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10 Cards in this Set
- Front
- Back
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Sulfa drugs |
Came from dyes, Domagk. Folic acid, non toxic, broad, static, anti metabolism |
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Quinolones |
Synthetic, DNA gyrase, end in oxacin, broad, cidal, non toxic |
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Penicillin |
Natural and semi synthetic, duchesne, Fleming. Beta lactam ring. Targets cell wall synthesis. Narrow to broad. Cidal. Low toxicity |
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Cephalosporins |
Similar to penicillin, have beta lactam ring and target cell wall synthesis. |
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Tetracyclines |
Natural and semi synthetic. Protein synthesis. Small Ribosomal subunit and block tRNA binding to A site. Static, broad. Can be toxic if the dose is high. |
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Aminoglycosides |
Natural, semi synthetic. Protein synthesis, binds to small ribosomal subunit, blocking initiation. Narrow (g neg). Cidal |
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Macrolides |
Natural, semi synthetic. Protein synthesis, binds to large ribosomal subunit, blocking elongation. Narrow (g pos) static |
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Vancomycin |
Natural, cell wall. Narrow (g pos). Cidal |
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Chloramphenicol |
Nat and synthetic. Small, protein synthesis. Large ribosomal subunit, elongation. Static, broad |
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Ehrlich |
Magic bullet. Cured syphilis with salvarsan |
