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109 Cards in this Set

  • Front
  • Back
Hyperplasia
Excessive growth of normal cells
Iatrogenic
Complication of treatment (Iatro = provider, genic= to produce)
Idiopathic
unkown cause
Lesion
alteration of structure or response
Necrosis
Death of cells, tissue or organs
Neoplasia
Growth of new and abnormal tissue (Cancer)
Nosocomial
In the hospital (eg. infectioncaught there)
Syndrome
linked group of findings, signs, etc.
Upper Respitory Infection
URI, most common acute illness
Chronic sinusitis
Most common chronic disease
Heart disease
Leading cause of death in the US
Integumentary system
Epidermis, Dermis (Both comprise cutaneous membrane)
Hairs (Follicles)
Sebaceous glands
Sweat glands
Nails
Sensory receptors
Subcutaneous layer (lipids which attach to the rest of your body)
Skeletal system
Axial skeleton (Skull, vertebrae, ribs, sternum, sacrum, cartilages and ligaments)
Appendicular skeleton (Limbs and supporting cartilages and ligaments)
Bone marrow
Muscular system
Skeletal muscles (700)
Axial muscles
Appendicular muscles
Tendons
Nervous system
Central nervous system
Brain
Spinal cord
Peripheral nervous system
Endocrine system
Pineal gland
Pituitary gland
Thyroid gland
Parathyroid gland
Thymus
Adrenal glands
Kidneys
Pancreas
Gonads (Testes or Ovaries)
Cardiovascular system
Heart
Blood vessels:
Arteries
Capillaries
Veins
Blood
Lymphatic system
Lymphatic vessels
Lymph nodes
Spleen
Thymus
Respitory system
Nasal cavities
Paranasal sinuses
Pharynx
Larynx
Trachea
Bronchi
Lungs
Aveoli
Digestive system
Salivary glands
Pharynx
Esophagus
Stomach
Small intestine
Liver
Gallbladder
Pancreas
Large intestine
Urinary system
Kidneys
Ureters
Urinary bladder
Urethra
Male reproductive system
Testes
Accessory organs:
Epididymis
Ductus deferens
Seminal vesicles
Prostate gland
Urethra
Penis
Scrotum
Female reproductive system
Ovaries
Uterine tubes
Uterus
Vagina
Clitoris
Labia
Mammary glands
Inorganic compounds
Salt(electorlytes), Water, C02, O2, Acids, Bases
Organic: Carbohydrates
CHO 1:2:1, Monosaccharides (Glucose, fructose), Disaccharides (Sucrose, lactose, maltose), Polysaccharides (Glycogen)
Organic: Lipids
CHOPNS in other ratios, Triglycerides (3 fatty acids w/ glycerol) saturated, or unsaturated.
Cholesterol- steroids
Phospholipids-form cell walls
Organic: Proteins
CHONS, Peptides composed amino acids w/peptide bonds
Organic: Nucleic acid
CHONP, RNA and DNA composed of necleotides
Organic: High energy compounds
CHONP, ATP composed of a nucleotide and phosphate group.
Why is water the most important compound in the body?
Excellant solvent, high heat capacity, and participates in metabolic reactions of the body
What are Enzymes?
Proteins that accelerate chemical reactions in the body
Describe DNA
Chain of nucleotides each one containing a sugar(deoxyribose), a phosphate group and a nitrogenous base: Adenine+Thymine and Cytosine+Guanine held together by hydrogen bonds.
Describe RNA
Chain of nucleotides each one containing a sugar(Ribose), a phosphate group and a nitrogenous base: Adenine+Uracil and Cytosine+Guanine held together by hydrogen bonds.
Cell theory
1. Cells are the building blocks of all plants and animals
2. Cells are the smallest functioning units of life
3. Cells are produced by the division of preexisting cells
4. Each cell maintains homeostasis
Function of cell membrane
1. Physical isolation 2. Controls exchange of materials with cell walls surroundings 3. Sensitivity 4. Structural support
Function of membrane proteins
Receptors, Channels, Carriers, Enzymes, Anchors, Identifiers
Function of membrane carbohydrates
Cell lubricant and adhesive, receptors, recognition system
Protein synthesis
Transcription: Producing RNA from a single strand of DNA in the nucleus
Translation: assembly of protein by ribosomes using the RNA in the cytoplasm.
