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7 Cards in this Set

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Aminoglycosides MOA
inhibit bacterial protein synthesis by binding to 30S ribosomal subunit
Aminoglycosides are used primarily in infections caused by:
gram-negative enterobacteria and in suspected sepsis
Streptomycin spectrum of activity
-organisms that cause plague and tularemia
-gram(+)streptococci (combo w/penicillin)
-mycobacterium tuberculosis (combo)
Amikacin, kanamycin, gentamicin, tobramycin, neomycin, netilmicin spectrum of activity
GRAM NEGATIVE BACTERIA
-proteus
-serratia
-pseudomonas
Broadest spectrum aminoglycoside
Amikacin
AEROBIC GRAM NEGATIVE BACILLI AND ANAEROBIC GRAM NEGATIVE BACTERIAL STRAINS THAT RESIST GENTAMICIN AND TOBRAMYCIN
Aminoglycoside that may be active against gentamicin-resistant organisms
Netilmicin
Neomycin spectrum of activity
-e.coli
-klebsiella
-gram(+) (s.aureus, m.tuberculosis)