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17 Cards in this Set
- Front
- Back
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MOA scopolamine in motion sickness
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blocks M receptors in neuronal pathway from vestibular apparatus
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Prochlorperazine - MOA as antiemetic
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Block D2 receptors in CTZ and NTS
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Ondansetron - MOA as antiemetic
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Block 5HT3 receptors in CTZ, NTS and gut
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low dose metoclopramide - MOA as antiemetic
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Block D2 receptors in CTZ and NTS
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high dose metoclopramide - MOA as antiemetic
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Block D2 and 5HT3 receptors in CTZ, NTS and gut
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aprepitant - MOA as antiemetic
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Block NK1 receptors in CTZ and NTS
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prochlorperazine - efficacy in which of the following?
motion sickness PONV CINV (low emetogenic potential) CINV (high emetogenic potential) |
PONV
CINV (low emetogenic potential) |
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ondansetron - efficacy in which of the following?
motion sickness PONV CINV (low emetogenic potential) CINV (high emetogenic potential) |
PONV
CINV (low emetogenic potential) CINV (high emetogenic potential) |
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high dose metoclopramide - efficacy in which of the following?
motion sickness PONV CINV (low emetogenic potential) CINV (high emetogenic potential) |
CINV (low emetogenic potential)
CINV (high emetogenic potential) |
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aprepitant - efficacy in which of the following?
motion sickness PONV CINV (low emetogenic potential) CINV (high emetogenic potential) |
PONV
CINV (low emetogenic potential) CINV (high emetogenic |
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would dexamethasone be used alone to treat CINV (highly emetogenic potential)?
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No, added to 5HT3 blocker and aprepitant
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Side effects of metoclopramide
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CNS problems, extrapyramidal reactions (movement disorders)
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which drug causes extrapyramidal reactions?
ondansetron metoclopramide aprepitant scopolamine dimenhydrinate |
metoclopramide
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Which would you used for diabetic gastroparesis?
prochlorperazine ondansetron metoclopramide scopolamine aprepitant |
metoclopramide
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MOA metoclopramide in increasing gut motility
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Antagonize D2 receptors
Activate 5-HT4 receptors |
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do you use a low dose or high dose of metoclopramide to increaese gut motility
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low dose
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MOA dimenhydrinate in motion sickness
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blocks M and H1 receptors in neuronal pathway from vestibular apparatus
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