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63 Cards in this Set

  • Front
  • Back
Human Energetics
Food energy: interaction between humans and environment, seeking out food sources

energy is limited in some environments, seasonality
Bioenergetics
study of the use of transfer of energy (intake, output, changes in body fat stores)

central componenet of ecology

how individuals and popularions extract energy from the environment and allocate it to various somatic functions (consequences for health , survival, fertility and life history strategy)
Energy Budget
-Maintenance for survival: homeostasis, BMR/RMR, thermoreg, thermic effect of food, physical activity, immune response

-Production: growth and development, reproduction and consequences for reproductive success (fitness)
Total Energy Expenditure (TEE)
energy requirements of person over the course of an entire day, maintenance costs and productive costs

maintenance + production
Mammalian Reproduction
constraints on female reproductive success in mammals
-energy: finite energy allocated to maintenance, growth and reproduction
-time: finite reproductive lifespan

reproductive success (fitness) requires survival, mating and rearing offspring

partial reproduction worse than non -lost time and energy tho

male reproductive success is much less constrained
Maximizing Reproductive Success
Males emphasizing mating: increase access to mates because no cost of gestation to worry about, maximizing amount of offspring

females emphasize rearing offspring, once fertilized females will not increase reproductive success by repeated mating
Male Strategies
Single male groups (ex. Gorillas) become dominant male, recruit new group, infanticide

Multi-male(chimps, humans): monitor estrus cycles, friendships and courtships, peripheral mating
Female Cost of Reproduction
milk production, long term energy costs

limited food access

increased risk of predation
Female Strategies
age of first reproduction-> youngish
age at weaning of offspring -> youngish

interbirth interval

Alloparenting (allomothering): recruiting other parents to help
Rose Frisch
Critical Fat Hypoth fo rtimign of adolescent maturation looked at ahtletes and anorexics

energy status, energy available at a certain time

reproductive function far more complicated, maturity in females more closely associated with skeletal maturation

-> the complexity of fertility

Problem: only focused on menstruation patterns/past-> ITS A SPECTRUM
Energy Dynamics and Fertility
not just about energy storage or energy status, it isnt about just one point in time, more like storage and saved up

-> issue of whether gaining or losing weight at the time (ENERGY BALANCE): psotive vs negative along with speed of weight gain or loss

also about energy flux or turnover: too high or too low
Fecundity
ability to reproduce, capability for producing offspring

not pathological but instead a functional modulation based on environment (function based on living conditions reflecting ability to have baby)
Non-Western Populations
nutritional intake and activity typically structured by necessity rather than by choice

lese horticulturalists of ituri foret, congo showing importance of energy status balance and flux in ovarian function

low overall energy intake

cycles of conception probabilities seasonally-> Harvest season has higher probability aug-dec, vs hunger season jan-july
Tamang Agropastoralists of Nepal
constant food supply but variation in energy expenditure as important variable

heavy workloads during monsoon season - neg energy balance
Jasienska et al PNAS 2006
role of fetal environment in structuring how female physiology responds to changes in energy availability

polish women 24-36 with info on birth size

High physical activity led to aovarian suppression in all groups but women born as skinny babies showed ovarian suppression with moderate physical activity
Role of Childhood
(Bentley), migration study of bangladeshi women in london compared to women raised in bengladesh

looked at: progesterone levels: London>Migrant bangladeshis>Bangladeshis (women in london are more fertile), pre-purberty as a time sensitive factor to environmental conditions

Trade Off: women who live in bangladesh had greater parasitic worm presence,
Lactational Energetics
more energetically costly on a daily basis among humans and non human primates

breast milk prod places huge energy demands on women's bodies (mult. ways to offset those demands that involve more than just eating more or doing less- social support)
Lactation Amenorrhea
Ovarian function resumes when frequency and duration of nursing decreases -> adaptive to avoid having too many close spaced pregnancies
Maternal Depletion Syndrome
in marginally nourished populations repeated and closely spaced reproductive cycles can affect maternal energy reserves (ie fat lean muscle)

can lead to mds and nutritional stress, compromises maternal well being and offspring health

similar trend not observed for skeletal calcium stores (doesnt effect the skeletal system between the mom or baby)
Role of Biosocial Context
women are flexible in strategies they use to deal with reproductive costs
Physiological
increased energy intake (EI): mobilize fat stores; decreased energy expenditure (EE) [reduce BMR, decrease physical activity level PAL]