Mitosis
PMAT
Categories of info useful in describing disease
Symptoms, signs, lab abnormalities
Structural (organic)
Structural (Organic) presents recognizable changes,
!. Genetic and developmental diseases
2. Acquired injury and inflamation disease
3. Hyperplasias and neoplasms
functional (Inorganic)
Functional (Inorganic) presents no observable structural changes,
Six major causes of internal (endogenous) and external (exogenous) disease
Exo: Physical injury, microbiologic, chemical
Endo: Vascular, immunologic, metabolic
Disease strategies
Symptomatic: SOAP
Asymptomatic: Screenings, incidental findings, then SOAP
Protein categories
structural, contractile, transport, buffering, metabolic, enzymes, hormones, defense. 20 amino acids.
Four tissue types
Epithelial, connective, muscle, neural
Epithelial tissue
Cover exposed surfaces, line internal passageways, produce secretions
Connective tissue
Fill spaces, structural support, store energy
Muscle tissue
Contracts to produce movement
Neural tissue
Conducts electrical impulses, carries information
Types and functions of epithelial cells
Epithelia, glands (avascular)
Characteristics of epithelia
1. Bound closely together
2. Free surface exposed
3. Attached by basement membrane
4. Avascular
Functions of epithelia
1. Provide physical protection
2. Control permeability
3. Sensation
4. Produce specialized secretions (Exocrine and Endocrine)
Intercellular connections
Tight junctions (Strongest, interlocking proteins) Gap junction (channel proteins for coms) Desmosome (thin intercellular cement and protein filaments, eg skin)
Epithelia classification (layers, shapes)
Simple, stratified/ Squamous, cuboidal, columnar
Squamous locations
ventral body cavities, lining of heart and vessels, kidney tubules, cornea, exchange lining of lungs
Cuboidal locations
Glands, ducts, kydney tubules, thyroid gland
Columnar locations
Stomach and intestinal lining, gallbladder, uterine tubes, collecting ducts of kidneys
Psuedostratified ciliated columnar epithelea
Lining of nasal cavity, bronchi, trachea, parts of male repro tract
Transitional epithelea
Urinary bladder, renal pelvis, ureters
Stratified squamous epithelea
Skin surface, lining of mouth, throat, esophagus, rectum, anus and vagina
Classification of exocrine glands (Mode, Type)
(Mode) Merocrine, Apocrine, Holocrine/ (Type) Serous, Mucous, Mixed
Connective tissue components
Specialized cells (Blood, bone etc.), Protein fibers, Ground substance (GS + PF = matrix)
Connective tissue functions
1. Establish a structural framework
2. Transport fluids
3. Dissolve materials
4. Protect delicate organs
5. Support, surround, connect tissu
6. Store energy
7. Defend body
Classify connective tissue
Connective tissue proper (tendons, ligaments) Fluid connective tissue (Blood lymph) Supporting connective tissue (Bone, cartilage)
Connective cell populations
Fibroblast, macrophages, fat cells, mast cells
Connective tissue proper, tissue fibers
Collagen, Elastic(elastin), Reticular
Connective tissue proper, ground substance
Surrounds tissue fibers, clear, slows bacteria and other pathogens
Connective tissue proper: loose and dense
Loose(aeriolar, vascularity): beetween skin and muscles, digestive tract, around blood vessels, joints
Connective tissue proper: Adipose
Beneath skin esp. sides, butt, breast, around eyeballs and kidneys
Connective tissue proper: Dense
Between skeletal muscles and skeleton (tendons) between bones (ligaments), covering muscles
Fluid connective tissue types
Blood and lymph (Specialized cells in a fluid matrix usually water) Ateries, capillaries, interstitial fluid and veins
Blood contents
RBC, WBC, platelets all in a watery mixture called plasma
Lymph
Forms as interstitial fluid enters the lymphatic vessels which is monitored by the immune system and returned to the circulatory system
Supporting connective tissue types
carilage and bone
Cartilage
Avascular, firm gel matrix(lacunae) embedded with fibers and chondrocytes. Obtain nutrients via diffusion and is covered by the perichondrium (Inner layer of cells and outer layer of fibers)
Types of cartilage
Hyaline, elastic, fibrocartilage
Hyaline
Bone and joints
Elastic
Ear and nose (flexible)
Fibrocartilage
intervertabral discs, knee, pelvis(pubis symphosis)
Bone (Osseous tissue)
Matrix of collagen fibers and calcium salts, with large vascular sites. Osteocytes depend on diffusion through canaliculi for nutrient intake. Surrounded by periosteum except in joint cavities (hyaline)
How do epithelial and connective tissues combine to form four major types of membranes and the function of each?
