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16 Cards in this Set
- Front
- Back
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DOC for thrush, non-disseminated coccidioidomycosis, and non-meningococcal cryptococcus.
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Fluconazole
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What class of drugs does Fluconazole particularly inhibit?
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Statins
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DOC, in combination with amphotericin B, for cryptococcal meningitis?
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Flucytosine
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ADR of flucytosine?
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Bone marrow suppression resulting in aplastic anemia
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DOC for onychomycosis (fungal infection of the nail)?
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Griseofulvin
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How long must Griseofulvin be used to treat a fungal infection of the nail?
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4 months
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ADR of Griseofulvin?
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photosensitvity
lupus-like symptoms or exacerbation of current lupus may decrease the effects of Warfarin or oral contraceptives because its a potent P450 inducer |
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SHANE!! The DOC for the treatment of blastomycosis, histoplasmosis, and sporotrichosis?
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Itraconazole
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Guy takes omeprazole and is prescribed Itraconazole -- will the itraconazole work better or worse?
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WORSE - itraconazole needs gastric acid in order to be properly absorbed
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The biggest ADR of itraconazole?
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HEPATOTOXIC -- has been known to cause liver failure within the first week of being used
also, potent P450 INHIBITOR -- leading to increased concentrations of other drugs |
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DOC for vaginal candidiasis?
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Miconazole
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Oral candidiasis DOC?
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Nystatin
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DOC for tinea capitis?
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Terbinafine
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ADR for Terbinafine?
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Hepatotoxic, neutropenia, may cause or exacerbate Lupus.
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Used in the treatment of deep tissue candidal infections and invasive aspergillosis? Also, the DOC for rare, aggressive fungal infections like Scedosporium apiospermum?
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Voriconazole
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What do ALL imidazoles have in common?
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Hepatotoxicity and multiple drug interactions
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