Autonomic Drugs

Front 1

4 choline esters and what is their class

Back 1

muscarinic agonsts

1. acetycholine
2. methacholine (used for resp test)
3. carbachol
4. bethanechol

Front 2

alkaloids and its class

Back 2

muscarinic agonists
muscarine and pilocarpine

these are not degrated by acetylcholine esterase

Front 3

ipratropium

Back 3

quaternary amine
muscarinic antagonist

Front 4

atropine

Back 4

tiertiary amine
muscarinic antagonist

Front 5

scopalamine

Back 5

tiertiary amine
muscarinic antagonist

Front 6

benzotropine

Back 6

tiertiary amine
muscarinic antagonist

Front 7

tiertiary amine
muscarinic antagonist that are selective for M1 in CNS

Back 7

pirenzepine
telenzepine

Front 8

3 gangllion blockers

Back 8

block nicotinic

hexamethonium
mecaylamine
trimethaphan

Front 9

tubocruarine

Back 9

competitive neuromuscular junction blocker

Front 10

reversible acetylcholine esterase inhibitors

Back 10

physostigmine and neostigmine

Front 11

irreversible acetylcholine esterase inhibitors

Back 11

organophosphates ex sarin gas

Front 12

trimethaphan

Back 12

nicotinic ganglion block

Front 13

hexamethonium

Back 13

nicotinic ganglion block

Front 14

mecamylamine

Back 14

nicotinic ganglion block

Front 15

phenylephrine

Back 15

alpha 1 selective agonist

Front 16

pseudoephedrine

Back 16

alpha 1 selective agonist

Front 17

clonidine

Back 17

alpha 2 selctive agonist
Used as an anti-hypertensive drug

Front 18

methyldopa

Back 18

alpha 2 selective agonist

Front 19

dobutamine

Back 19

beta 1 selective agonist

Front 20

dopamine

Back 20

beta 1 selective agonist

Front 21

isoproterenol

Back 21

non-selective beta agonist

Front 22

albuterol

Back 22

beta 2 selective agonist

Front 23

metaproterenol

Back 23

beta 2 selective agonist

Front 24

terbutaline

Back 24

beta 2 selective agonist

Front 25

what is used to tx heart failure

Back 25

dobutamine beta 1 selective agonist

Front 26

phenoxybenzamine

Back 26

non-selective alpha blocker

Front 27

mecamylamine

Back 27

nicotinic ganglion block

Front 28

propanolol

Back 28

non-selective beta bloker

Front 29

alpha 1 blockers

Back 29

-osin
prazosin
doxazosin
terazosin
tamsulosin

Front 30

dopamine

Back 30

beta 1 agonist at moderate dose
at higher doeses have alpha fx at really high doses alpha overshadow beta fxs

Front 31

methoxamine

Back 31

alpha agonist

Front 32

tyramine

Back 32

found in fermented foods --> relase of catecholamines

Front 33

indirect sympatholytic agents

Back 33

reserpine- destroys storage vesicles
guenethdine and guanadrel- --> inside of vesicles so is released instead of catecholamines

Front 34

phenoxybenzamine and phentolamine

Back 34

non-selectively blocks alpha. orthostatic hypotension is a problem

Front 35

labetalol

Back 35

blocks alpha and beta

Front 36

carvedilol

Back 36

blocks alpha and beta

Front 37

metoprolol

Back 37

selectively blocks beta 1 and also slightly inhibits beta 2

Front 38

how do you treat glaucoma

Back 38

1. pilocarpine cholinergic to contract ciliary muscles to open schlems canal

2. beta blockers to decrease aqueous humor production

3. sypathomimetics ex alpha 2 agoninst to decrese flow and production of aq humor

Front 39

buspirone

Back 39

anxiolytic drug acts as serotonin agonist

Front 40

amantadine

Back 40

stimulates relase of dopamine
and inhibits reuptake
with anticholinergic fxs
used to tx parkinsons

Front 41

bromocriptine

Back 41

partial dopamine agonist
used to treat parkinsons

Front 42

drug types in parkinsons tx

Back 42

anti-cholinergics
dopamine agonists
inhibitors of dopamine metabolism

Front 43

levodopa/carbidopa

Back 43

first line treatment in parkinsons
increase dopamine in brain and decreses it in the periphery

Front 44

selegeline and rasagiline

Back 44

mao inhibitors to keep dopamine around

Front 45

telocapone and enacapone

Back 45

COMT inhibitos kees dopamine around