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109 Cards in this Set
- Front
- Back
Hyperplasia
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Excessive growth of normal cells
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Iatrogenic
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Complication of treatment (Iatro = provider, genic= to produce)
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Idiopathic
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unkown cause
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Lesion
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alteration of structure or response
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Necrosis
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Death of cells, tissue or organs
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Neoplasia
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Growth of new and abnormal tissue (Cancer)
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Nosocomial
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In the hospital (eg. infectioncaught there)
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Syndrome
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linked group of findings, signs, etc.
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Upper Respitory Infection
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URI, most common acute illness
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Chronic sinusitis
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Most common chronic disease
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Heart disease
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Leading cause of death in the US
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Integumentary system
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Epidermis, Dermis (Both comprise cutaneous membrane)
Hairs (Follicles) Sebaceous glands Sweat glands Nails Sensory receptors Subcutaneous layer (lipids which attach to the rest of your body) |
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Skeletal system
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Axial skeleton (Skull, vertebrae, ribs, sternum, sacrum, cartilages and ligaments)
Appendicular skeleton (Limbs and supporting cartilages and ligaments) Bone marrow |
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Muscular system
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Skeletal muscles (700)
Axial muscles Appendicular muscles Tendons |
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Nervous system
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Central nervous system
Brain Spinal cord Peripheral nervous system |
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Endocrine system
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Pineal gland
Pituitary gland Thyroid gland Parathyroid gland Thymus Adrenal glands Kidneys Pancreas Gonads (Testes or Ovaries) |
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Cardiovascular system
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Heart
Blood vessels: Arteries Capillaries Veins Blood |
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Lymphatic system
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Lymphatic vessels
Lymph nodes Spleen Thymus |
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Respitory system
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Nasal cavities
Paranasal sinuses Pharynx Larynx Trachea Bronchi Lungs Aveoli |
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Digestive system
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Salivary glands
Pharynx Esophagus Stomach Small intestine Liver Gallbladder Pancreas Large intestine |
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Urinary system
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Kidneys
Ureters Urinary bladder Urethra |
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Male reproductive system
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Testes
Accessory organs: Epididymis Ductus deferens Seminal vesicles Prostate gland Urethra Penis Scrotum |
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Female reproductive system
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Ovaries
Uterine tubes Uterus Vagina Clitoris Labia Mammary glands |
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Inorganic compounds
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Salt(electorlytes), Water, C02, O2, Acids, Bases
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Organic: Carbohydrates
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CHO 1:2:1, Monosaccharides (Glucose, fructose), Disaccharides (Sucrose, lactose, maltose), Polysaccharides (Glycogen)
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Organic: Lipids
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CHOPNS in other ratios, Triglycerides (3 fatty acids w/ glycerol) saturated, or unsaturated.
Cholesterol- steroids Phospholipids-form cell walls |
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Organic: Proteins
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CHONS, Peptides composed amino acids w/peptide bonds
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Organic: Nucleic acid
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CHONP, RNA and DNA composed of necleotides
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Organic: High energy compounds
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CHONP, ATP composed of a nucleotide and phosphate group.
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Why is water the most important compound in the body?
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Excellant solvent, high heat capacity, and participates in metabolic reactions of the body
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What are Enzymes?
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Proteins that accelerate chemical reactions in the body
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Describe DNA
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Chain of nucleotides each one containing a sugar(deoxyribose), a phosphate group and a nitrogenous base: Adenine+Thymine and Cytosine+Guanine held together by hydrogen bonds.
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Describe RNA
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Chain of nucleotides each one containing a sugar(Ribose), a phosphate group and a nitrogenous base: Adenine+Uracil and Cytosine+Guanine held together by hydrogen bonds.
