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115 Cards in this Set

  • Front
  • Back
what are the BP parameters for HTN
>/= 140/90
what are the BP parameters for PRE-hypertension
systolic=120-139

diastolic=80-89
what amt of adults in the US have HTN
~ 25%
the incidence of HTN increases with what
AGE
the incidence of HTN is higher in what population
AFRICAN AMERICANS
HTN is a risk factor for what other dz processes
*CAD
*CHF
*CVA
*ESRD
*arterial aneurysm
what population has the HIGHEST incidence of HTN
black males
what are the contributing factors to ESSENTIAL hypertension
*increased SNS activity in response to stress
*overproduction of vasoconstictors or Na retaining hormones
*high Na intake
*LOW K and Ca intake
*increased renin secretion
*decreased endogenous vasodilators
*concurrent dz (DM, obesity)
what are some endogenous vasodilators
*NO

*prostaglandins
essential HTN accounts for what percent of all HTN
95%
if a pt is obese and NORMOtensive what is the result on the heart
dilatation
if a pt is lean and HYPERtensive what is the result on the heart
hypertrophy
if a pt is obese and HYPERtensive what is the result on the heart
dilatation and hypertrophy leading to CHF
what is the optimal range for BP
<120 systolic

<80 diastolic
what is the normal range for BP
<130 systolic

<85 diastolic
what is the high normal range for BP
130-139 systolic

85-89 diastolic
what is the BP for stage I HTN
140-159 systolic

or

90-99 diastolic
what is the BP for stage II HTN
160-179 systolic OR

100-109 diastolic
what is the BP for stage III HTN
>/= 180 systolic OR

>/= 110 diastolic
regarding tx goals for a normal pt what range would you want to get BP into
<140/90
regarding tx goals with co-existing dz what range would you want to get BP into
<130/80
what is the reasonable FIRST approach for tx of essential HTN in pts WITHOUT associated risk factors or evidence of end organ damage
lifestyle modification
what are lifestyle modifications that can be done in the treatment of essential HTN
*wt loss
*increased physical activity
*smoking cessation
*decrease ETOH intake
*adequate intake of Ca and K
*dietary salt restriction
what is the BIGGEST factor for decreasing BP from lifestyle modifications in essential HTN
weight loss
with treatment of essential HTN and post-MI what classes of drugs are recommended
*ACE inhibitor

*aldosterone antagonist

*beta blocker
with tx of essential HTN and heart failure what are the recommended drug classes
*ACE inhibitor
*aldosterone antagonist
*ARB
*beta blocker
diuretic
with tx of essential HTN and high risk for CAD what are the recommended drug classes
*ACE inhibitor
*beta blocker
*Ca channel blocker
*diuretic
with tx of essential HTN and DM what are the recommended drug classes
*ACE inhibitors
*ARB
*beta blockers
*Ca channel blocker
*diuretic
with tx of essential HTN and renal insufficiency what are the recommended drug classes
*ACE inhibitor

*ARB
what tx of essential HTN and previous CVA what are the recommended drug classes
*ACE inhibitor

*diuretic
what type of HTN has a KNOWN cause
secondary HTN
what percentage of HTN does secondary HTN account for
<5%
what type of HTN is often amenable to sx therapy
secondary HTN
what are the common etiologies for secondary HTN
*renovascular dz
*hyperaldosteronism
*aortic coarctation
*pheochromocytoma
*cushings syndrome
*renalparenchymal dz
*PIH
what is the MOST common cause of secondary HTN
renovascular dz
what is the BP in a hypertensive crisis
>180/120
with a hypertensive crisis higher BP are tolerated by what type of pt
pts with chronic HTN
what is HTN urgency
elevated BP WITHOUT evidence of target organ damage
what is HTN emergency
evidence of target organ damage
what is the tx goal in a hypertensive crisis
*gradual reduction of BP

