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107 Cards in this Set
- Front
- Back
DNA |
Our genes |
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How many molecules do most human cells have? |
46 |
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Bases to DNA (4) |
Adenine, Thymine, Cytosine, Guanine |
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DNA Base pairs |
A-T and C-G |
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Essential role of DNA |
Carry instructions called genes for the synthesis of proteins |
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Chromatin |
Fine, filamentous material complexed with proteins in the nucleus of a cell |
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RNA |
Single helix one nucleotide chain |
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3 forms of RNA |
MessengerRNA TransferRNA RibosomalRNA |
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Base pairs of RNA |
A-U (Uracil) C-G |
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Essential function of RNA |
To interpret the code in DNA and use those instructions to synthesize proteins |
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Gene |
Information containing segment of DNA that codes for the production of a molecule of RNA |
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46 chromosomes |
In 2 sets of 23 each, one from each parent |
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Condon |
Sequence of 3 nucleotides that together form a unit of genetic code in a DNA or RNA molecule |
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3 base sequence in mRNA |
Condon |
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Genetic code expressed in |
Condons |
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Protein synthesis |
When a gene is activated a mRNA is made- mirror image of a gene |
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Step from DNA to RNA is called |
Transcription |
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The step from mRNA to protein |
Translation |
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Translation |
MRNA carries genetic code from the nucleus to cytoplasm |
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Translation occurs in 3 steps |
Initiation Elongation Termination |
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Before a cell divides |
It must duplicate its DNA so it can give complete and identical copies of its genes to each daughter cell |
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Some cells divide rapidly such as |
Stomach and skin cells |
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Some cells divide slowly such as |
Bone and cartilage |
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Some cells don't divide at all such as |
Skeletal muscle and nerve cells |
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Cell divided into 4 main parts |
G1 S G2 Mitosis |
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G1 |
Almost all tasks happen in G1, during this time synthesizes proteins, grows, and carries out is preordained tasks for the body |
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S |
Cell makes a duplicate copy of its centrioles and all of its nuclear DNA |
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G2 |
Checks the DNA and repairs any errors that we made |
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M- mitosis |
4 phases: prophase, metaphase, anaphase, telophase |
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Heredity |
Transmission of genetic characteristics from parent to offspring |
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Chromosomes occur in? Pairs |
23. One from each parent |
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Recessive allels only expressed... |
When present on both chromosomes |
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Phenotype |
Observable trait |
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Histology |
Study of tissues and how they are arranged into orgns |
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Primary tissue classes |
Epithelial Nervous Connective Muscle |
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Ectoderm |
Gives rise to the epidermis and nervous system |
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Endoderm |
Innermost layer of embryonic tissues |
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Mesoderm |
Middle layer embryonic tissue, gives rise to muscle, bone, and blood among other tissues |
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Epithelial tissue |
Covers body surface, lines body cavities, forms the external and internal linings of the many orgns and constitutes most glands |
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Primary function of epithelial tissue |
Protection Secretion Excretion Absorption Filtration Sensation |
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Simple and pseudostratified often have |
Goblet cells associated with them and produce protective mucus coatings over mucous membrane |
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Simple cuboidal epithelium |
Single layer of square of round cells: absorb and secrete |
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Simple squamous epithelium |
Single row of thin cells: permit rapid diffusion: secrets serous fluid |
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Simple columnar epithelium |
Single row of tall cells: absorb, secrete mucus |
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Pseudostratified epithelium |
Looks multilayered all touch basement membrane. Secretes and propel mucus |
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Stratified epithelia |
2 or more cell layers thick. Most widespread epithelium in body is stratified squamous epithelium. Come in 2 ways: keratinized or nonkeratinized |
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Keratinized stratified squamous |
Epidermis |
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Nonkeratinized stratified squamous |
Resists abrasion and penetrate of the pathogens |
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Fibrous Connective tissue |
Most diverse type of Connective tissue |
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Types of fibers (3) |
-loose Connective tissue -areolar tissue -reticular tissue |
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Areolar tissue |
Found in almost every part of the body, fibers run in random directions and are mostly collagen, most abundant in body |
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Reticular tissue |
Forms framework for organs such as lymph nodes, speen and thymus |
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Dense Connective tissues (2) |
Dense regular tissue Dense irregular tissue |
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Dense regular tissue |
Closely packed collagen fibers that run parallel to each other, Found in tendons and ligaments |
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Dense irregular tissue |
Closely packed collagen fibers that run in seemingly random directions |
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Adipose tissue |
Primary energy resivoir,adipocytes are primary cell type |
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2 kinds of fat in human |
White- most widespread Brown- found in fetus and child, highly metabolic, used for heat production |
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Hyaline cartilage |
At the end of long bones attach ribs to sternum |
