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3 Cards in this Set
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Polyene antibiotics |
Binds to ergosterol in cell membrane. And increases membrane permeability. Leakage of intracellular content. Death of fingi. |
Amp B, Nyacin, Hamycin |
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Heterocyclic antibiotics |
Interact with polymerized microtubules. Disrupts mitotic spindles. Spindle poison inhibits fungal mitosis |
Griseoflavin |
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Azoles inhibit ergosterol synthesis inhibiting 14@ demethylase enzyme. |
Dermatophytic infections. Candida infections |
Imidazoles:- Ketakonazole, micanozole, clotrimazole Triazoles. :- Flucanazole, Itraconazole, Voriconazole |
