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6 Cards in this Set
- Front
- Back
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Host factors in selecting and antibiotic? |
Age Social history Family Hx Immunocompromised or competent Organs system failure co-morbid conditions (i.e. opportunistic infections) |
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What to consider when examining site of infection? |
normal flora common pathogens community or hospital acquired risk factors for infection |
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What PK characteristics of antimicrobial agent are important? |
absorption- IV vs. PO vs. IM distribution- lipophilicity, extracellular volume, extracellular vs. intracellular organisms elimination- kidney and creat clearance, liver disease, biliary tract, active metabolites |
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Empiric Treatment? |
"best guess"- based on physical exam and PMHx |
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Definitive treatment? |
adjustment of therapy after course is known.
i.e. switching from levofloxacin to trimethoprim-sulfamethoxazole after urine culture returns positive for sensitive E.Coli |
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Prophylactic treatment? |
used to prevent infection.
i.e. tell UTI patient with recurrent symptoms to take one Bactrim following sex. Also used in surgical setting to prevent surgical site infections. |