-20% reduction in the 1st hr
-reduce to 160/110 range over next 2-6 hrs
regarding surgical and anesthetic risk HTN is associated with an increased risk of what
silent ishcemia and infarction
incidence of magnitude of what perioperative events is increased with pts with HTN
hypertensive and hypotensive events
there is little evidence that BP in what range increase complication rate in elective sx
<180/110 but greater than normal
what are concerns with the hypertensive pt with induction
hypertension and hypotension
what are the maintenance goals of anesthesia with a hypertensive pt
minimize wide swings in BP that are common to pts with HTN
what needs to be done with central neuraxis anesthesia and a hypertensive pt
special attention needs to be payed to fluid status d/t associated sympathetic block and decreased BP
what can be used to control HTN intra-op with HTN pt
*VA

*anti-hypertensives
what can be used to control hypotension intra-op with a HTN pt
*adjust anesthetic depth

*fluid resuscitation

*sympathomimetics
-ephedrine
-phenylephrine
what drugs that a HTN pt may be on prior to sx may not respond well to ephedrine or phenylephrine
*ACE inhibitors

*ARB
what are some of the possible etiologies for post-op HTN
*pain, agitation
*shivering
*bladder or bowel distention
*emergence excitement
*pre-existing HTN
*hypercapnia
*increased ICP
*autonomic dysreflexia
what should be anticipated in a pt who experienced an episode of intra-op HTN
post-op HTN

(appropriate orders for antihypertensives should be written)
what is the normal SYSTOLIC pulmonary artery pressure
18-25 mmHg
what is the normal DIASTOLIC pulmonary artery pressure
6-10 mmHg
what is the normal MEAN pulmonary artery pressure
12-16 mmHg
what is the definition of pulmonary arterial HTN
MEAN PA pressure > 25 ar rest OR

MEAN PA pressure > 30 with exercise
how common is primary or idiopathic pulmonary HTN
RARE

(1-2 / 1,000,000)
what is the median survival following diagnosis of primary pulmonary HTN
2.8 yrs
who is primary pulmonary HTN predominantly seen in
young women
primary HTN occurs in the ABSENCE of what
*L sided heart or valvular dz
*congenital heart dz
*myocardial dz
*resp dz
*connective tissue disorder
*thromboembolic dz
responsiveness of pulmonary HTN to vasodilators is determined how
by admin of
*prostacyclin
*NO
*adenosine
*prostaglandin E1
what is defined as "responsiveness" to a vasodilator in pulmonary HTN
a decrease in PVR and a mean PA pressure of >/= 20%
what amt of pts with primary pulmonary HTN will have a positive response to vasodilators
~25%
what are the risks of hypoxemia in pulmonary HTN
*R to L shunting thru a patent foramen ovale
*exertion resulting in increased o2 extraction in light of a relatively fixed CO
*perfusion of poorly ventilated alveoli d/t VQ mismatch
what are the various tx for pulmonary HTN
*o2 *diuretics
*anticoagulation
*Ca channel blockers
*phosphodiesterase inhibitors
*inhaled NO
*prostacyclins
*endothelin receptor anatgonist
*sx
with sedation of pt with pulmonary HTN what do you want to do
*be judicious to avoid hypoxia and hypercapnia

*supply supplemental o2
what agents are good for the induction of a pt with pulmonary HTN
thiopental and propofol
what agents for induction of a pt with pulmonary HTN may inhibit pulmonary vasodilation
*ketamine

*etomidate
what are the pros with VA in the maintanence of a pulmonary HTN pt
they are potent bronchodilators
what are the cons with VA in the maintanence of a pt with pulmonary HTN
they decrease systemic vascular resistance with R to L shunt and increase shunt
what drugs do you want to avoid in the maintanence of anesthesia with a pulmonary HTN pt
drugs which produce histamine release
what does positive pressure ventilation do with pulmonary HTN pts
improves oxygenation
ventilation settings with a pulmonary HTN pt must be appropriate to avoid what things
*hypoxia
*hypercapnia
*acidosis
*decrease in venous return
what monitors are appropriate in sx's with a pulmonary HTN pt
invasive monitors are appropriate in all but minor sx
what is the post-op care for a pulmonary HTN pt
*adequate pain control

*continued intensive monitoring
with labor and delivery and pulmonary HTN what type of anesthetic management would you choose
epidural analgesia with dilute local anesthetic and narcotic
with a c-section and pulmonary HTN what anesthetic tech would you choose
epidural is the most likely choice in the non-emergency setting

