Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
11 Cards in this Set
- Front
- Back
|
What are cytokines?
|
Cytokines are small, non-antibody, secreted proteins functioning in communicating between cells (immune cells and other cells)
|
|
|
T/F
Production of cytokines require transcription/translation processes of the cytokine genes |
True
|
|
|
What cytokine property can be produced by many cell types and act on many cell types?
|
Pleiotropic
|
|
|
What cytokine property is when different cytokines can have similar actions?
|
Redundant
|
|
|
What does IL-1 do?
|
Activates NFkB and helps activated T-cells
|
|
|
What does IL-2 do?
|
Growth factor for B & T cells and it activates NK cells & monocytes
|
|
|
What is IL-4 most important for?
|
Stimulates Ig class switch from IgG1 to IgE
|
|
|
What is IL-10 important for?
|
Suppresses the inflammatory response
|
|
|
What is TNF-alpha responsible for?
|
Acute inflammation
|
|
|
What proteins are very important between the activated IL-1 receptor and NFkB activation?
|
Traf6, MyD88, and IRAK
|
|
|
How does NFkB ellicit its response?
|
It is an activated transcription factor and needs to move into the nucleus to have its effect
|
