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43 Cards in this Set

  • Front
  • Back
forms of matter composed of
elements
chemical elements
Can't be split up by natural means
chemical symbols
Oxygen (o)
carbon (c)
hydrogen (h)
calcium (ca)
phosphorus (p)
inorganic compound
lack carbon, simple molecules
organic compound
Always contain carbon and hydrogen, usually oxygen
organic compounds
Don't dissolve easily in water (useful for building body structures), held together by covalent bonds, decompose easily, good source of energy, some macromolecules
organic macromolecules
nucleic acids (DNA and RNA)
proteins (regulate, building blocks)
lipids ( cell membrane & wall)
carbohydrates (energy)
monomers
basic building blocks of macromolecules, nucleotide (makes up DNA)
DNA
deoxyribonucleic acid, molecule of heredity
RNA
ribonucleic acid, many nucleotides Form a polymer, each nucleotide consists of :base ribose sugar and phosphate, plays role in translation if genetic info from DNA proteins
discovery of DNA structure
1953- Roslind Franklin (double helix)
Watson & Crick (structure and model)
DNA Structure
Each nucleotide consists of 3 parts: nitrogen base, penthouse sugar, phosphate group
polymer
DNA
4 nitrogenous bases
Adenine (A), guanine (g), cytosine (c), thyme (t)
DNA molecule
46 chromosomes (46 DNA molecules per cell), bases differ to make DNA different, 2 strands parallel, 3 nucleotides code a protein
Erin Chargoff
1949- specific base pairing, amount of A always equals amount of t, ( g =c), each helix is equal length, sugar - phosphate backbone is smooth, human DNA (30% a and t, 20% c and g)
sugar phosphate backbone
Always the same, only supports, on outside and 4 bases on the inside, uniqueness from combination of bases
Single strand of DNA
RNA
mRNA
Messenger, carries info from DNA to ribosome
rRNA
Form vital portions of structure of ribosomes
tRNA
essential carrier molecules for amino acids to be used in protein synthesis
difference in RNA bases
uracil (U) instead of thymine (t), RNA transcribed from DNA by enzyme called RNA polymerases
gene
segment of DNA that contains the info necessary to produce a protein
gene sequence
unique sequence of nucleotides in a gene
proteins
complete biological molecule, essential, in every biological process, macromolecules made of amino acids(arranged in a chain and join into peptides by peptide bonds), building blocks
amino acids
sequence of amino acids in a protein is defined by a corresponding gene, building blocks of proteins, essential to diet, of 20, 9 are essential
protein functions
enzymes that catalyze reactions and vital to metabolism, maintain cell shape(cell membrane), cell signaling, immune response, cell adhesion, DNA replication, cell cycle/ division
peptide
a short amino acid oligomer lacking a stable 3D structure
polypeptide
Can refer to any single linear chain of amino acids
folding of a chain of amino acids
occurs spontaneously, creates a protein, 3 levels: primary (polypeptide chain), secondary (starts to fold), tertiary (complete, 3D), Quarternary (multiple polypeptides)
primary structure
unique sequence of amino acids, determined by genes
secondary structure
results from hydrogen bonds at regular intervals along polypeptide backbone. shapes: coils (alpha helix) or folds (beta pleated sheets)
tertiary structure
interactions: hydrogen bonds among polar(charged) areas, ionic bonds between charged groups
Quarternary structure
multiple polypeptides, eg: collagen (3 polypeptides, coiled like rope), hemoglobin (2 copies and 2 kinds of polypeptides (4))
lipids
Don't dissolve in water, hydrophobic, large areas w/ non polar bonds, not polymers made of monomers
4 groups of lipids
phospholipids, fats, waxes, steroids
phospholipids
cell membrane (phospholipid bilayer), hydrophilic heads (polar), hydrophobic tails(non polar)
plasma membrane
also glycolipids and cholesterol, flexible, sturdy barrier, traffic of molecules (selectively permeable)
carbohydrates
fuel and building materials, composed of carbon, hydrogen and oxygen (1:2:1) (CH2O)
polysaccharides
complex carbs, polymers of many monosacchrides joined by glycosidic bonds, large macromolecules, glycogen( glucose, stored)
monosaccharides
simplest carbs, fuel an carbon sources, glucose, energy
dissaccharides
sugars, 2 monosaccharides joined w/ glycosidic linkage: maltose (2 glucose molecules), sucrose (glucose and fructose)
roles of carbs
Long term storage of chemical energy, part of backbone of DNA and RNA, role in cell-cell iteractions