also cultural norms and traditions, social support
Mate Preferences and Reproductive Potential
males prefer certain physical traits in femals, especially narrow waists and large breasts along with low whr some groups high levels of body fat
Male Reproductive Energetics
little metabolic effort towards offspring

low cost of gamete production (sperm is cheap)
often expend considerable energy on mating effort, males can increase fitness by maximizing mate access, behavior and physiology such as production and maintenance of muscle mass
Growth Adaptation in GHRH
(pygmys)
<5ft tall
Grwoth hormone releasing hormone (GHRH) fromt he hypothalamus triggers growth hormone (Somatotrophin) synthesis and release by anterior pituitary

regulation of cell division in muscle and general growth promoting effect throughout the body

acts directly on target tissues and additionally works through insulin line growth factor - IGF1, secreted by liver and target tissues
-> Production stunted by undernurtition

Growth occurs by saltation (stasis & growth)

Pygmys decreased IGF-1 and decrease in receptors
Macronutrients
protein, fat, carbohydrates
Micronutrients
vitamins and minerals
Energy (Calories)
carbs & protein: 4kcal per gram
Fat: 9kcal per gram (cannot pass inutero, passed well through breast milk tho)
Bioavailability
The fraction of nutrients consumed that are absorbed influenced by the combination of foods eaten

Iron absorbtion INHIBITED by phytates (corn & veggies)

Iron promoted by other foods (rich in viatmin C)
RDA Recommended Dietary Allowance
nutrients set so that nearly everyone gets enough, more is not always better (overconsumption of some nutrients), overnutrition is hard to study because of reporting bias, evaluation: food frequency, twenty four hour recall, food diary, and something
Food Frequency Questionnaire
survey individuals on the type, quantity and frequency of specific food consumption

Limits: data not the most idea, limited by subject memory, food difficult to quantify by subject
Food Weighing
One of the more ideal food assessment methods as it provides the best data

most invasive method since you must weigh everything that has been eaten and that has not been eaten

because it is
Larder Survey
researcher goes into participants house and records all the food available

accompaies participant to the market to shop for food and records all purchase items

returns a week later to record what has been consumed and may even look through trash to see what was discarded
Malnutrition
Bad Nutrition, NOT undernutrition or overnutrition

deficiencies in nutrients -> poor growth as a result (ex. zinc, vit a, etc.)

PEM: Protein Energy Malnutrition, most common/important nutritional deficiency: Half of the world's children suffer undernutrition, most with PEM, adequate protein intake must include all 8 essential amino acids
Synergistic Action
Undernutrition increases risk for infectious disease
Zinc
important in the synthesis of muscle and bone and for various cellular processes

deficiency can lead to growth retardation, sexual immaturity, immunosuppression and cognitive problems, diets largely of wheat bread with high fiver and phytate can lead to malabsorption of zinc
Niacin (Vitamin B3)
involved in energy metabolism and cellular repair, can lead to Pellagra: rash skin lesions diarrhea and mental disturbance

comes from diets largely based on corn
Vitamin A
necessary for the production of rhodopsin, the eye pigment repsonsible for sensing low light situation, leads to night blindness
Rickets
Vitamin D deficiency during growth, critical for calcium absorption and metabolism and immune function

skeletal changes (poor bone strength)

Vitamin D sources: Fish skins, fortified Milk, synthesis from SUNLIGHT exposure

-> Light skin, advantageous (absorbs more sunlight in low sunlight environments)
Evenki children
1991, 1992 vs 1995:
skin fold thickness, height, weight, compared scores to US NCHS growth norms

children in 1995 significantly shorter, lighter and leaner, more stunting and wasting in 1995, levels of growth retardation similar to in developing nations, more pronounced in girls, increased certain nutritional deficiencies (rickets, etc.)

children reported with more friends had lower health
Fetal Programming (DAVID BARKER)
effects of low energy fetal environment, measured using birth weight or ponderal index as an indicator, not just low birth weight babies: continuous relationship

developmental adaptation permanently change structure, physiology and metabolism (NUTRIENT DEMAND > MATERNOPLACENTAL SUPPLY)

later shift in environmental conditions (scarcity -> abundance) predisposed to metabolic, cardiovascular and endocrine disease in adulthood

increased all cause mortality, type 2 diabetes

linked to female weight.... see slides
Gastroenteritis
inflammation of the digestive tract lining (stomach and intestines) caused by infection agent main symptoms diarreah and fever, major problem dehydration
Pollutants
defined as unwanted materials (ex lead, mercury, etc.) or energy (ex noise, or radiation) typically produced or concentrated by human activity

cigarette smoking affects fetal growth and is a major determinants of birth weight in developed countries

lead also
Psychosocial Stress
conception rate and increased risk of stress-related miscarriage (espeically in first 3 weeks of gestation)