Mucous
Serous
Cutaneous
Synovial
Mucous membranes (Mucosae)
Line cavities like the GI and respitory to communicate with the exterior
Serous membranes
Line internal cavities and are delicate, moist and permeable (Ventral cavities: peritoneal, pleural, and pericardial)
Cutaneous membrane
Skin covers body surface. Unlike other membranes, it is relatively thick, waterproof, and usually dry.
Synovial membrane
Located at joints or articulations and produce synovial fluid to lubricate jont cavities. (Hyaline)
Three types of muscle tissue and features of each type
Skeletal, cardiac and smooth muscle tissue (contract with interaction of filament proteins: myosin and actin)
Skeletal muscle tissue
Large mutinucleated cells(muscle fibers) tied together by collagen and elastic fibers situated in striations. Skeletal muscles are striated voluntary muscles because we can control contraction through the CNS.
Cardiac muscle tissue
Found only in heart and contain intercalated discs. They are striated involuntary muscles.
Smooth muscle tissue
Found in walls of blood vessels, hollow organs and in layers around various tracts (like the GI) No striations= Nonstriated involuntary muscle.
Basic structure and role of neural tissue.
Conducts electrical impulses and relays information and is composed of neurons and neuroglia (The glue).
Neuron contents
Soma, dendrites, axon which ends in synapse.
How tissue responds to maintain homeostasis
Inflamation: isolates area, produces swelling, warmth, redness and pain (can be infection, swelling due to a pathogen) Regeneration: repair process by fibroblasts which produce a network of collagen fibers (scar tissue) Cardiac and neural dont regen.
How aging affects tissue
Degrades, cancer.
Integumentary system
Skin, hair, nails, various glands
Integumentary components
Cutaneous membrane (Epidermis and dermis), Accessory structures (Hair follicles, Sebaceous and sweat glands, nerves, vessels, connective tissue.) On top of subcutaneous layer (Hypodermis).
Integumentary five functions
1. Protection
2. Temperature maintenance
3. Nutrient storage (Fat in deeper dermis and D3)
4. Sensory reception
5. Excretion and secretion
Epidermis
Stratified squamous epithelium with 4 or 5 layers (palms and soles)
Layers of epidermis
Stratum: Corneum, lucidium, granulosum, spinosum, germinitavum

Can Lucys G'ma spit germs
Stratum germinitavum
Large rapidly dividing stem cells and melanocytes
Stratum spinosum
Daughter cells still dividing
Stratum granulosum and lucidium
Produce keratin, a tough anti oxident protein
Stratum corneum
Dense in keratin, cells are dead. 2-4 weeks to arrive, shed in 2 weeks.
Basement membrane
firmly attaches with papilla ridges to germinativum and spinosum and forms border between dermis and epidermis. No blood directly to epidermis but nutrients diffused through basement cells.
Skin color of dermis
Interaction between 1. pigment composition and concentration and 2. dermal blood supply.
Pigmentation
Variable quantities of carotene and melanin (brown, brown/yellow, or black)
Melanocytes
Manufacture and store melanin and inject it into cells of the sratum germinativum and spinosum. Protect stem cells from UV rads.Concentrated around nuclear envelope.
UV rays
Stimulate production of D3 later converted to calcitrol, a hormone used for calcium and phosphorous absorbtion from the small intestine. In SG and SS.
Dermis
Superficial papillary layer, and deeper reticular layer