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18 Cards in this Set
- Front
- Back
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What are the typical antipsychotics
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CHlorpromazine,
Thioridazine Fluphenazine Haloperidol |
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What receptors do the typical antipsychotics work on
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ALL block D2...But Typicals especially D2..
Chlorpromazine alpha 1=D2 Haloperidon D2>D1 |
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What are the atypical antipsychotics
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Clozapine
Olazapine Risperidone Aripriprazole |
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WHat receptors do the Atypical antipsychotics work on?
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5HT2 and D4 receptors they help allievate the NEGATIVE symptoms of psychoses
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What Typical causes Nueroleptic Malignant Syndrome
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Haloperidol
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Which Typical gives u <3 Tox. MAy cause Torsades
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Thoridazine
Zisperidone DOES TOO (ATYPICAl) |
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What is a major side effect of Clozapine?
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Agranulocytosis and wirght gain
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What Atypical is a partial agonist of D2 receptor and blocks the 5HT2 receptor
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Aripriprazole
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What role does the MESOLIMBIC PATHWay play.
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Dopamine travels from the MIDbrain tegmental---> Nucleus Accumbens..this may cause delusions, Hallucinations and + symptoms of schizo
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What role does the mesocortical pathway play?
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Goes from Midbrain 2 PREfromntal lobe cortex causes Apathy, wothdrawl, lack of motivation
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What role does the nigrostriatal pathway play?
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Goes from the substancia nigra to the striatum... INHBITION of the NIGROSTRIATAL pathway--> Extrapyramidal SYmptoms
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What role does the tubuloinfundibular pathway play?
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It goes from the hypothalmus to the pituitary..Inhbits the release of Prolactin
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What is Tardative dyskinesia
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It is ORO-Facial Dyskinesia With widespread choreoathectosis or dystonia
Caused by Up Reg Striatal D2..months - years of Tx. |
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What is Acute Dystonia
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Spasm of tongue., face, neck muscles 1-5 days use Anti-musc.agents
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What is Nueroleptic Malignant Syndrome
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Catatonia, Stupor, Unstbale BP, Myoglobinemia
TX: Dantrolene |
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What is Akathisia
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It is Motor restlessness
5-50 days Duhyraphrenamine, benzo's or propanolol may help |
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What can be used for nausea or vomiting
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Prochlorperazine- compazine
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What is used for tourette's
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Haloperidol or pimozide
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