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35 Cards in this Set
- Front
- Back
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NAME ALL THE AUTACOIDS |
Bradykinin Eicosanoids Serotinin Histamine |
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hormones produced by virtually ALL CELLS |
Autacoids |
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hormones produced by SPECIFIC CELLS |
Endocrine hormones |
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When H1 receptor is activated what effect does it produced |
Vasodilation (lowers BP) Bronchoconstriction Pain and itchiness Wakefulness Contraction of endothelial cells |
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When H2 receptor is activated what effect does it produced |
HCl release Degranularion of Histamine |
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When H3 receptor is activated what effect does it produced |
Inhibits further release of histamine |
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TRIPLE RESPONSE OF LEWIS |
Flush Flare Wheal |
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obsolete use in pulmonary challenge test but is no longer used clinically |
Histamine |
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A drug that is an H1 agonist and H3 antagonist and used in the management of endolymph associated with vertigo |
Betahistine |
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H1 antihistamine is not given to patient with ____ |
Bronchial asthma |
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What generation of antihistamine is less sedating? |
2nd gen antihistamine (piperidine) |
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Powerful central anticholinergics |
Ethanolamine Ethylenediamines |
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THE MOST SEDATING CLASS OF ANTI HISTAMINE |
Ethanolamine (1st gen anti histamine)
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Drug of choice for acute dystonic crisis (form of EPS) |
Diphenhydramine |
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Ethanolamine drugs used to manage motion sickness |
Diphenhydramine Dimenhydronate |
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What is the active form of Hydroxyzine? |
Cetirizine |
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Piperazine drugs used to manage motion sickness |
Meclizine Cyclizine |
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Stages of General Anesthesia |
ANALGESIA DELIRIUM/EXCITATION SURGICAL ANESTHESIA MEDULLARY PARALYSIS AESM |
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Used to manage serotonin syndrome (hyperthermia) |
Cyproheptadine |
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Most potent H2 antihistamine |
Famotidine |
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Less potent H2 antihistamine |
Cimetidine |
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H2 antihistamine that has a toxic effect of enzyme inhibition, and some anti-androgenic effect ( gynecomastia, low libido and infertility) |
Cimetidine |
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Precursor of serotonin |
Tryptophan enzyme: hydroxylase/decarboxylase |
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serotonergic drugs that is used as anxiolytic. It is partial agonist therefore it doesn't have euphoria effects and no potential for abuse |
Buspirone |
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Ergot derivative that is used to treat migraine headache and is vasoselective |
Ergotamine |
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Ergot derivative used to treat post partum bleeding, acute migraine headache and is uteroselective |
Ergonovine |
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A unique toxic effect of ergot derivative serotonergic AGONISTS |
RETROPERITONEAL FIBROSIS |
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Serotonergic antagonist used as a prophylaxis of migraine headache |
Methysergide |
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Used to treat and prevent chemotherapy induced vomiting |
Ondansetron Granisetron Dalonosetron |
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Eicosanoids are derived from ______? |
Arachidonic acid |
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PGE1 analog used in the treatment of NSAID-induced ulcer |
Misoprostol |
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PGI2 analog used in the management of primary pulmonaty hypertension |
Epoprostenol |
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PGE2 analog used as an abortifacient |
Dinoprostone |
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PGE1 analog used to treat erectile dysfunction |
Alprostadil |
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PGF 2alpha used in the management for glaucoma |
Latanoprost |
