10 days. Topical antiviral agens give a statistically significant decrease in healing time.
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Desribe Recurrent Intraoral Hepes?
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Relatively uncommon. Few symptoms - irritated or rough feeling. Cluster of shallow ulcers. Confined to mucosa bound to periosteum. Heals in one week.
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What is the tx for an immunosuppr4essed patient with herpes?
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IV acyclovir for acute cases with specialist consultation. Maintenance therapy with oral acyclovir may be necessary
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If a dentist doesn't wear gloves and touches a herpatic lesion, what do they get?
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Herpetic Whitlow - even if host has antibodies, infection can be induced with a sufficient viral inoculum.
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What kind of lesions occur in Varicella? What comes with it?
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cutaneous lesion, intensely pruritic vesicles.
Fever and malaise |
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How is varicella spread?
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Direct contact or air-borne droplets
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Do oral lesions occur in varicella?
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Yes, but generally they are not as symptomatic as the cutaneous lesions. Few, 1-2mm shallow oral ulcers may develop at any intra oral site
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What is the tx and prognosis?
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Tx is symptomatic, but if caught within 1 day of onset, acyclovir.
Good prognosis, 1 in 600 require hospitalization. 10-20% of population get reactivation in the form of Shingles. |
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What is the tx for Herpes ZOSTER?
What is the px? |
systemic acyclovir, 5x the dosage of HSV if early in the course of the disease
Good - resolve in 2-3 weeks Post herpetic neuralgia can develop |
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What type of virus is Coxsackie? What type of infection does it cause and in who?
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picoRNA
'enterovirus' infection Cocksackie A (1-23) or B(1-6)causes Herpangina in children aged 1-4. A16 usually, but A5, A9, A10 and others cause Hand, Foot and Mouth Disease |
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What are the symptoms of Herpangina?
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Sore throat
fever 1-2mm oral ulcers localised to posterior soft palate/tonsillar pillar region |
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What is the tx of Herpangina?
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Self-limiting process that resolves in 7-10 days.
Tx is supportive - analgesics, antipyretics, topical anaesthetics |
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What are the symptoms of Hand, Foot and Mouth Disease?
Dx? Tx? Px? |
Oral lesions (shallow ulcers 2-7mm in diameter. buccal and labial mucosa and tongue most common)
Skin lesions 1-3mm erythematous macules that may develope a central vesicle Dx on clinical manifestations Tx is supportive Px resolves in 7-10 days, good prognosis |
