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7 Cards in this Set
- Front
- Back
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Aminoglycosides MOA
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inhibit bacterial protein synthesis by binding to 30S ribosomal subunit
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Aminoglycosides are used primarily in infections caused by:
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gram-negative enterobacteria and in suspected sepsis
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Streptomycin spectrum of activity
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-organisms that cause plague and tularemia
-gram(+)streptococci (combo w/penicillin) -mycobacterium tuberculosis (combo) |
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Amikacin, kanamycin, gentamicin, tobramycin, neomycin, netilmicin spectrum of activity
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GRAM NEGATIVE BACTERIA
-proteus -serratia -pseudomonas |
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Broadest spectrum aminoglycoside
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Amikacin
AEROBIC GRAM NEGATIVE BACILLI AND ANAEROBIC GRAM NEGATIVE BACTERIAL STRAINS THAT RESIST GENTAMICIN AND TOBRAMYCIN |
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Aminoglycoside that may be active against gentamicin-resistant organisms
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Netilmicin
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Neomycin spectrum of activity
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-e.coli
-klebsiella -gram(+) (s.aureus, m.tuberculosis) |