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Cell theory
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1. Cells are the building blocks of all plants and animals
2. Cells are the smallest functioning units of life 3. Cells are produced by the division of preexisting cells 4. Each cell maintains homeostasis |
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Function of cell membrane
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1. Physical isolation 2. Controls exchange of materials with cell walls surroundings 3. Sensitivity 4. Structural support
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Function of membrane proteins
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Receptors, Channels, Carriers, Enzymes, Anchors, Identifiers
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Function of membrane carbohydrates
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Cell lubricant and adhesive, receptors, recognition system
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Protein synthesis
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Transcription: Producing RNA from a single strand of DNA in the nucleus
Translation: assembly of protein by ribosomes using the RNA in the cytoplasm. |
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Mitosis
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PMAT
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Categories of info useful in describing disease
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Symptoms, signs, lab abnormalities
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Structural (organic)
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Structural (Organic) presents recognizable changes,
!. Genetic and developmental diseases 2. Acquired injury and inflamation disease 3. Hyperplasias and neoplasms |
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functional (Inorganic)
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Functional (Inorganic) presents no observable structural changes,
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Six major causes of internal (endogenous) and external (exogenous) disease
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Exo: Physical injury, microbiologic, chemical
Endo: Vascular, immunologic, metabolic |
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Disease strategies
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Symptomatic: SOAP
Asymptomatic: Screenings, incidental findings, then SOAP |
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Protein categories
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structural, contractile, transport, buffering, metabolic, enzymes, hormones, defense. 20 amino acids.
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Four tissue types
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Epithelial, connective, muscle, neural
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Epithelial tissue
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Cover exposed surfaces, line internal passageways, produce secretions
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Connective tissue
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Fill spaces, structural support, store energy
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Muscle tissue
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Contracts to produce movement
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Neural tissue
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Conducts electrical impulses, carries information
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Types and functions of epithelial cells
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Epithelia, glands (avascular)
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Characteristics of epithelia
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1. Bound closely together
2. Free surface exposed 3. Attached by basement membrane 4. Avascular |
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Functions of epithelia
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1. Provide physical protection
2. Control permeability 3. Sensation 4. Produce specialized secretions (Exocrine and Endocrine) |
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Intercellular connections
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Tight junctions (Strongest, interlocking proteins) Gap junction (channel proteins for coms) Desmosome (thin intercellular cement and protein filaments, eg skin)
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Epithelia classification (layers, shapes)
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Simple, stratified/ Squamous, cuboidal, columnar
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Squamous locations
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ventral body cavities, lining of heart and vessels, kidney tubules, cornea, exchange lining of lungs
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Cuboidal locations
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Glands, ducts, kydney tubules, thyroid gland
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Columnar locations
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Stomach and intestinal lining, gallbladder, uterine tubes, collecting ducts of kidneys
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Psuedostratified ciliated columnar epithelea
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Lining of nasal cavity, bronchi, trachea, parts of male repro tract
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Transitional epithelea
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Urinary bladder, renal pelvis, ureters
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Stratified squamous epithelea
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Skin surface, lining of mouth, throat, esophagus, rectum, anus and vagina
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Classification of exocrine glands (Mode, Type)
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(Mode) Merocrine, Apocrine, Holocrine/ (Type) Serous, Mucous, Mixed
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Connective tissue components
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Specialized cells (Blood, bone etc.), Protein fibers, Ground substance (GS + PF = matrix)
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Connective tissue functions
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1. Establish a structural framework
2. Transport fluids 3. Dissolve materials 4. Protect delicate organs 5. Support, surround, connect tissu 6. Store energy 7. Defend body |
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Classify connective tissue
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Connective tissue proper (tendons, ligaments) Fluid connective tissue (Blood lymph) Supporting connective tissue (Bone, cartilage)
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Connective cell populations
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Fibroblast, macrophages, fat cells, mast cells
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Connective tissue proper, tissue fibers
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Collagen, Elastic(elastin), Reticular
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Connective tissue proper, ground substance
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Surrounds tissue fibers, clear, slows bacteria and other pathogens
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Connective tissue proper: loose and dense
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Loose(aeriolar, vascularity): beetween skin and muscles, digestive tract, around blood vessels, joints
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Connective tissue proper: Adipose
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Beneath skin esp. sides, butt, breast, around eyeballs and kidneys
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Connective tissue proper: Dense
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Between skeletal muscles and skeleton (tendons) between bones (ligaments), covering muscles
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Fluid connective tissue types
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Blood and lymph (Specialized cells in a fluid matrix usually water) Ateries, capillaries, interstitial fluid and veins
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Blood contents
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RBC, WBC, platelets all in a watery mixture called plasma
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Lymph
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Forms as interstitial fluid enters the lymphatic vessels which is monitored by the immune system and returned to the circulatory system
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Supporting connective tissue types
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carilage and bone
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Cartilage
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Avascular, firm gel matrix(lacunae) embedded with fibers and chondrocytes. Obtain nutrients via diffusion and is covered by the perichondrium (Inner layer of cells and outer layer of fibers)
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Types of cartilage
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Hyaline, elastic, fibrocartilage
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Hyaline
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Bone and joints
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Elastic
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Ear and nose (flexible)
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Fibrocartilage
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intervertabral discs, knee, pelvis(pubis symphosis)
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Bone (Osseous tissue)
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Matrix of collagen fibers and calcium salts, with large vascular sites. Osteocytes depend on diffusion through canaliculi for nutrient intake. Surrounded by periosteum except in joint cavities (hyaline)
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How do epithelial and connective tissues combine to form four major types of membranes and the function of each?