CHRONIC Stress is an issue today

-> Disruption of postnatal growth: Failure to Thrive (psychosocial short stature), parental neglect and deprivation physical or sexual abuse, depression of digestive enzymes causing malnutrition even when adequate nutrient intake
-> Orphanage Studies
Poor growth and delayed physical and mental development

even proper hygiene, food and nutrition the abandoned infants would die, this is because overwhelmed nurses neglected to HOLD them-> negative emotional stress reducing immune function -> Death
Harlow Studies
monkeys chose comfort over food, social contact for proper learning and well-being
High Altitude Hypoxia
percent oxygen constant (~21%) but air less compressed -> fewer gas molecules

reduced oxygen availability affects all organ systems
Acute Mountain Sickness

cultrual and behavioral factors provide minimal buffereing against hypoxia
Acute Mountain Sickness
an illness that can affect mountain climbers, hikers, skiers, or travelers at high altitude (typically above 8,000 feet or 2,400 meters). Symptoms range from mild to life-threatening
Western Infant Care
push baby away (Ferberize), warn mothers about what their bodies can do TO their infants rather than FOR their babies to protect and nurture them

1970s solitary sleeping infants placed on their stomachs to promote deeper sleep, WRONG
Test Question
What is Barker's Fetal Programming Hypothesis? What are the particular adult health conditions that have been explained by fetal programming?
Age of Degenerative Disease
Rapid decrease in mortality especially childhood from infectious diseases

later massive decline in fertility
increased chronic non infectious diseases

EFFECTS: Increase in life expectancy (60s-70s), older population, population growth slows to low level
Health Change with Economic Development
Epidemiological transition to reduced infectious disease burden and increased chronic degenerative diseases:
Cardiovascular Disease
Obesity
Type II Diabetes
Hypertension
Cancers
Also decreased physical fitness and physiological work capacity

+Many diseases associated with aging

Economic Development=decrease in physical labor
Factors In Health Change
Not just because people are living longer.

Dietary Shift or "THe Nutritional Transition":
-increased saturated fats and refined sugars
-reduced traditional foods

Reduced Physical Activity:
-Technology (Cars, Remotes, etc.)
-TV viewing

Increasing BAD habits:
-Smoking, more often & at younger ages
-Alcohol consumption
-chronic psychosocial stress
Obesity
at one level its a straight forward problem: eat too much, get fat
-> It depends on each person, differences in ability to process food
Globesity
A global epidemic, double burden in developing nations: Undernutrition with over eating (Eating a lot of the wrong thing)
-> Overnutrition in other regions
Children and Obesity
Major overweight and obesity in US children:
- increased prevalence of obesity over the past several decades: BMI>95th percentile
-> Globally following the stats of the US
Health Consequences of Obesity
You dont die from being overweight but from the complications from it:
-hypertension, dyslipidemia, cardiovascular disease, sleep apnea, type 2 diabetes, osteoarthritis, respiratory problems, female reproductive issues, social stigmatization & discrimination, Endometrial, Breast & Colon cancers

-> Central Fat (abdominal area) is really problematic, fat as an endocrine organ is linked with inflammation: suffocate and prevents proper function of organs
Fat as an organ
-Endocrine Gland
-releases chemical: Leptin, fat gain/loss loops!!
Single Biggest Factor: Increased Energy Intake
especially fats and sugars and in liquid calories

frequent snacking
larger potion size
more meals outside of the home
Western Diet
calorically dense, refined calories, major contributions from refined carbs, fats especially saturated, low in protein, high salt content, many additives, low fiber content
Fast Food
Addictive, glycemic index in the body
Humans Evolved to Eat
Look at forager/hunter-gatherer populations: variation accross populations based on ecology

Paleolithic Diet- virtually no obesity
Bergmann’s Rule
Body size within a species larger
at lower temperature

-Higher body mass: Relatively lower surface area and greater
heat retention
-In warm climates, smaller body size leads to relatively higher
surface area and greater heat dissipation
Allen’s Rule
Appendages (arms & legs; also ears) within a species shorter at lower temperature

-Shorter appendages: Relatively lower surface area and greater heat retention
- In warm climates, longer appendages with relatively higher surface area leads to greater heat dissipation