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3 Cards in this Set
- Front
- Back
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Causes of sideroblastic anemia |
1. Genetic 2. Acquired: ⬇️ Vit.B6 (pyridoxal phosphate) • Isoniazid • chloramphenicol • Melphalan • Zinc overuse • Lead poisoning • Alcoholics Ttt: Removal of the toxic agent and administration of Vit.B6 |
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Drugs that inhibit megaloblastic anemia |
• PPI • H2 receptor antagonists • Metformin Therefore, in this case, VIT.B12 is taken via IM route. |
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Treatment of sickle cell anemia |
💊 Hydroxyurea ⚙️ ⬆️ fetal Hb (F) which prevents sickling and adhesion. ⬇️ requires careful monitoring to avoid leukopenia and thrombocytopenia.
💊 Crizanlizunamb ⚙️ P-selectin inhibitor
💊 Voxelotor: ⚙️ HbS polymerization inhibitor |