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Mucous
Serous Cutaneous Synovial |
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Mucous membranes (Mucosae)
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Line cavities like the GI and respitory to communicate with the exterior
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Serous membranes
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Line internal cavities and are delicate, moist and permeable (Ventral cavities: peritoneal, pleural, and pericardial)
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Cutaneous membrane
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Skin covers body surface. Unlike other membranes, it is relatively thick, waterproof, and usually dry.
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Synovial membrane
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Located at joints or articulations and produce synovial fluid to lubricate jont cavities. (Hyaline)
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Three types of muscle tissue and features of each type
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Skeletal, cardiac and smooth muscle tissue (contract with interaction of filament proteins: myosin and actin)
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Skeletal muscle tissue
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Large mutinucleated cells(muscle fibers) tied together by collagen and elastic fibers situated in striations. Skeletal muscles are striated voluntary muscles because we can control contraction through the CNS.
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Cardiac muscle tissue
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Found only in heart and contain intercalated discs. They are striated involuntary muscles.
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Smooth muscle tissue
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Found in walls of blood vessels, hollow organs and in layers around various tracts (like the GI) No striations= Nonstriated involuntary muscle.
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Basic structure and role of neural tissue.
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Conducts electrical impulses and relays information and is composed of neurons and neuroglia (The glue).
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Neuron contents
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Soma, dendrites, axon which ends in synapse.
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How tissue responds to maintain homeostasis
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Inflamation: isolates area, produces swelling, warmth, redness and pain (can be infection, swelling due to a pathogen) Regeneration: repair process by fibroblasts which produce a network of collagen fibers (scar tissue) Cardiac and neural dont regen.
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How aging affects tissue
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Degrades, cancer.
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Integumentary system
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Skin, hair, nails, various glands
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Integumentary components
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Cutaneous membrane (Epidermis and dermis), Accessory structures (Hair follicles, Sebaceous and sweat glands, nerves, vessels, connective tissue.) On top of subcutaneous layer (Hypodermis).
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Integumentary five functions
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1. Protection
2. Temperature maintenance 3. Nutrient storage (Fat in deeper dermis and D3) 4. Sensory reception 5. Excretion and secretion |
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Epidermis
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Stratified squamous epithelium with 4 or 5 layers (palms and soles)
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Layers of epidermis
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Stratum: Corneum, lucidium, granulosum, spinosum, germinitavum
Can Lucys G'ma spit germs |
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Stratum germinitavum
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Large rapidly dividing stem cells and melanocytes
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Stratum spinosum
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Daughter cells still dividing
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Stratum granulosum and lucidium
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Produce keratin, a tough anti oxident protein
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Stratum corneum
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Dense in keratin, cells are dead. 2-4 weeks to arrive, shed in 2 weeks.
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Basement membrane
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firmly attaches with papilla ridges to germinativum and spinosum and forms border between dermis and epidermis. No blood directly to epidermis but nutrients diffused through basement cells.
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Skin color of dermis
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Interaction between 1. pigment composition and concentration and 2. dermal blood supply.
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Pigmentation
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Variable quantities of carotene and melanin (brown, brown/yellow, or black)
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Melanocytes
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Manufacture and store melanin and inject it into cells of the sratum germinativum and spinosum. Protect stem cells from UV rads.Concentrated around nuclear envelope.
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UV rays
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Stimulate production of D3 later converted to calcitrol, a hormone used for calcium and phosphorous absorbtion from the small intestine. In SG and SS.
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Dermis
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Superficial papillary layer, and deeper reticular layer
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