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6 Cards in this Set
- Front
- Back
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Traditional Antipsychotics (Phenothiazines): |
•Chlorpromazine (Thorazine) •Thioridazine (Mellaril) –Decrease DA activity: Block D2 Receptors –Blocks NE -> orthostatic hypotension –Decrease sex drive –Increase prolactin –Mess up body temp regulation –Not addictive |
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2nd Generation Antipsychotics |
Clozapine (Clozaril) Risperidone (Risperdal) |
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Clozapine (Clozaril) |
–Decreases DA, 5-HT activity: Blocks D4, 5-HT2a –Relieves pos (DA) & neg (5-HT2a) symptoms –Agranulocytosis |
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Risperidone (Risperdal) |
–Decreases DA activity: Blocks D2 –Relieves pos & neg Symptoms –Less effective, More safe |
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3rd Generation Antipsychotic |
Aripiprazole (Abilify) |
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Aripiprazole (Abilify) |
–Regulates DA activity: Not D2 antagonist –DA partial agonist –Modulator –If high DA -> less agonist (Does not increase activity) –If low DA -> more agonist (increases activity) |
