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28 Cards in this Set
- Front
- Back
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two ways to vomit
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direct- thoughts sensory
indirect- chemorecpetor zone activated CTZ |
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two ways of activating the CTZ
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vagal from stomach and small intestineand emetogenic compunds
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most important application in using antiemetic
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chemotherapy induced vomiting
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which type of receptors are involved in vomiting
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serotoninm dopamine, ACH, histamine
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most effective antiemetic drug class and prototype
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serotonin receptor antagonists or ondansetron (zofran)
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highly nauseous anticancer drug
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cisplatin
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how is ondansteron more effective?
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using with dexomethasone
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why does zofran not cause extrapyramidal effects
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does not block dopamine receptors
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adverse effects of zofran
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headache, diarrhea dizziness
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another serotonin receptor antagonist
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Kytil or grani-setron
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drug that treats N+V off labelly
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dexamthosone and methylpredisone (solu-medrol)
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steroid treatment for NV -adverse effects
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not many bc it is used short term
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dopamine antagonists prototype
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phenergan or phenothiazine
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dopamine antagonists side effects
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extrrapyramidal rxns, anticholergic, hypotension, and sedation
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another dopamine antag.
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Reglan or metoclopamide
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Reglan 2 purposes and drug type
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antiemetic and prokinetic
and dopamine antagonists |
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Other name of marinol
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dronabinol and nabilone (synthetic)
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combination of THC and cannabinoid
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Sativex- in canada only
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common benzodiazepam used in NV
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lorazepam or ativan
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benefits of ativan in CINV
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control extra-pyramidal, sedation, anxiety or anticipatory NV, and production of antegrade amnesia
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Dronabinal is classified as what
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schedule III
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what is the preferred route for NV with CINV?
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orally
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SxS for motion sickness
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NV, pallor, cold sweats
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motion sickness effective when?
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prophylactically
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two types of drugs for motion sickness
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scopolamine and antihisamine
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scopolamine is what type of drug and side effects
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muscarinic agagonist- blurred vision, dry mouth, and drowiness
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most common antihistimine to help with motion sickness
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dramamine- dimenhydrinate
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side effects from dramamine
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anticholinergic affects- sedation, dry mouth, blurred vision, , urinary retention and constipation
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