(general if emergency)
what type of anesthesia should you AVOID with a c-section and pulmonary HTN
spinal anesthesia d/t sudden decrease in SVR
what type of monitoring would you do for a c-section with pulmonary HTN
*a-line

*pulmonary arterial catheter
what is the maternal mortality with pulmonary HTN

why?
~50%

-primarily d/t CHF in labor and the early postpartum period
what is acute benign pericarditis
*viral etiology

*does NOT involve a sig effusion or tamponade

*rarely progressive
what type of presentation does pericarditis have following an MI
acute presentation OR

delayed presentation (dresselers syndrome)
acute presentation of pericarditis following an MI is seen when
1-3 days following transmural MI
delayed presentation of pericarditis following an MI is seen when
weeks to months after an MI
what is the dx criteria for acute pericarditis
*chest pain

*friction rub

*EKG changes
what is the tx for acute pericarditis
*salicylates

*NSAIDs

*corticosteroids
when does a pericardial effusion result in tamponade
when the pressure in the pericardial space interferes with cardiac filling
normally the pericardial space holds how much fluid
15-50 ml
symptoms of pericardial effusion and tamponade are related to what
compression of adjacent structures

OR

related to pericardial restraint
what are the symptoms of pericardial effusion and tamponade r/t compression of adjacent structures
*dyspnea
*cough-hoarsness
*anorexia-dysphagia
*chest pain
what are the symptoms of pericardial effusion and tamponade r/t pericardial restraint
*tachycardia
*JVD
*hepatmegaly
*peripheral edema
what is the mechanism for a cardiac tamponade
diastolic collapse d/t pressure imposed by the pericardium impairs diastolic filling of the chambers thereby reducing SV and CO
what are the compensatory mech with cardiac tamponade
*tachycardia

*peripheral vasoconstriction
what are the physical findings with cardiac tamponade
*kussmauls sign

*pulsus paradoxus

*becks triad
what is becks triad
1-quiet heart sounds

2-increased JVD

3-hypotension
how is cardiac tamponade dx
*echo**

*CT/MRI

*EKG (not a really good diagnostic tool)
what is the tx for cardiac tamponade
*removal of fluid

*temporizing measures
how is fluid removed in cardiac tamponade
*pericardiocentesis

*pericardiostomy (pericardial window)
what are temporizing measures for cardiac tamponade
*intravascular volume expansion

*increase contractility

*correction of any metabolic acidosis
what regarding anesthetic management in the presence of hemodynamically significant cardiac tamponade can result in life-threatening hypotension
general anesthesia and positive-pressure ventilation
in the anesthetic management of pts with cardiac tamponade what things do you want to maintain
*CO
*contractility
*adequate preload
*SR
in the anesthetic management of pts with cardiac tamponade what things do you want to AVOID
*decreases in systemic vascular resistance
*decreases in venous return
*bradycardia
what types of monitors should be used in the anesthetic management of pts with cardiac tamponade
*arterial line

*central venous pressure
what type of induction and maintenance drugs should be used in pts with cardiac tamponade
*ketamine (good choice)

*bzd?

*MR?
what is constrictive pericarditis
pericardium becomes a rigid shell d/t adhesions &/or scarring

(over time may become calcified)
what is diastolic filling in constricitive pericarditis
IMPAIRED like with cardiac tamponade
what is the treatment for constrictive pericarditis
stripping of the pericardium

(which may be closely adherent to the myocardium)
what may occur during the tx for constrictive pericarditis
*may involve sig blood loss

*may require cardiopulmonary bypass
what are the goals of anesthetic management of constrictive pericarditis
maintenance of:
*HR
*contractility
*SVR
*venous return
anesthetic drug selection with constrictive pericarditis will depend on what
severity of hemodynamic compromise
with severe hemodynamic constrictive pericarditis anesthetic management should be treated similar to what
cardiac tamponade
when is pericardial laceration common
in rapid deceleration injuries to the chest wall
if a pericardial laceration is associated with laceration of adjacent structures it may result in what
cardiac herniation
cardiac herniation would be managed similar to what condition
cardiac tamponade
when should you have a high suspicion for cardiac contusion
with rapid deceleration injuries
what should you be alert for in cardiac contusion
*ST-T abnormalities

*dysrhythmias