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Elastic cartilage EEE |
Flexible, Found in the epiglottis and ear |
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Fibrocartalege |
Forms discs, see intervertebral discs, pubic symphysis and knee menisci; resists compression and absorbs shock |
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Osseous tissue that is hard, calcified Connective tissue |
Makes up the skeleton |
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Spongy bone |
Fills the epiphyses of long bones and middle of flat bones |
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Compact bone |
Is denser tissue that forms the external surface of all bones |
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Blood primary function |
Transport of cells, nutrients, gasses and wastes |
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Nervous tissue |
Specialized for forms of communication, by means of electrical and chemical signals. |
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Muscle tissue |
Specialized tissue to contract when stimulated thus exerting a force on other tissues |
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3 types of muscle |
Skeletal- only voluntary muscle group Cardiac- involuntary Smooth aka visceral muscle-forms layers in walls of hollow organs |
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Cell junctions 3 types |
Tight junctions Desmosomes Gap junctions |
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Exocrine glands |
Have ducts, secretion usually released to body surface or into another organ such as the mouth or intestines |
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Endocrine glands |
Loose contact with body surface and have no ducts, secreting directly into blood |
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Hyperplasia |
Tissue growth (childhood) through cell multiplication |
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Hypertrophy |
Tissue growth through size (muscle) |
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Damaged tissues can be repaired in 2 ways: |
Regeneration Fibrosis |
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Regeneration |
The replacement of dead or damaged cells by the same type of cells as before and it restores normal function to the orgn |
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Fibrosis |
The replacement of damaged tissue with scar tissue, composed mainly of collagen produced by fibroblasts |
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Atrophy |
The shrinkage of a tissue through a loss in cell size or number |
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Apoptosis |
"Programmed cell death" -normal death of cells that have completed their function and best serve the body by dying and getting out of the way |
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Integumentary system |
Consists of the skin and its accessory organs, hair, nails, cutaneous glands |
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Dermatology |
The scientific study and medical treatment of the integumentary system |
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Skin functions as |
Resistance to trauma and infection Vitamin D synthesis Sensation Thermoregulation Nonverbal communication |
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Epidermis |
-Keratinized stratified squamous epithelium, -a vascular, get nutrition via diffusion from underlying Connective tissue -has sparse nerve endings for touch and pain. |
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Stem cells |
Found only in the stratum basale |
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Keratinocytes |
The great majority of epidermal cells, role in synthesizing keratin |
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Melanocytes |
Only in stratum basale, synthesize brown to black pigment melanin. Pigment shields DNA in stratum basale from UV radiation |
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Tactile (Merkel) cells |
For touch, few in number, the cell and nerve fiber are called Merkel discs |
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Dendric (langerhans) cells |
In stratum spinosum and stratum basale, immune cells that originate from bone marrow |
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Layers of epidermis (cute little grasshoppers smell bad) |
-stratum corneum.2nd layer of epidermis -stratum lucidum -stratum granulosum -stratum spinosum -stratum basale. Deepest oldest layer |
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Dermis |
Composed mainly of collagen, well supplied with blood vessels, cutaneous glands, and nerve endings |
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Dermis layers |
Papillary layer- contains dermal papilae (fingerprints) Reticular layer- deeper much thicker, dense irregular tissue, striae (stretch marks) are formed when collagen tears |
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Melanin |
The most significant factor in skin color, eumelanin, pheomelanin, skin color varies on the amount and type of melanin produced, not difference in number of melaninocytes |
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Red skin |
Hemoglobin in blood makes you a little more red. Erythema- abnormal red |
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Orange skin |
Carotene concentrating in subcutaneous fat |
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Blue skin |
Cyanosis from a lack of o2 in blood changing Hgb |
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White, pallor skin |
Decreased blood flow, albinism- genetic lack of pigment |
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Yellow skin |
Jaundice, high levels of bilirubin in the blood, liver disease |
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Bruise |
Hematoma as a mass of clotted blood showing through the skin |
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Hair |
Composed mostly of dead keratinized cells, arrector pili- smooth muscles that extend from dermal collagen fibers to the CT sheath of the hair follicle |
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Nails |
Clear, hard derivatives of the stratum corneum, hard part of nail is Nail Plate |
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Glands |
Sudoriferous glands, sweat glands 2 types |
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2 sweat glands types |
Apocrine Merocrine/eccrine |
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Sebaceous glands |
Secrete sebum (oil substance) |
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Ceruminous glands |
Secrete cerumen (earwax) |
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Mammary glands |
Secrete milk, Found in breasts; modified apocrine sweat glands |
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Skin cancer |
Most common in head, kneck, places sun sees often |
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Abcd rule for recognize skin cancer |
-Asymmetry, one side different from other -Border irregularity: contour is not uniform but wavy -Color; often a mix of brown tan red black -Diameter; greater than 6mm |
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3 types skin cancer |
-basale cell carcinoma- most common type -squamous cell carcinoma- arises from keratinocytes of the stratum spinosum -melanoma- arises from melanocytes; extremely aggressive |
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Burns |
First- only in epidermis Second- epidermis and part dermis Third-dermis and deeper tissue |