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11 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Obligate Aerobes
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Nocardia, Pseudomonas aeruginosa, Mycobacterium tuberculosis, Bacillus
* Mycobacterium tuberculosis has prediliction for apices of teh lung |
Nagging Pests Must Breathe
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Obligate Anaerobes
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Closteridium, bacteroides, actinomyces
Lack catalase and/or superoxide dismutase and thus are susceptible to oxidative damage. Foul-smelling, difficult to culture, produce gas in tissue |
Found in GI tract
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Why are aminoglycosides ineffective against anaerobes?
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Require O2 to enter bacterial cell
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Intracellular bugs: obligate, facultative
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Obligate - Rickettsia, chlamydia
Facultative - mycobacterium, brucella, francisella, listeria, yersinia, legionella, salmonella |
Stay inside when it's Really Cold
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Examples of encapsulated bacteria
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Streptococcus pneumoniae, haemophilus influenza, neisseria minigitidis, klebsiella pneumoniae
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How to tell if encapsulated bug is present?
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Quellung reaction - if encapsulated bug is present, capsule sweels when specific anticapsular antisera are added
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What is the virulence factor of staph aureus?
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Protein A, binds Fc-IgG, inhibits complement fixation and phagocytosis
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What is the classic triad in rickettsiae?
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Headache, fever, rash (fasculitis).
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What is the treatment of choice for most rickettsial infections?
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Tetracycline
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What are the vectors for different rickettsial diseases?
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Rocky mountain spotted fever (tick) - rickettsia ricketsii
Endemic typhus (fleas) - R. typhi Epidemic typhus (human body louse) - R. prowazekii Q fever (inhaled aerosols) - Q feveri |
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What is so unusual about Q fever?
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Q fever is different bc has no rash, no vector, has negatie Weil-Felix, causative agent survives for a long time outside and does not have rickettsia as genus name.
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